Combinations - Is there any drug that should NOT be combined with weed?

[coelho]

Well... from all swim knows, cannabis is a very harmless substance, and so it could be combined with any other substance/drug. But swim is not a doctor and he can be very wrong...
So he asks swiy, experienced users, is there any substance/drug that should NOT be combined with cannabis? And if so, what are the adverse effects/reactions?

[HorseBucket]

SWIM hears that smoking weed while on ayahuasca is intense. So intense you wouldn't wanna do it unless your prepared.

[HandFedFred]

Swims pet golfish knows that smoking weed after heavily drinking alcohol can be a very bad idea which causes white outs and vomiting. Swim reckons lots of other peoples pet fish knows about this too.

[wtfdustinwtf]

Originally Posted by HandFedFred

Swims pet golfish knows that smoking weed after heavily drinking alcohol can be a very bad idea which causes white outs and vomiting. Swim reckons lots of other peoples pet fish knows about this too.

For swim its always quite the opposite. After a heavy night of drinking swim smokes a bowl to help him wake up at what ever hour of morning is called for, to be able to take on the day with out feeling too "hung over". That being said swim feels a bit weird that weed has always helped him in those ways . When ever there was a bad next morning smokeing a little bit helped in either A, fall back asleep or B feel less like throwing up.

[Mr.Safety]

Originally Posted by HandFedFred

Swims pet golfish knows that smoking weed after heavily drinking alcohol can be a very bad idea which causes white outs and vomiting. Swim reckons lots of other peoples pet fish knows about this too.

Swim has had the same experience. Would not recomend mixing with alcohol.

[psychs]

It is fine as long as you smoke before you drink. Swim saw someone do it the other way around last weekend and end up throwing up everywhere. Weed is amazing for hangovers tho.

[Sameria]

Originally Posted by psychs

It is fine as long as you smoke before you drink. Swim saw someone do it the other way around last weekend and end up throwing up everywhere. Weed is amazing for hangovers tho.

SWIM has a fair bit of experience mixing alcohol and cannabis (it's his favourite combination) and has found that this "rule" doesn't seem to apply to him. SWIM has no trouble mixing both drugs in any order, as long as the alcohol intake is kept responsible.

One of SWIM's friends regularly enjoys a chop before a big night out drinking and swears by it.

SWIM's other friend, on the other hand, spews almost instantly if he has even a small toke after he has been drinking.

Can't argue with weed being a god-send for hangovers

[helikophis]

Some people report very unpleasant experiences from the combination of cannabis with diphenhydramine (Benadryl). The diphen seems to massively potentiate the cannabis, especially the aversive/paranoiac effects, resulting is overwhelming experiences. I haven't seen or heard any reports of people dying or being injured from it, but it doesn't sound like it feels nice at all.

[Drats]

Weed as standalone drug is mentioned harmless, yes. But a combination makes a completely different situation in the body, so a harmless drug can also lead to a lethal situation. In Denmark it´s reported that someone died of a combination from Mephedrone and Cannabis, of course mephedrone is dangerous, also they could not proof that this combination did it.
But most uppers like Amphetamine, Ephedrine etc. are raising the blood pressure, enhances the heart rate and make the veins tighter. So combined with Cannabis this can also lead to circulatory collapse.
In the end, mixing anything can make the use more dangerous. It should allways be compared how they react in the body, if two kind of drugs are combined, which make opposit effects in the body, this can allways lead to a collapse or in worst case to a stroke.

Reputation Comments on this post:

Interesting post, good info

[Nemba]

Originally Posted by Drats

But most uppers like Amphetamine, Ephedrine etc. are raising the blood pressure, enhances the heart rate and make the veins tighter. So combined with Cannabis this can also lead to circulatory collapse.
In the end, mixing anything can make the use more dangerous. It should allways be compared how they react in the body, if two kind of drugs are combined, which make opposit effects in the body, this can allways lead to a collapse or in worst case to a stroke.

SWIM is pretty sure cannabis is a pretty mild vasodilator (widens and relaxes the blood vessels). He doesn't think cannabis's opposite effect is strong enough to let anything collapse unless maybe the veins have been weakened because of hardout stimulant abuse first. Not 100% sure but the only info he could find on this suggests that stimulants can cause vein damage in extreme cases and that cannabis can often be used to help this. Something SWIM concurs with, if he hadn't had plenty of weed and a little alcohol (also a vasodilator) he doesn't know what he would have done to deal with the pain of his 25mg DOC trip (a very strong vasoconstrictor, dangerous above 15mg or so because of it).

And regarding cannabis while drunk, there are several factors.

The main reason to smoke first seems to be that once cannabis is in effect and it's anti-nausea power kicks in, it makes it relatively easy not to vomit. If swiy drinks moderately beforehand, and has a strong stomach, swiys are not likely to vomit when having a moderate session either, but being very drunk makes swiy more likely to take big tokes, and their fast and instant effect on the airways can hit the gag reflex. So if swiys are already very drunk, and take a hit, not feeling how huge it is, but the weed hasn't come up yet to protect swiy from feeling sick, welcome to nausea-town!

Swim finds when he is very drunk he can avoid feeling sick if he concentrates very hard on taking a very small toke, and then waiting till the airway/coughing/etc. effects have gone before having more.

[Sameria]

SWIM has noticed recently that even when his friends take smaller hits whilst already drunk it still upsets their stomach's, one friend inparticular.

SWIM can't seem to induce nausea with alcohol + Marijuana. SWIM had only vomited 2 times due to intoxicants in his entire life. I guess he is just blessed with a strong stomach

[Nemba]

Originally Posted by Sameria

SWIM has noticed recently that even when his friends take smaller hits whilst already drunk it still upsets their stomach's, one friend inparticular.

SWIM can't seem to induce nausea with alcohol + Marijuana. SWIM had only vomited 2 times due to intoxicants in his entire life. I guess he is just blessed with a strong stomach

Yes, when swim does this he does feel a little nausea initally, but as soon as the weed's anti-nausea power kicks in that disappears and he is then able to smoke a little more.

Originally Posted by psyche

I remember erowid listing venlafaxine as contraindication in combination with weed. It's SNRI, right? So excess noradrenaline would be the issue.

Why yes, you're right. It seems there are 2 reports of adverse effects with that combination, http://www.erowid.org/experiences/exp.php?ID=25164 and http://www.erowid.org/experiences/exp.php?ID=37376, while others report no such effects. However, they were very very bad, big cardiac and respiratory problems, so it is probably not a good idea for any swiys to ever smoke weed if they are taking effexor.

[EscapeDummy]

Originally Posted by Nemba

SWIM is pretty sure cannabis is a pretty mild vasodilator (widens and relaxes the blood vessels). He doesn't think cannabis's opposite effect is strong enough to let anything collapse unless maybe the veins have been weakened because of hardout stimulant abuse first. Not 100% sure but the only info he could find on this suggests that stimulants can cause vein damage in extreme cases and that cannabis can often be used to help this. Something SWIM concurs with, if he hadn't had plenty of weed and a little alcohol (also a vasodilator) he doesn't know what he would have done to deal with the pain of his 25mg DOC trip (a very strong vasoconstrictor, dangerous above 15mg or so because of it).

Swim would like to disagree with you. He used adderall 7-8 times, in doses ranging from 15-50mg... his heartrate skyrocketed anytime he combined it with cannabis, and would strongly urge anyone to reconsider doing that. The vasodilator vs. vasoconstriction isn't the thing that gets you, it's that amphetamines increase HR and blood pressure by a lot... and cannabis increases HR, and decreases blood pressure mildly. One is left with higher BP than normal, and a vastly higher HR, it can be very uncomfortable.

EdiT: not everyone reacts like Swim does, but he hasn't used and doesnt plan on using amphetamines any longer for his bad amphet+weed experience(s).

[Navaro]

my dog smoked weed with every drug he's ever taken and the short answer is;
NO!

Smoking pot while using MDMA or Shrooms, or even alcohol is always a must.
(Especially MDMA, he loves nothing more than to smoke 3-4 blunts while rolling hard!)

But I guess everyone is different.

Reputation Comments on this post:

	this applies to me - must try form them hangovers
	careful, this post is full of incrimination. You just admitted to using 4 different illegal chemicals.

[ThePoindexter]

Stay away from barbiturates, particularly butalbital (in the medication Fioricet). SWIM ended up in the hospital out of their mind and combative after accidentally (the MJ was ingested without SWIM's knowledge) eating marijuana brownies. As well, certain synthetic opaites can cause severe respiratory distress.

[shygon]

swim had come to conclusion that taking heroin while already intoxicated from weed, potentiates the paranoia induced by THC. Swim doesn't have an opinion for the other way around. 3-4 times in his life, he just did some nasal heroin after smoking pot and felt some highly-unpleasant dysphoria, whilst he took heroin alone some other time and felt great.

[psyche]

I remember erowid listing venlafaxine as contraindication in combination with weed. It's SNRI, right? So excess noradrenaline would be the issue.

[MasterG]

I believe that combining marijuana and alcohol at rediculous amounts of each can be dangerous becuase weed often makes people anti-vomitose (made up word for not being able to vomit as easily). As a result the body can be succoumbing to alcohol poisoning and not realize it and not be able to throw up.
SWIM however loves the combination of alcohol and weed, at moderate levels of both. This is possibly one of his favorite things. SWIM has always drinkin first before smoking and has not noticed any nausea. However he has never tried smoking before he drinks.
But anyways i believe that Jimi Hendrix died after passing out and throwing up (and choking on his vomit) backstage while drunk and high. RIP.

[psyche]

I believe that combining marijuana and alcohol at rediculous amounts of each can be dangerous becuase weed often makes people anti-vomitose (made up word for not being able to vomit as easily). As a result the body can be succoumbing to alcohol poisoning and not realize it and not be able to throw up.

SWIM disagrees. He thinks that it's much more common to get nauseated and vomit when smoking weed very drunk, rather than not being able to puke. In fact he has never heard anyone tell him this, but numerous people have told him that this combination makes puke fly easily.

[shivakiva2112]

Marijuana does not typically combine well with cocaine. YMMV, but many swimmers have reported that toking up while coked out can give you The Fear, in a bad way.

Pot definitely causes tachycardia and increased perception of bodily processes, neither of which is typically a good thing in the depths of a cocaine/stimulant binge.

[lestat737]

This rings quite true for swim as well
After a few lines, toking up would ruin the experience.

In regard to opiates, swim always found it quite pleasureable to smoke about a half hour before consuming 30mg of oxycodone. *Itch itch itch*

lestat737 added 0 Minutes and 51 Seconds later...

Oops! Swim meant after a few lines of cocain.

lestat737 added 0 Minutes and 42 Seconds later...

Cocaine**

[chilipeppers6]

For swim Amphetamines and uppers would b what he would stay away from while smoking weed. Swim already has an overly high heart rate and weed realy makes swims heart pound so swim has realy felt like he was about to faint smoking weed while popping adderall or snorting focalin. Swim enjoys marijuana much more than normal though when he combines it with something like alcohol or valium or xanax. other depressants. However swim does not like to smoke on h not because it makes him feel like hes gonna faint but h high is so good swim would prefer just h.

Reputation Comments on this post:

Good comparison and also pointing on unpleasing effects through combinations is allways a good thing