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a-PVP

a-PVP is a powerful synthetic stimulant drug which functions as a norepinephrine-dopamine reuptake inhibitor (NDRI), being roughly a quarter the potency of MDPV the effects are said to be comparable.

Contents




[top]Introduction to a-PVP

a-PVP, α-Pyrrolidinopentiophenone is an alkaloid in the pyrrolidine and ketone chemical classes, functioning as a norepinephrine-dopamine reuptake inhibitor (NDRI) and acting as a stimulant on the central nervous system and cardiovascular system. a-PVP was developed in the 1960 and has been available on the research chemical market for several years now, and is used as a recreational drug.


[top]Using a-PVP

[top]Ways of Administration

a-PVP can be administered orally, sublingually, rectally, intravenously, intramuscularly, insufflated, and inhaled with varying doses according to the route of administration. There is a great tendency to redose with this compound which is dependent on the route of administration, care should be taken, as it is suggested not to dose more then once an hour.

[top]Effects of a-PVP

Positive
Euphoria
Stimulation
Concentration (Dose dependent)

Negative
Anxiety
Paranoia
Psychosis
Muscle Tension
Vasoconstriction
Tachycardia

[top]Dosing of a-PVP

Intravenous
Threshold1-5mg
Low5-15mg
Moderate15-25mg
High25-35mg
Very High35-45mg


Insufflation
Threshold1-5mg
Low5-20mg
Moderate20-30mg
High30-40mg
Very High40-60mg

Oral
Threshold1-5mg
Low5-25mg
Moderate25-45mg
High45-70mg
Very High75-100mg

Vaporized
 
Low
Moderate
High
Very high
(Note: vaporization dose is very subjective due to high tendency to frequently redose. This represents one dose only.)


[top]Chemistry of a-PVP

Systematic(IUPAC) name:(RS)-1-phenyl-2-(1-pyrrolidinyl)-1-pentanone
Synonyms:alpha-Pyrrolidinovalerophenone, O-2387, alpha-PVP, 1-Phenyl-2-(pyrrolidin-1-yl)pentan-1-one
Molecular Formula:C15H21NO
Molar mass: 231.333 g/mol
CAS Registry Number:14530-33-7
Melting Point:96.11 C
Boiling Point:340.8 C at 760 mmHg
Flash Point:119 C
Solubility (HCl):~10 mg/ml in PBS (pH 7.2); ~20 mg/ml in EtOH; ~10 mg/ml in DMSO; ~3 mg/ml in DMF

MSDS Downloadable .pdf
Attachment 30859


[top]Appearance of a-PVP

A-PVP often comes in either a white, tan, or a yellowish powder, it is also available in very small white crystals. The difference in color is unknown, however the crystals are said to have a different effect then the powder.


[top]Legal Status of a-PVP

[top]United Nations

[top]USA

While not directly controlled in the United States A-PVP may be considered an analogue of MDPV thus falling under the Federal Analogue Act.

a-PVP is a Scheduled 1 substance in Delaware, Indiana, and New Mexico.

[top]EU

[top]Finland

Illegal in Finland since 2013.

[top]Other Countries




[top]References



Created by syntheticdave, 23-12-2012 at 20:10
Last edited by JTC3889, 05-05-2013 at 15:24
Last comment by fourtysevenpercent on 13-04-2013 at 11:53
4 Comments, 51,335 Views

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