Take this medicine as indicated by your physician.
[top]Ways of administration
[top]Effects of Oxymorphone
[top]Combinations with Oxymorphone
Below are noted drug interactions with Opana as specified by manufacturer Endo Pharmaceuticals
• CNS depressants
: Increased risk of respiratory depression, hypotension, profound sedation, coma or death when combined with OPANA ER. When combined therapy with CNS depressant is contemplated, the dose of one or both agents should be reduced.
• Mixed agonist/antagonist opioids
(i.e., pentazocine, nalbuphine, and butorphanol): May reduce analgesic effect and/or precipitate withdrawal
• Cimetidine: Combination use with OPANA ER may precipitate confusion, disorientation, respiratory depression, apnea, seizures.
• Anticholinergics: Concurrent use with OPANA ER may result in urinary retention and/or severe constipation, which may lead to paralytic ileus.
• Monoamine oxidase inhibitors
(MAOIs): Potentiate the action of opioids. OPANA ER should not be used in patients taking MAOIs or within 14 days of stopping such treatment.
Extreme caution should be used when Opana is taken in combination with the following drugs;
- when combined with Opana will cause further depression of the respiratory system and CNS which can increase the chance of loss of consciousness, seizure, death etc.
) - when combined with Opana will cause further depression of the respiratory system and CNS which increases the chance of injuries, seizure, death, blackouts etc.
- Barbituates - when combined with Opana will cause further depression of the CNS. Increasing the chances of injuries and fatalities.
**If possible the use of the above drugs should be avoided while on Opana to ensure the most harm prevention.
[top]Different Uses for Oxymorphone