Combinations - Parnate (tranylcypromine) for a Methadone patient, safe? - Drugs Forum
Drugs-Forum  
News Groups Blog Forum Chat Video Audio Images Documents Wiki Home
Go Back   Drugs Forum > VARIOUS DRUGS > Various drugs not covered by other forums > Antidepressants
Register Tags Mark Forums Read

Notices

 
 
Thread Tools Display Modes
Prev Previous Post   Next Post Next
  #1  
Old 06-06-2009, 19:02
PetersKeys PetersKeys is offline
Newbie
 
Join Date: 06-06-2009
Location: USA
Posts: 3
PetersKeys is an unknown quantity at this point
Points: 78, Level: 1 Points: 78, Level: 1 Points: 78, Level: 1
Activity: 0% Activity: 0% Activity: 0%
Parnate (tranylcypromine) for a Methadone patient, safe?

I am really stuck in a problem right now. I have very bad depression and my physciatrist wants to start an MAOI on me(Parnate). However my MD tells me Parnate and methadone are a risky mix. I went on the an interaction site and I found

CONTRAINDICATED: The coadministration of narcotic analgesics and monoamine oxidase inhibitors (MAOIs) may rarely result in hypotension, respiratory depression, or coma. The mechanism is unknown but may be related to additive CNS and respiratory depressant effects. Rare case reports of severe hypotensive reactions have included propoxyphene (with multiple medications), morphine, and methadone, although others have reported the safe use of MAOIs with narcotic analgesics including methadone and morphine

So what should I exactly do in this type of position? I really want to try the Parnate because the SSRIs have not worked on me and I hear its super effective, but Im afraid of seratonin syndrome.
Reply With Quote
 

Bookmarks

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
article- negative effects of methadone?? old hippie 56 Opiate addiction 8 30-10-2008 16:32
Bioavailabilities of rectal and oral methadone in healthy subjects (2004) OhCasey Opium, Opiates & Opioids 1 21-08-2008 09:42
Methadone Rises as a Painkiller With Risks Metomni Health (News) 8 18-08-2008 19:27


Sitelinks: Site Functions:

All times are GMT +1. The time now is 21:39.


Copyright: Substance Information Network 2003 - 2009, All rights reserved