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Research Chemicals Piperazines, Phenethylamines, Tryptamines & other Research Chemicals or designer drugs.

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  #1  
Old 07-07-2005, 16:06
joachimist joachimist is offline
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2-methylamino-1-</span>(3,4-methylenedioxyphenyl)butan-1-</span>one



and what is the DOSAGE (oral...) and DURATION???



i tried to search for info but i couldn't find anything (pikhal, erowid, lycaeum,....)





Is it the same as Methylone ?



The butane instead of propane... does it makes differences ?


Edited by: _jo_

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  #2  
Old 07-07-2005, 16:18
joachimist joachimist is offline
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or is it MDBD ? but the -1-one should make it different ?





and i also wondering what are those molecules :



1-(4-fluorophenyl)propane-2-amine



1-(3,4-methylenedioxy-phenyl)-2-pyrrolidin-1-yl-pentan-1-o ne


Edited by: _jo_
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  #3  
Old 07-07-2005, 18:15
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methyl jones, or mebylone I think. the -1-one indicates a double bonded oxygen or ketone group.
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Old 07-07-2005, 18:19
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1-(3,4-methylenedioxy-phenyl)-2-pyrrolidin-1-yl-pentan-1-o ne


this would presumably be a pyradine-like(structurally related to benzene) ring with a ketonatedamyl hydride bit coming offtrying to mimicthe carbon stringstructure of an amphetamine, all with a classic PEA/amphetamine carrier structure.I would NOT want to be the first to try this substance.Edited by: allyourbase
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  #5  
Old 07-07-2005, 23:29
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it's not very helpful to spread these nicknames before the substance
hasnt gained any popularity. and since it probably never will one
shouldnt start giving misleading nicknames to it.

call it the beta-keto analog of mbdb if you want.



the last one shouldnt be very potent because of its long sidechain. i
think i read in pihkal that they dont seem to have any activity. but i
dont know what the pyrrolidin-ring alters, it's located around the
nitrogen afaik.


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  #6  
Old 08-07-2005, 02:00
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yes pls stay away from nicknames as descriptives.
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Old 08-07-2005, 03:23
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As far as I know, no one on this forum has yet tried any of those
compounds. Here's some info from another forum:

Quote:
Originally Posted by C6H6
There's a fair bit of SAR data in the patent literature for
3,4-methylenedioxy- and 4-methoxyphenylaminoketones. There seems
to be a trend that lengthening the keto-chain up to 5 carbons and the
amine substituent up to three carbons each increases the potency.

So the two new compounds may well be more potent than methylone. The
therapeutic index, as measured by the ratio between LD50 and ED50 for
psychostimulation in the mouse is rather high for such compounds, in the
range of 70 - 175. However, the available data cover mainly
butyrophenone and valerophenone derivatives. Apparently,
propiophenone derivatives (methylone 100 - 200mg) were considered too
low in potency or otherwise undesirable.

My theory is that the longer the chain(s), the more selective these
compounds become for DA reuptake inhibition, relative to 5-HT and NE
reuptake inhibition. At the extreme end is 3',4'-methylenedioxy-2-
pyrrolidin-1-yl-valerophenone (MDPV), which is a pure stimulant at a
human dose of about 5mg. It's the most potent stimulant in this class,
and the relatively least toxic.

It's similar to methylphenidate and has no serotonergic/entactogenic
properties. It's therapeutic index is 875, compared to only 42 given by
the same authors for amphetamine, and it's about 10 times as potent as
amphetamine in the mouse. It's a real bargain considering that you get
200 doses out of 1g.
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  #8  
Old 08-07-2005, 11:06
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Ok thank every body... I was actually looking for nicknames because i'm
used to read trip-reports before try products, and i couldn't find
anything about those. Now i can, thanks.

I understand nicknames can be problematic for such unknown RCs...



i still have a question for you:

1-(4-fluorophenyl)propane-2-amine

is it 4-FMP ??


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  #9  
Old 08-07-2005, 11:14
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no,
1-(4-fluorophenyl)propane-2-amine is 4-FA (4-fluroamphetamine)
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  #10  
Old 08-07-2005, 18:55
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Unfortunately, the name "4-FMP" has gotten tagged onto this drug, even
though it is incorrect.
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  #11  
Old 14-07-2005, 06:22
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Quote:
Originally Posted by radiometer
Unfortunately, the name "4-FMP" has gotten tagged onto this drug, even
though it is incorrect.
what is the differance between real 4-FMP and the above mentioned chemical? what are the differance in effects?

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  #12  
Old 14-07-2005, 09:09
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Quote:
Originally Posted by pinkavvy
Quote:
Originally Posted by radiometer
Unfortunately, the name "4-FMP" has gotten tagged onto this drug, even

though it is incorrect.


what is the differance between real 4-FMP and the above mentioned chemical? what are the differance in effects?




I wasn't aware there was a "real" 4-FMP, but rather that the name 4-FMP
was just not technically a very good abbreviation (I guess it stands
for 4-Fluoro-alpha-Methyl-Phenethylamine). Same chemical, AFAIK.

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  #13  
Old 15-07-2005, 00:50
JewishNazi JewishNazi is offline
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Hmm, strange that it would be given the 'wrong' name.


Irrigardless of the topic, I thikn it would be MDPPP as an abreviation because those are the letters that each main part starts with
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  #14  
Old 15-07-2005, 00:57
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I forget where I read about it, the story is that a vendor used that name
and it stuck.
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Old 20-07-2005, 14:46
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The compound mentioned originally, i.e. the MBDB/Methyl-J homologue of methcathinone</span>, has been referred to as Mebylone</span>, Methyl-Jones</span>, and Butylone</span>
in various posts and by various persons. I do agree that it is
unwise to tack nicknames onto substances before they are thoroughly
researched, and even then giving a substance a nickname can
occasionally create a force of suggestion or an aire of implied effects
that taints the subjective bioassay, and often leaves the experimenter
confused and/or disappointed. Think of all the folks that tried
"foxy" (5-MeO-DIPT), and then got pronouced nausea followed by the
shits for a few hours.



What's the appropriate web-chat abbreviation to be used here? Oh yeah-- Y</span>our M</span>ileage M</span>ay V</span>ary (YMMV).



Also-- "MDPPP" is IMO just a bit too reminiscent of MPPP and
MPTP, which were the fucked-up merperidine analogues that caused all
those sudden outbreaks of instant Parkinson's disease in the
mid-1980's, prompting the hysterical knee-jerk media term "designer
drugs" and helping to encourage the passing of the Controlled Substance
Analogue Act (CSAA) by congress.

Either that, or it sounds like another piperazine compound, like TFMPP or PMMBP. Just my opinion though.


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Edited by: Eirias
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  #16  
Old 20-07-2005, 15:02
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http://www.erowid.org/experiences/exp.php?ID=44549
Quote:
[Erowid Note: 2-methylamino-1-(3,4-methylenedioxyphenyl)butan-1-one is the beta-ketone analogue of MBDB. Shulgin suggests the name 'Butylone' for this compound.]
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Old 21-07-2005, 02:28
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is this case, Shulgin would have to be wrong. 'Butylone' makes it sound as if it has a mutylene groupbecause of the similarity to methylong and ethylon. There will obviously be confusion due to that. methylJones is the best so far
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Old 24-07-2005, 20:48
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Or perhaps methyljone, as the the plural is probably amusing rather than necessary? MBDBone might be as approproriate, as Shulgin called MBDB Metyhl-J to avoid the stigma of MDMA.
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Old 15-08-2005, 18:15
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Regarding
1-(3,4-methylenedioxy-phenyl)-2-pyrrolidin-1-yl-pentan-1-o ne:



Quote:
Originally Posted by JewishNazi


Irrigardless of the topic, I thikn it would be MDPPP as an
abreviation because those are the letters that each main part starts
with


I posted this on another forum and will repost because it exactly applies here:



WARNING! The name "MDPPP</font>"
has been applied to two different compounds. One of them has been
discussed in this thead, and is also known as MDPV, aka
1-(3,4-methylenedioxy-phenyl)-2-pyrrolidin-1-yl-pentan- 1-one, aka
3',4'-methylenedioxy-2-pyrrolidin-1-yl-valerophenone. This is a ketone
with a five-carbon chain.



However, there is also a similar compound, chemically identical except
for the fact that it has a three-carbon chain. Its chemical name is
3',4'-methylenedioxy-alpha-pyrrolidinopropiophenone.

Link: http://amphetamines.com/mdppp/



The confusion results from the fact that propane (3 carbons) and
pentane (5 carbons) both begin with the letter "p". The name MDPV is
pretty umambiguous because the "v" stands for "valerophenone", another
name for "pentanophenone".



These compounds likely have different dosages. The five-carbon
compound, MDPV, is reportedly active at just 5 mg. I have no
information as to the activity of the three-carbon compound.



Be sure you know which one you're working with!</font>

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Edited by: gn2osis
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Old 20-09-2005, 08:02
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this would presumably be a pyradine-like(structurally related to benzene) ring with a ketonatedamyl hydride bit coming offtrying to mimicthe carbon stringstructure of an amphetamine, all with a classic PEA/amphetamine carrier structure.I would NOT want to be the first to try this substance.That's a mixture of gobbledegook and plain incorrect. It has nothing to do with pyridine (which is a heterocyclic six membered aromatic compound). It refers to pyrrolidine, which is aheterocyclic fivemembered non-aromatic compound. As to what a ketonated amyl hydride is, god alone knows. The compound is a ketone with a substituted benzene ring (sub with 3,4-methylenedioxy group) on one side of the carbonyl group, and a butyl chain, with a pyrrolidine ring attached via the nitrogen to the carbon adjacent to the carbonyl group. It is vaguely a modified amphetamine structure (very vaguely) that is a specific dopamine reuptake inhibitor, active in humans at around the 5mg mark, orally
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