
LSA (d-lysergic acid amide, ergine) is a psychedelic ergoline alkaloid closely related to LSD. An LSA experience is characterized by effects similar to those of LSD, for example auditory and visual hallucinations, spatial and temporal distortion, introspection, etc. It is a powerful psychedelic (roughly one-tenth the potency of LSD, with a threshold dose of ~500 micrograms), however the most common form of administration is an extraction made from
Ipomoea tricolor (Morning glory) or
Argyreia nervosa (Hawaiian baby woodrose) seeds; this often produces a pronounced body load (nausea associated with chemically treated seeds), resulting in an experience that is less intense than LSD as a result of the experience being overpowered by the body load and/or a low amount of alkaloids present in the extract.
Rivea corymbosa seeds have been used for spiritual purposes by natives of Mexico for centuries, known there by the name
ololiuhqui. LSA was bioassayed for the first time in 1947 by Dr. Albert Hofmann, about a decade before it was discovered to be produced naturally by certain plants.