Combinations - Codeine plus visteril- no effect?

[kuf66ver]

Swim took three tylenol 3's and a visteril and felt nothing. Everyone swim knows takes 2 T3's and the visteril and says its comparable to morphine, but swim feels nothing. Swim has also tried xanax, hyrdrocodone, and darvocet and found that even doses 3-4x the recommended amount do nothing to him.

Is there something swim can do to feel a buzz from these drugs? Is it possible for certain drugs to not work on a person's body? Swim tried smoking weed with the codeine pills but got nothing more than the normal marijuana high. Swim has only used painkillers a handful of times in his life and never gets high...

[miggeth]

Originally Posted by kuf66ver

Is it possible for certain drugs to not work on a person's body?

Yes, the effectiveness of codeine depends on an enzyme in the liver, which converts it into morphine. Until this happens codeine is inactive in the body. This enzyme activity varies a lot from person to person, and is sometimes comletely absent. This is why different people have such different experiences with codeine, and why for some people, it will never do anything for them.

It's about 2% of people who don't have this enzyme swim believes.