[top]Ways of Administration
Venlafaxine is prescribed for oral administration.
Recommended beginning daily dose of venlafaxine is 75mg, sometimes divided between two to three doses taken throughout the day, depending on your needs. Dosage may be increased in 75mg increments every four days. Extremely depressed patients may take up to 375mg/day in individual doses.
At low doses (<150 mg/day), it acts only on serotonergic transmission. At moderate doses (>150 mg/day), it acts on serotonergic and noradrenergic systems, whereas at high doses (>300 mg/day), it also affects dopaminergic neurotransmission.
[top]Physical effects of Venlafaxine
Venlafaxine is effective at treating the physical symptoms associated with depression, anxiety and panic disorders in some patients. It has also been found to be effective in the treatment of neuropathy and migraines.
Commonly reported physical side effects of venlafaxine include:
-asthenia
-sweating
-nausea
-constipation
-anorexia
-vomiting
-somnolence
-dry mouth
-dizziness
-tremor
-blurred vision
-abnormal ejaculation/orgasm and impotence in men
[top]Psychological effects of Velafaxine
Venlafaxine is effective at relieving the psychological symptoms associated with depression, anxiety and panic disorders in some patients.
Commonly reported adverse psychological side effects of venlafaxine include:
-nervousness
-anxiety
[top]Combinations with Venlafaxine
Venlafaxine should also not be combined with other serotogenic drugs to include MAOIs, SSRIs, SNRIs,
psychedelic typtamines (
DMT,
LSD, etc.), psychedelic phenylethylamines (
MDMA,
mescaline, etc.),
tramadol, and
dextromethorphan (
DXM) as it may result in a serious and potential lethal interaction known as
serotonin syndrome. Velafaxine therapy should be terminated at least seven days prior to the administration of another serotogenic
drug.
Use of venlafaxine with other amphetamine-like drugs is discouraged by the manufacturer.
[top]Different Uses for Velafaxine
Venlafaxine is used for the treatment of:
-Major Depressive Disorder
-Generalized Anxiety Disorder
-Panic Disorder