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[top]Introduction to 4-FA


4-fluoroamphetamine acts as both a releasing agent and reuptake inhibitor of dopamine, serotonin, and norepinephrine.


[top]Using 4-FA

[top]Ways of Administration

The two most common routes of administration for 4-FA are intranasal and oral consumption, with oral consumption being the primary route of administration among researchers, due to the rather painful burning sensation that is accompanied with intranasal administration.

[top]Oral use of 4-FA

[top]Nasal use of 4-FA

[top]Anal use of 4-FA

[top]Smoking 4-FA

[top]Effects of 4-FA

[top]Positive

  • Euphoria
  • Increase in energy (stimulation)
  • Increased awareness of senses
  • Increased appreciation for music
  • Feelings of love and empathy

[top]Neutral

  • Loss of appetite
  • Mild visual hallucinations
  • Restlessness
  • Increased perspiration
  • Changes in body temperature regulation
  • Increased sensitivity to light

[top]Negative

  • Tachycardia
  • Anxiety or paranoia
  • Agitation
  • Clenching of the jaw (bruxism)
  • Difficulty concentrating
  • Insomnia
  • Nausea and vomiting

[top]Combinations with 4-FA

[top]Different Uses for 4-FA



[top]Pharmacology of 4-FA

4-fluoroamphetamine is a release agent and reuptake inhibitor of dopamine, serotonin, and norepinephrine. The respective EC50 values are 2.0 x 10−7 M, 7.3 x 10−7 M, and 3.7 x 10−8 M, while the IC50 values are 7.7 x 10−7 M, 6.8 x 10−6 M, and 4.2 x 10−7 M.[1]

Regarding the metabolic fate of 4-FA, it is likely excreted from the body entirely unchanged. The C-F bond at the 4-position on the phenyl ring likely resists deactivation in the liver by cytochrome P450 oxidase[2]


[top]Chemistry of 4-FA

Systematic (IUPAC) Name(RS)-1-(4-Fluorophenyl)propan-2-amine
SynonymsPhenethylamine, p-fluoro-a-methyl-(7CI,8CI), p-Fluoroamphetamine, Benzeneethanamine, 4-fluoro-a-methyl-, 4-FA
Molecular FormulaC9H12FN
Molar Mass153.20
CAS Number459-02-9
Flash Point93.6 C
Boiling Point215.2 C at 760 mmHg


[top]The Dangers of 4-FA



[top]Producing/Growing 4-FA



[top]Forms of 4-FA



[top]Legal Status of 4-FA

[top]United Nations

[top]USA

4-FA is unscheduled in the United States, however it may be considered an analog of PMA, in which case it may be prosecuted under the Federal Analog Act if intent for human consumption is present.

As of 7/1/12, 4-FA is a schedule 1 substance in the state of Virginia.

[top]EU

As of 1/1/2012 4-FA is illegal to possess, buy, or sell in Germany.

Illegal in Finland since 2011.

[top]Other Countries

[top]Israel

4-FA was added to Israel's list of controlled substances in December of 2007, making it illegal to possess, buy, or sell.

[top]Poland

4-FA is a controlled substance in poland.

[top]Slovak Republic

As of March 1, 2011, Spice-type cannabinoid receptor agonists, 4-Fluoroamphetamine, MDBD, bk-MBDB, bk-MDMA, and 4-Methylmethcathinone are to be considered controlled substances in the Slovak Republic.

[top]United Kingdom

4-FA is considered to be a Class A drug under the Misuse of Drugs Act.


[top]Images of 4-FA



[top]History of 4-FA

Popularity of 4-FA over time:



[top]More 4-FA Sections



[top]The Latest 4-FA Threads


  Article / Page Starter Last Post Comments Views
Ilsa
19-04-2014 12:37
by John_bob Go to last post
8 12,103
Alfa
18-04-2014 10:22
by Alfa Go to last post
24 279,226
Calliope
14-04-2014 15:12
by M0RPH3US Go to last post
7 45,063
JustKeepSwimmin
13-04-2014 06:44
by Stimulants Go to last post
14 12,653
syntheticdave
12-04-2014 22:03
by Szandbwoy Go to last post
4 1,654
Joe-(5-HTP)
10-04-2014 04:26
by syntheticdave Go to last post
5 138,921
Alfa
06-04-2014 18:33
by John_bob Go to last post
1 6,433
Wanderer
04-04-2014 17:01
by Alfa Go to last post
2 4,521
Wanderer
04-04-2014 16:58
by Alfa Go to last post
9 10,913
Alfa
02-04-2014 21:13
by John_bob Go to last post
16 171,460


[top]References

  1. ^ http://www.unc.edu/~dlinz/Papers/The%20effects%20of%20non-medically%20used%20psychoactive%20drugs%20on%20mon oamine%20neurotransmission%20in%20rat%20brain.pdf
  2. ^ http://www.ncbi.nlm.nih.gov/pubmed/16445122


Created by Wanderer, 14-01-2012 at 04:00
Last edited by anj0vis Gold member, 31-01-2014 at 10:07
Last comment by Bass_spacecase1 on 08-01-2014 at 03:58
9 Comments, 15,578 Views

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4-fa, 4-fmp, amphetamines, halogenated amphetamines, research chemicals
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