Kratom, Mitragyna speciosa
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Kratom, or Mitragyna Speciosa, is a tree found in some parts of southeastern South-East Asia. It has a long history of use in this region for it's stimulant and narcotic effects. Kratom seems to be popular among older males in Thailand & Malaysia, where it is often chewed to help aid with physical labor. The working class seems to use Kratom for much the same reasons Americans use coffee. It has become somewhat of a crutch for those engaging in hard physical labor. Kratom has been made illegal, but Kratom use is still widespread, since Kratom trees grow in these regions.
Though Kratom use is popular in some parts of South-East Asia, there are still a lot of things not known about Kratom. Research has been done, but there is not a great deal of continued research. Most online information tends to originate from a limited pool of research and text. Some of the research is inconclusive and would require further studies to confirm any results. In particular, there is no clear answer as to the side effects of continued use of Kratom.

Alkaloids
There are about 25 alkaloids that have been identified in this species of tree, including mitragynine and 7-hydroxymitragynine. Mitragynine is believed to be the alkaloid responsible for most of the plants narcotic effect, but it is still unknown as to how the other alkaloids affect humans. 7-hydrohydroxymitragynine is of particular interest because it has been shown to have opiod agonistic properties, as well as profound analgesic effects. Studies involving rats have suggested that 7-hydrohydroxymitragynine is significantly more effective with regards to analgesic effects than morphine. 7-hydrohydroxymitragynine also appears to be absorbed orally better than morphine. It is likely that 7-hydrohydroxymitragynine plays a significant role in the effects of the Kratom plant when consumed. Kratom also contains the alkaloids paynanthine, speciogynine and several less abundant alkaloids.
Effects
Kratom affects the mind and body much like opiates. Physical effects include constriction of pupils, constipation, elevated blood pressure, increased heart rate, analgesia, nausea and, in high doses, a hangover can occur. Mental effects include euphoria, stimulation, sedation, feelings of warmth, and in some cases, depression. As with all psychoactive substances, effects can very widely from person to person.
When taken as a tea, Kratom effects can be noticed in about 20 minutes. Generally, a feeling of stimulation and relaxation is noted, as well as a growing feeling of euphoria. Many become more sociable, and want to engage in conversation. In time, the stimulation fades and a strong sedation is noticed. This narcotic effect can be overpowering, and many will lay down and try to sleep. This can result in the waking dream state often times achieved by opiates. These effects can, in all, last between 2 to 5 hours. Extracts tend to take longer to take effect if they are eaten, but the effects can be noticed for a longer period of time.
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Links
Kratom.net Informational site on Kratom
Go to the ethnobotanicals forum Ethnobotanicals forum of www.drugs-forum.com
Go to the Kratom forum Kratom forum of www.drugs-forum.com
Erowid - Kratom Kratom vault of erowid
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