this has been on SWIMS mind for a while, actually. he recently (after a string of poor decisions) severely lacerated his foot and was prescribed a good amount of tylenol 3's (30 mg codeine to 300 mg APAP). What he didn't find out until later, though, was that the pills he received actually contain, and i'm not sure about the exact amount, 15mg of caffeine. He thinks it's because tylenol 3's are commonly given for migraines, and caffeine works against headaches.
anyway, he noticed when dosing that he really only felt the drug for no more than half an hour, and wondered if the caffeine wasn't to blame, as it does some work in speeding up metabolism.
what he's trying to say, then, is that maybe any potentiation from caffeine is just getting more of the drug quicker, as SWIM's metabolism is working faster.
this is all speculation, though, as he isn't a scientist, and hopes he isn't pretending to be one.
SWIM can't say coffee specifically but one of his favorite breakfasts used to be a snort or plug of hydromorphone with 3 NoDoz caffeine tabs and some grapefruit juice...something about that combo that made it wonderful to wake up to...
So not sure if coffee actually strengthens or not but definitely enhances....at least for SWIM...
That is possible. SWIM recalls many of the codeine preparations back in the 80's, 90's had some containing caffeine (counteract drowsiness perhaps?)
The original Percodan brand pills by DuPont\Endo had oxycodone, aspirin and caffeine as well. Most docs prescribe percocet or Tylenol w\codeine now days so those with any caffeine are rarer anyhow but still may be around