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Cannabinoids Cannabinoids & smoking blends.

 
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  #1  
Old 24-07-2009, 17:28
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Research Chemicals Index - Synthetic Cannabinoids

Synthetic cannabinoids are a structurally diverse group of compounds that act as cannabinoid receptor agonists. Some of these compounds produce intoxicating effects similar to those of the phytocannabinoids found in plants of the genus Cannabis, while others produce varying levels of euphoria, intoxication and analgesia. Despite their functional homology, many research chemicals of this class bear little structural resemblence to naturally occurring cannabinoids. Synthetic cannabinoids are typically active in the very low milligram range and either smoked (alone or as part of a smoking blend mixture) or taken orally. Given the potency of these compounds, use of appropriate weighing apparatus is essential to minimize the risk of overdose.

Please help to expand our understanding of this class of psychoactive substances by contributing to the threads highlighted below, and recognizing posters that have made useful contributions by awarding positive reputation.

Cannabinoid
Drug Info
Drug Experiences
Tagged Threads
Documents
Image Gallery
JWH-018
JWH-073
JWH-081
JWH-200
JWH-250
AM-694
CP-47,497
CP-55,940
HU-210
WIN-55,212-2
JWH-007
JWH-015
JWH-017
JWH-019
JWH-203
JWH-203 Info
JWH-203 Experiences
JWH-210
JWH-307
JWH-398
JWH-398 Info
JWH-398 Experiences
AM-2201
AM-2201 Experiences
CB-25
CB-52
SR-18*
SR-18 Experiences

* Note: SR-18 is a colloquial term for this compound and does not appear in any patent documentation or peer reviewed scientific literature. This compound is a close homologue of the better characterized compound JWH-250.

______________________________________

Related Research Chemical Indices:

Phenethylamine RC Index
Tryptamine RC Index
Piperazines RC Index
Miscellaneous RC Index
Unidentified RC Products Index

Post Quality Evaluations:
Excellent compilation of the information within this forum.
valuable summary of different cannabinoids
Bullseye information.
Great resource! Thank you
very detailed info, great post!
Really good thread. I can see that a ton of work went into it. I Wish I could give more than 4 points. This deserves it.
Greatly informative, much easier for the rest on the forum to find info in one place. Great job

Last edited by Phenoxide; 12-10-2010 at 20:48. Reason: big index update
  #2  
Old 23-10-2009, 04:01
osirisx osirisx is offline
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Re: Research Chemicals Index- Cannabinoids

JWH-007
JWH-122
jwh-133
AM -630
AM-694
AM-1241
  #3  
Old 23-10-2009, 17:07
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Re: Research Chemicals Index- Cannabinoids

JWH-122 is mentioned in "The Cannabinoid Receptors", by Patricia H. Reggio- noted as having a very high affinity (Ki of 0.69 +/- 0.05 nM) for the CB1 receptor. This is the only place in which this compound appears outside of the Huffman papers.
  #4  
Old 19-06-2010, 07:21
Drats Gold member Drats is offline
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Re: Research Chemicals Index- Cannabinoids

SWIM tried to use the search engine and Google, but did anyone found an experience report with JWH 122 or JWH 210? The substances are getting available through several vendors, so SWIM is concerned about the high affinity, which would indicate the dosage is extremly low and the risk of overdosages are extremly high. Also no information could be found on duration and else.
  #5  
Old 12-10-2010, 20:50
Phenoxide Phenoxide is offline
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Re: Research Chemicals Index- Cannabinoids

The index at the top of this thread has now been updated to include discussion of cannabinoids that has occurred since the last update 12 months ago. Please contribute to the highlighted threads and also help to keep this index up-to-date by highlighting new drug information and experience threads as they arise.
  #6  
Old 14-11-2011, 13:41
jeremysdemo jeremysdemo is offline
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Re: Research Chemicals Index - Synthetic Cannabinoids

is there any way to get an analog map or diagram here of these?

for example JWH-081 is an analog of JWH-018.

jerm
  #7  
Old 14-11-2011, 16:59
Phenoxide Phenoxide is offline
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Re: Research Chemicals Index - Synthetic Cannabinoids

Simply put no. Analogue law is deliberately vague and therefore left open for interpretation by the courts. There is no definitive mapping of 'X is legally considered analogous to Y' because of this ambiguity. The definition of analogue will also vary by jurisdiction (if a definition is even offered at all). If a compound shows cannabinoid receptor activity and has recreational psychoactive effects then a case for analogy in the broadest sense could always be made.
  #8  
Old 15-11-2011, 16:19
jeremysdemo jeremysdemo is offline
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Re: Research Chemicals Index - Synthetic Cannabinoids

Quote:
Originally Posted by Phenoxide View Post
Simply put no. Analogue law is deliberately vague and therefore left open for interpretation by the courts. There is no definitive mapping of 'X is legally considered analogous to Y' because of this ambiguity. The definition of analogue will also vary by jurisdiction (if a definition is even offered at all). If a compound shows cannabinoid receptor activity and has recreational psychoactive effects then a case for analogy in the broadest sense could always be made.
most of the cases I have been following are using the analog law for substances with "structural similarity".

if the government paid PHD's can look at them and determine that from their molecular shape I'm sure people in the private sector have the ability too.

jerm
  #9  
Old 15-11-2011, 16:46
Phenoxide Phenoxide is offline
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Re: Research Chemicals Index - Synthetic Cannabinoids

You don't seem to comprehend what I am saying. "Structural similarity" is a not a well defined chemical term. It is not a magical definition that all chemists immediately reach a consensus upon. I could draw up a far from complete list of what I consider to be structural analogues (both known and theoretical) of substance X, but my list wouldn't necessarily match those of other chemists, and more importantly it may not match the interpretation of the courts. Such a list would therefore create false assurances over the legal status. It's open to interpretation and the courts have the final say on the matter. There is no "right" answer.

If there was a definitive answer to what you're asking for then analogue law would be without purpose. It exists is to create this ambiguity and thereby gives the courts some flexibility to prosecute where they know an individual is skirting the law (and let's face it, they know the "designer drug" trade isn't legitimate) but would otherwise get by on a technicality. The reach of analogue law only becomes clear when it is tested in the courtroom. Anything before that stage would be speculation.

Let's not forget that the courts are also mindful of intent. In the context of an unregulated, untested chemical being obviously sold for human consumption (no matter how it is packaged), the courts are likely to side with the prosecution if they have even a weak case for analogy. Such a case could be easily created for most of the cannabinoids being analogous to something on the controlled substances list of the state or federal government.
  #10  
Old 13-04-2012, 02:16
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Re: Research Chemicals Index - Synthetic Cannabinoids

So are blend producers just playing roulette with the cops. Have talked to several shops in Texas and have a intrested group, but concerned with the laws. Seems the analog act is a catch all.
  #11  
Old 27-02-2013, 17:35
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Re: Research Chemicals Index - Synthetic Cannabinoids

I'v gone about to create a new table, containing 32 additional cannabinoids which at the time of the original post had either not yet been marketed or synthesized. The table below contains all of the cannabinoids mentioned in the original post, with some of the links being updated.

Enjoy
SyntheticDave

Cannabinoid
Drug Info
Drug Experiences
Tagged Threads
Documents
Image Gallery
2NE1
2NE1 Experiences
A-834,735
A-834,735 Experiences
A-836,339
A-836,339 Experiences
AB-001
AB-001 Experiences
AB-034
AB-034 Experiences
AKB48
5F-AKB48
AKB-NI
AKB-NI Experiences
AM-694
AM-1248
AM-2201
AM-2233
BAY 38-7271
BAY 38-727 Experiences
BB-22
BB-22 Experiences
CB-25
CB-52
CP-47,497
CP-55,940
EAM-2201
HU-210
JTE-907
JTE-907 Experiences
JWH-007
JWH-015
JWH-017
JWH-018
JWH-019
JWH-022
JWH-022 Experiences
JWH-030
JWH-030 Experiences
JWH-073
JWH-081
JWH-122
JWH-147
JWH-147 Experiences
JWH-182
JWH-182 Experiences
JWH-200
JWH-203
JWH-210
JWH-250
JWH-251
JWH-307
JWH-370
JWH-370 Experiences
JWH-398
JWH-398 Experiences
MAM-2201
MN-25
MN-25 Experiences
NNE1
NNE1 Experiences
PB-22
5F-PB-22
RCS-4
RCS-4 Experiences
SR-18
SR-18 Experiences
STS-135
STS-135 Experiences
UR-144
5F-UR-144
URB-597
URB-754
URB-754 Experiences
WIN-55,212-2
***Thread Not Yet Created

Post Quality Evaluations:
Fantastic job updating this listing.
Great work. It will be good to see it completed.
Great effort
Excellent work mate

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am-2201, cannabinoid, cannabinoid research, cannabinoids, jwh-018, research chemical index, research chemicals, synthetic cannabinoids, synthetic drugs, synthetic marijuana

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