Side effects - If you have experienced side effects with Mephedrone, then read this.

[Alfa]

There are several threads that together expose that there is a real danger with mephedrone:

1. Mephedrone: body turned blue with red and purple, limbs numb. URGENT RESPONSE NEEDED!
2. Mephedrone (2-Methylamino-1-p-tolylpropan-1-one) experiences
3. Should swim be worried about extreme cold/freezing on mephedrone?
4. mephedrone is not a toy: Heart problems
5. Mephedrone hospitalization: Purple knees, extremities
6. Mephedrone: Potential Neuropathy - Extreme side effects. PLEASE READ
7. 4-Methylmethcathinone (2-Methylamino-1-p-tolylpropan-1-one) "mephedrone"
8. Mephedrone violent convulsions: hospitalisation
9. mephedrone: felt like his heart was going smash through his rib cage
10. Mephedrone fatigue: heart & breathing problems
11. Help Feeling Mephedrone effects 48+hrs after last dose
12. Teenager dies of mephedrone overdose
13. Possible mephedrone death
14. Research Chemicals (Methylone and Mephedrone) and amnesia

It has come to my attention that there are quite a few members and likely readers as well, that have experienced side effects from mephedrone, but have not posted about this. It seems that the above is only the tip of the iceberg.

If you have, then please let us know. Either by posting or if you want to add your experience anonymous, then you can send me a message by PM or the contact form.

Reputation Comments on this post:

	very good thread that gives overview of dangers!
	Good Harm reduction

[lineartransform]

SWIM's report:

Infrequent (1-2 times a week, not exceeding 3-4 times in a month) use, roughly 500mg a time. Typical dosage regimen would be 100-200 administered rectally, followed by 25-50mg bumps every 15-30 minutes for a period of about 3 to 4 hours. SWIM made an effort to keep hydrated and eat (trail mix) during, but often was distracted and forgot. Following this, SWIM would typically go for a walk, then smoke cannabis.

Negative side effects noted 4-7 days after last use:
-anger and frustration came more easily to SWIM the days after
-heart beat more "prominent", but could be psychosomatic
-more difficult to get up in the mornings
-cannabis appears to cause minor visuals in the days after, especially in the transition to sleep

Positive side effects noted:
-SWIM has lost fat and gained about 5 pounds of lean muscle mass in the last month without a change in workout regimen. SWIM is hungrier and eats more. Not entirely sure as to why this is happening. Increased testosterone due to increased dopamine levels? Very odd, but SWIM will take it.

Reputation Comments on this post:

Thanks for this report

[buzzman]

Originally Posted by lineartransform

SWIM's report:
-SWIM has lost fat and gained about 5 pounds of lean muscle mass in the last month without a change in workout regimen. SWIM is hungrier and eats more. Not entirely sure as to why this is happening. Increased testosterone due to increased dopamine levels? Very odd, but SWIM will take it.

Maybe increased testosterone anythings likely.

People are describing irrational behavior days after use, maybe there experiencing 'roid rage' like symptoms.

[Synesthesiac]

I think that if MDMA had a similar strong stimulant effect like mephedrone and people were tempted to re-dose with it as much we would be seeing very similar side effects from MDMA too. When people I know have overdone the MDMA at a rave or (god forbid) daily for a week or so, they often report quite similar side effects to many people who excessively use mephedrone.

But since MDMA is not addictive we dont. Meph is not that physically addictive I would say, but its extremely tempting to redose once the comedown starsts. Not so much at all with MDMA.

[buzzman]

Originally Posted by Synesthesiac

I think that if MDMA had a similar strong stimulant effect like mephedrone and people were tempted to re-dose with it as much we would be seeing very similar side effects from MDMA too. When people I know have overdone the MDMA at a rave or (god forbid) daily for a week or so, they often report quite similar side effects to many people who excessively use mephedrone.

But since MDMA is not addictive we dont. Meph is not that physically addictive I would say, but its extremely tempting to redose once the comedown starsts. Not so much at all with MDMA.

SWIM feels MDMA is very tempting to redose on a comedown, alot more than Mephedrone.

[freshacejay]

Originally Posted by Synesthesiac

I think that if MDMA had a similar strong stimulant effect like mephedrone and people were tempted to re-dose with it as much we would be seeing very similar side effects from MDMA too. When people I know have overdone the MDMA at a rave or (god forbid) daily for a week or so, they often report quite similar side effects to many people who excessively use mephedrone.

But since MDMA is not addictive we dont. Meph is not that physically addictive I would say, but its extremely tempting to redose once the comedown starsts. Not so much at all with MDMA.

swim has not tried mephadrone, but has a lot of experiance with redosing mdma when not supposed to... except for wasting mdma or building tolerance, swim has never had any negative side effects, definately not those stated here. when mdma wears of, swim gets tired sleeps and thats it.
swim thinks he was sold mephedrone instead of mdma recently and will, after reading reports, not take it (throwing away now).

[Joel2k11]

Well of course the worst component of this drug is how morish it is! Combine this with many negative side effects at higher doses and you don't have a good combination.

SWIM'S taken mephedrone about 7 times and he only reported negative side effects when he took 800mg in an evening. He took 200mg every 2 hours. SWIM is a 18 year old male weighing 70kg

He reports a slight feeling of dissociation, his mind felt as if it were seperate from his body for about 2 hours after the final 200mg dose. He was dosing off while browisng the internet, when he noticed that his hands and feet had turned blue. After realising this he jumped up and started to rub his feet and hands, and they quickly returned to normal colour. SWIM also reported strangely, that with such a high dose his pulse and blood pressure seemed almost normal. After this, he figured enough was enough and decided to try and sleep. Sleep was impossible for about 24 hours but during this time SWIM noted some trippy effects. He got some quite strong OEV's but strangely no CEV's. After sleep everything returned to normal.

I really would only reccomened this drug to people who feel they have a strong will to resist the urge to take more, or your health could be at risk.

Definatly would reccomened methylone over this. I find it less morish, and the euphoria lasts longer.

UPDATE:

It's been 3 weeks and SWIM tried one 200mg dose of mephedrone, and no problems were encountered. Thank God SWIM didn't pick up any long term health troubles. SWM thinks the scare helped me to be honest, no way I'm ever going to be taking more that 2 doses again!

Ahh, reading other threads now, SWIMs thrown the 6g of mephedrone he had left away, and ordered methylone instead.

Reputation Comments on this post:

Thanks for this report

[tummy_bug]

A friend of mine took about 1.5 grams nasally over the course of a week and developed a cyst on his ear about a week later. I am not sure if it was related but it was the first cyst he ever got and seemed too be a bit too much of a coincidence for him to consider researching this compound more

[hazy]

So far, SWIM hasn't experienced any side effects with mephedrone, although she has only taken it a couple of times. However, SWIM is going to a festival soon and has been unable to get hold of her usual party prescription. As this forum has put the fear of A+E into her and she'd like some advice - SWIM bought herself 2g of meph to take at the festival, and wonders what sort of dosage more experienced users would recommend as she doesn't want to turn blue and die before she gets to the DnB tent. SWIM weighs just under 10 stone and would like to be buzzed but not wasted
p.s. must apologise if this is the wrong thread, am not a frequent forum poster, just usually stumble through the internet avoiding pics of cats.

[PaulSmith10]

Originally Posted by hazy

So far, SWIM hasn't experienced any side effects with mephedrone, although she has only taken it a couple of times. However, SWIM is going to a festival soon and has been unable to get hold of her usual party prescription. As this forum has put the fear of A+E into her and she'd like some advice - SWIM bought herself 2g of meph to take at the festival, and wonders what sort of dosage more experienced users would recommend as she doesn't want to turn blue and die before she gets to the DnB tent. SWIM weighs just under 10 stone and would like to be buzzed but not wasted
p.s. must apologise if this is the wrong thread, am not a frequent forum poster, just usually stumble through the internet avoiding pics of cats.

250mg every couple of hours is fine with no more than 5 doses altogether (So don't exceed 1.25g for the day), this is how I do it and I get no side effects whatsoever.

[lineartransform]

Originally Posted by PaulSmith10

250mg every couple of hours is fine with no more than 5 doses altogether (So don't exceed 1.25g for the day), this is how I do it and I get no side effects whatsoever.

To SWIM this sounds a bit high. 1.25 g in a go is far, far higher than SWIM would recommend. I'm with you on pre-weighing out gelcaps but over a gram is excessive and in SWIM's opinion is definitely likely to cause issues - especially in a festival environment where polydrug use, proper sleep, hydratrion, and nutrition are all likely to be issues.

1.25 g in a go may not cause issues for you, but hazy should be aware that to many SWIMers, SWIMself included, 1.25 g would lead to significant tachycardia during the experience and several days of "angry blues" afterwards.

[hazy]

thanks for the info - SWIM has had to take a couple of friends to hospital whilst they were high and doesn't wish to repeat the experience.

[PaulSmith10]

Originally Posted by hazy

thanks for the info - SWIM has had to take a couple of friends to hospital whilst they were high and doesn't wish to repeat the experience.

High on mephedrone? How much did they take?

[hazy]

Originally Posted by PaulSmith10

High on mephedrone? How much did they take?

nah, one was a full scale shroom freak-out and the other was some twat at a party SWIM had who took 7 pills in a 2 hour period to show how macho he was. SWIM was not amused.

[borndizzy]

Hi, I'm new here. I just wish to say that there are different ways to make 4MMC. It depends what way the chemist uses and of course how much of the product he is willing to sacrifice in the end when washing away the impurities.
There is a wrong presumption among rc people that 4MMC has to be white color and the more white it is the better )). This is very wrong. I am working for a website who sells it and I see how it comes out of the flask -- it is beige/yellowish (and smells like hell and makes your eyes water). When it dries it gets of course lighter.
The beige color is because of the Br2 that is introduced in the 2nd stage. It is very hard to get rid of Br color. It is done with Na2SO4. BUT! This helps the formation of lacrimates. You probably know what "MACE" is, well multiply it by min 10.
The good thing about "smelly/yellowish" stuff is that its purer (if I can say so) than the really white stuff and an inexperienced chemist can really fffff up very easily because he has no control over the isomers that are forming there without good (and EXPENSIVE) analytical equipment.
Here is an example: Joe Doe and his 2 pals were doing the yellow stuff for 46 hours in a row non-stop. Dosages (through nose) were 100-150 mg every 1-1.5 hrs. After that they started doing the "parachute" way (200-300mg). Later they calculated that they had consumed ~11g of stuff. Since it was in the winter time then Joe caught cold (had to smoke outside) but other than that everybody was OK. You can easily catch cold because it is very similar to Meth and gives you a false sense of warmth.
That's all I wanted to say. Just look out who you are buying from.

!!! PEACE & UNITY !!!

Reputation Comments on this post:

Nice to have a science bit mixed in with the thread

[lineartransform]

Originally Posted by borndizzy

Hi, I'm new here. I just wish to say that there are different ways to make 4MMC. It depends what way the chemist uses and of course how much of the product he is willing to sacrifice in the end when washing away the impurities.
There is a wrong presumption among rc people that 4MMC has to be white color and the more white it is the better )). This is very wrong. I am working for a website who sells it and I see how it comes out of the flask -- it is beige/yellowish (and smells like hell and makes your eyes water). When it dries it gets of course lighter.
The beige color is because of the Br2 that is introduced in the 2nd stage. It is very hard to get rid of Br color. It is done with Na2SO4. BUT! This helps the formation of lacrimates. You probably know what "MACE" is, well multiply it by min 10.
The good thing about "smelly/yellowish" stuff is that its purer (if I can say so) than the really white stuff and an inexperienced chemist can really fffff up very easily because he has no control over the isomers that are forming there without good (and EXPENSIVE) analytical equipment.
Here is an example: Joe Doe and his 2 pals were doing the yellow stuff for 46 hours in a row non-stop. Dosages (through nose) were 100-150 mg every 1-1.5 hrs. After that they started doing the "parachute" way (200-300mg). Later they calculated that they had consumed ~11g of stuff. Since it was in the winter time then Joe caught cold (had to smoke outside) but other than that everybody was OK. You can easily catch cold because it is very similar to Meth and gives you a false sense of warmth.
That's all I wanted to say. Just look out who you are buying from.

!!! PEACE & UNITY !!!

I'm confused - if cleaning it with Na2SO4 causes formation of lacrimates, why does the "white stuff" not smell at all? I'm also a bit concerned about your nomenclature - in my experience, lacrimation is an effect of a compound, not a class of compounds itself.

It concerns me that you may be "pushing" a certain type of mephedrone that may be more profitable for you. Obviously I do not wish to directly accuse you of such, but more information would certainly clarify things.

Reputation Comments on this post:

Good that you noticed this.

[borndizzy]

English is not my first language. I looked it up and in eng. this class of chemicals (e.g. chloroacetophenone) is called 'lacrimators' not 'lacrimates'. My mistake.
I'm not trying to 'push' anything. Just thought some chemistry 101 can't hurt.

[lineartransform]

Originally Posted by borndizzy

English is not my first language. I looked it up and in eng. this class of chemicals (e.g. chloroacetophenone) is called 'lacrimators' not 'lacrimates'. My mistake.
I'm not trying to 'push' anything. Just thought some chemistry 101 can't hurt.

Fair enough, thanks for the clarification. My only remaining question would be why the "white stuff" doesn't seem to smell of anything, including lacrimators?

Is your concern with the "white stuff" not lacrimators, but isomer formation? I'm just a bit confused about what exactly the contaminants in the "white stuff" would be relative to the slightly brominated "yellow stuff".

[borndizzy]

I think what happens is some kind of isomerization. I haven't done NMR on the other 'bad' stuff so i don't know. No one will go through separating the isomeres - this will make product too expensive.
Anyway Mr. Doe is getting a batch ready tomorrow with a slight modification in technology so it should come out whiter than late Michael Jackson )).
All I know is that Mr. Doe & Associates have probably chosen the right route since no complaints of health issues have not came in for over 6 months since they are doing it. And he also does a biotest himself to every batch so ... he must be doing something right.
I think he'll have to buy some of the other stuff analyze it and compare to his.
I am not a neurochemist or MD so I really cannot speculate. I can only look at the things from the chemical point.

[bushman]

So are all negative side effects caused high doses/ redosing?
SWIM is concerned about this but doesn't want to dispose of his stuff.

Cheers dudes...

[Alfa]

The negative side effects are not due to very high doses. 100 - 200 mg is one dose, while taking multiple doses accumulating 500 mgs over 12 hours can cause these side effects.

[Space Numpty]

Hi there i wondered if anybody could give me some advice.

The other day my model tank decided to try meph. He is quite a big tank and he ingested 1 gram over 12 hours both orally and insufflated. He noticed it was more "twitchy" than MDMA, it made him a little paranoid, but overall it was ok.

The problem is that it has been 5 days since my tank indulged and he is still feeling very odd. High heart rate, anxiety, disassociation, light headedness, tingling in his face and hands, he doesnt feel well atall and is struggling to function.

One thing is my tank is on a carb free diet. Could this be having a negative effect? He noticed in the forums mention that a carb rich diet could help with a Meph "hangover" and wonders if a carb free diet could be causing him his woes?

[thv20]

Originally Posted by Space Numpty

he ingested 1 gram over 12 hours

SWIY has probably gathered by now that that is approximately 4 to 5 times more than the current "recommended" dose. In doing so, negative effects are significantly exacerbated.

Originally Posted by Space Numpty

One thing is my tank is on a carb free diet. Could this be having a negative effect? He noticed in the forums mention that a carb rich diet could help with a Meph "hangover" and wonders if a carb free diet could be causing him his woes?

It could be a contributing factor, however... rather than eating some pasta I would urge SWIY to seek medical advice as the symptoms are persisting. In the mean time, it may not be a bad idea to avoid other stimulants such as caffeine.

Hope SWIY feels better soon

[Space Numpty]

SWIM's tank went to the docs today. He wasnt surprised that his doc hadn't even heard of meph and could offer little advice. SWIM's tank was pleased to note however that his pulse and heart rate where normal, and he has been given a short course of Propranolol to chill him out.

SWIM's Tank feels that the worst is behind him but he wishes to warn other SWIMmers of these effects. SWIM's Tank has been a very heavy user of more common "street" versions in the past and has never suffered the prolonged effects he has with Meph. Perhaps it has something to do with him being on a carb free diet and therefore in "Ketosis", SWIM's Tank isnt sure, but one thing he is sure of is that just because it is legal, that doesnt make it safe. SWIM's Tank feels that if a bigger Tank made him take something by force he would much rather go for a "street" version that at the very least we know something about, taking Meph is a very definate gamble. Other than that SWIM's Tank will be sticking to the gifts God gave us.

Reputation Comments on this post:

Thanks for the update.

[Alfa]

Unable to function 6 days after Mephedrone incident