Drugs-Forum  
Home Wiki Studies Forum Groups Blog Video Images News
Go Back   Drugs Forum > DRUG-FORUMS > Research Chemicals > Cannabinoids
Mark Forums Read
Register Tags

Notices

Cannabinoids Cannabinoids & smoking blends.

 
Thread Tools
  #1  
Old 14-06-2009, 23:00
Ofiend Ofiend is offline
Account Awaiting Email Confirmation.
 
Join Date: 14-06-2009
52 y/o Male
Posts: 1
Ofiend is an unknown quantity at this point
Points: 9, Level: 1 Points: 9, Level: 1 Points: 9, Level: 1
Activity: 0% Activity: 0% Activity: 0%
CP47.497 toxicity and carcinogenity

As I see it, the psychedeli (producer of spice) has investigated the toxicity of JWH-018 in full ADME toxicity studies, posted here:
JWH-018 (Spice) ADME Toxicology Studies & Discussion

But CP47,497 is what is in spice gold, spice diamond, spice silver. Their jwh-018 products have been around since last year. CP47.497 has been around since 2004!!!!

So they surely must have studied its toxicity. But where is the ADME study?? I can't find it anywhere. If it is not published why not? Do you think the Psychedeli are hiding CP47.497 toxicity?

Is CP47,497 carcinogenic??
  #2  
Old 14-06-2009, 23:18
Valseedian Valseedian is offline
Silver Member
 
Join Date: 30-04-2009
Male from United States
Posts: 373
Valseedian is on the way upValseedian is on the way upValseedian is on the way upValseedian is on the way up
Re: CP47.497 toxicity and carcinogenity

swim has done quite a bit of pure cp-47497... he hasn't seen much info as far as the toxicity, and doubts seriously if there is any serious amount of this chemical on these blends. cp-47497 has about a 30% combustion rate in pure form thrown into a pipe. that is, he throws 3mg into a pipe, and takes a decent pull (3 seconds or so).. holds that in for around 8-10 seconds... after you exhale it feels almost as if you'd been inhaling burning plastic... my lungs feel 'sticky', and very (very) mild nausea comes on for about 30 seconds. after which feeling returns to normal and a 'stoneyness' rushes over him.. about 1mg is 'consumed' this way. bowl is cleaned with acetone and collected/scraped for the future between sessions.

cp-47497 can last as long as 7 to 10 hours depending on dose and redose, and tends to put swim to sleep.
tollerance to cp-47497 seems to fade after no more than 36 hours of non-exposure, and the longer you've been off of marijuana, the heavier cp will hit. (this has something to do with thc's metabolites' being mitigating and the fact that CBD helps to controll the activity of THC's)

CP tollerance does NOT seem to effect THC tollerance in the long term.


swim replaced marijuana with cp-47497 for a week, gathered a tollerance to cp-47497 that caps at around day 5... a 36 hour break seems to nullify all tollerance to cp-47497.

Smoking is not the most favorable ingestion method for this drug. Swim find that 4mg capsules or 2mg insuflated can have actions as long as 18 hours without having to re-dose, but doses lower than that weren't active.


swim wanted to attempt an IV injection of cp-47497, but is reluctant to do so because of lack of experience with needles, and the fact that cp doesn't desolve into water at all...
  #3  
Old 15-06-2009, 19:15
nibble nibble is offline
Titanium Member
 
Join Date: 10-02-2008
Male from Ireland
Posts: 466
nibble probably knows what they are talking about.nibble probably knows what they are talking about.nibble probably knows what they are talking about.nibble probably knows what they are talking about.
Points: 552, Level: 3 Points: 552, Level: 3 Points: 552, Level: 3
Activity: 0% Activity: 0% Activity: 0%
Re: CP47.497 toxicity and carcinogenity

The reason JWH-018 and some others in the series were marked as possible carcinogens was due to the naphthalene ring system in their structure, such compounds have been shown to be potential mutagens. CP47,497 does not possess any such properties that would indicate toxicity, it is much closer to a classical cannabinoid than the novel structure of the JWH's. The ADME test was useful for JWH-018 as it had never been developed as a pharmaceutical drug and as such never underwent any toxicity studies. It was never designed with consumption in mind so any long term health implications would not have been of concern anyway.

CP47,497 was developed but never marketed as a pharmaceutical by Pfizer in the eighties, it would have passed some initial testing and developed with ultimate human consumption in mind.
In short I could not foresee any major health implications beyond those of Δ9-THC with this, it is close enough in structure and doesn't seem to have any other notable interactions.

Just wanted to add that this should not be administered by IV injection Valseedian. For water insoluble non salt forming compounds like this you must prepare a special emulsion in order to go that route and that is beyond the average persons capacity.

Last edited by nibble; 15-06-2009 at 19:30.

Share this on:

Tags
497, cp-47, cp-47 497, cp-47.497, cp47.497, drug, drugs, drugs forum, health, jwh, jwh-018, pfizer, spice, spice diamond, spice gold, spice health effects, spice health risks, spice smoking blend

Thread Tools


» New Threads
Dexedrine, anti-anxiety and...
Last post by Giapsufsu
2 Replies, 108 Views
Do you think I'm going to have a...
Last post by Giapsufsu
1 Replies, 69 Views
Havent slept in 50 or so hours,...
Last post by Giapsufsu
1 Replies, 33 Views
FAB-144/ FAB144 Drug Info
Last post by Soulfake
2 Replies, 1,803 Views
advice, pain management pricks...
Last post by Safira
2 Replies, 71 Views
Rand Paul Files Asset Forfeiture...
Last post by Name goes here
3 Replies, 91 Views
Lsd ultimate aim?
Last post by RealMartinKeller
1 Replies, 62 Views
Took 300mg DPH (1st time), and......
Last post by Tulio_Hermil
5 Replies, 156 Views
Heroin; I really need some...
Last post by Window Ninja
208 Replies, 10,742 Views
researching item #2 on my list...
Last post by Tulio_Hermil
2 Replies, 76 Views
» New Wiki Articles
GHB
NET

Sitelinks: Information:

All times are GMT +1. The time now is 12:10.


Copyright: SIN Foundation 2003 - 2014, All rights reserved