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Triazolam

Triazolam A drug from the Benzodiazepine group is used as a short term treatment for insomnia and other sleep related disorders. The drug works by retarding brain activity.

Contents




[top]Introduction to Triazolam

Also known by trade names Halcion and Trilam, it possesses pharmacological properties similar to that of other benzodiazepines, but it is generally only used as a sedative to treat severe insomnia.

Triazolam has been known to exhibit a wide range of effects: Hypnotic, Sedative, Anticonvulsant, Amnesic, muscle relaxant and Anxiolytic. One of the fastest acting benzodiazepines in the group it also has one of the fastest clearance rates (1-2 hour Half-Life) making it an ideal sedative and sleep aid for air travel. These properties generally negate the morning drowsiness associated with the benzodiazepine group.

Warning Triazolam is Pregnancy Category X
This drug is known to have the potential to cause birth defects.


[top]Using Triazolam

[top]Ways of Administration

[top]Effects of Triazolam



[top]Pharmacology of Triazolam


LD50 (mg/kg) [1] :
Mice : >100 orally
Rat : >5000 orally


[top]Chemistry of Triazolam

Systematic(IUPAC) name:8-chloro-6-(2-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
Synonyms:8-chloro-6-(o-chlorophenyl)-1-methyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine, clorazolam, U-33030, Halcion, Songar, Trilam, Hypam, Apo-Triazo, Chlorazolam
Molecular Formula:C17H12Cl2N4
Molar mass:343.21 g/mol [2]
CAS Registry Number:28911-01-5
Melting Point:233-235℃
Boiling Point:no data
Flash Point:no data
Solubility:Soluble in chloroform; slightly soluble in alcohol; practically insoluble in ether and in water
Additionnal data:none
Notes:Aspect : tan crystals; crystallized from isopropanol
[2]


[top]The Dangers of Triazolam

Pregnancy Category X: This drug is known to have the potential to cause birth defects.


[top]Legal Status of Triazolam

[top]United Nations

[top]USA

[top]EU

[top]Other Countries




[top]References


[1]Merck Index, fifteenth edition (2013)
[2]Calculated from Atomic Weights of the Elements, 2007


Created by LifeSucceedsDeath, 05-02-2013 at 05:48
Last edited by John_bob, 10-05-2014 at 11:45
Last comment by Docta on 14-03-2013 at 09:37
2 Comments, 6,321 Views

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