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Zolpidem

Zolpidem, a sedative-hypnotic, is short acting and prescribed for the treatment of insomnia. Interacting with the GABA-BZ receptor complex and sharing some of the pharmacological properties of benzodiazepines. Zolpidem like most benzodiazepines can cause anterograde amnesia(forgetting the period during the effects)

Contents




[top]Introduction to Zolpidem



Zolpidem is sold under several brand names including Ambien, Ambien CR, Sublinox and Stilnox. Zolpidem’s main use is for the treatment of insomnia. Prescribed mainly as a short-acting hypnotic alternative to benzodiazepines it falls in the class of imidazopyridines which potentiate gamma-amino butyric acid. Zolpidem works quickly to bind to GABAA receptors at the same location as benzodiazepines (usually within 15 minutes). However due to its short half-life unless delivered in a controlled release form Zolpidem is not adequate in its effectiveness to maintain sleep.

[top]Ways of Administration


Zolpidem can be administered in several different ways. Two oral administrations one regular and one extended release version (Ambien and Ambien CR). Edluar and Intermezzo which are to be taken sublingually and come in sealed blister packs. And Zopimist which is an oral spray to applied into the mouth and over the tongue. The medication is to be taken as needed and not more than once per night. Food taken with Zolpidem may inhibit the speed and effectiveness of the drug.

[top]Effects of Zolpidem



As a member or this group I have taken a zolpidem 10mg tablet every night for over 6 months I don't sleep well and it is very effective for short acting sleep, less then 4 hours then I wake every hour on the hour don't know why................I don't abuse it or take more then prescribed I think maybe the CR 12.5 mg might work better as it's a controlled release thoughout the night however the drug is too expensive and just not available.

[top]Combinations with Zolpidem



[top]Different Uses for Zolpidem


Though there has been some evidence that Zolpidem has the possibility of working as an anticonvulsant or a muscle relaxant. The fact that results aren’t achieved until doses 20 to 30 times those required for sedation coupled with the fact that at those levels you are more inclined have one or more of the drugs adverse side effects Zolpidem has never been approved for such uses by the FDA

[top]Recreational Uses



Zolpidem has the possibility for misuse as a legitimate medication and as a medication used to get “High”. Medical misuse occurs when the drug is continued long term with or without a prescription. Recreational misuse tends to occur when physiological drug tolerance leads to inhalation, injection or taken for reasons other than medically approved for usually in amounts greater than 5-10 mg.
Users of stimulants have long been involved in the misuse of sedative/hypnotics such as Zolpidem as a way to come down or sleep after using methamphetamine or coke.
The drug seems to have a unique ability to elicit vivid visuals and body highs when the user resist the drugs hypnotic effects.


[top]Pharmacology of Zolpidem





[top]Legal Status of Zolpidem



[top]United Nations



[top]USA


Zolpidem is Schedule IV in the U.S. This means it is illegal to sell without a license and illegal to possess without a valid license or prescription

[top]EU


Zolpidem is available only with a prescription and is a Class C drug under the Misuse of Drugs Act.

[top]Other Countries



[top]More Zolpidem Sections





[top]The Latest Zolpidem Threads



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[top]References



Contributors: Alfa, Wanderer, Docta, makin
Created by makin, 21-08-2012 at 03:35
Last edited by Alfa, 18-11-2012 at 17:01
Last comment by Boltzmann on 07-11-2013 at 15:55
5 Comments, 16,019 Views

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