Drug info - One Methadone Myth

[tyranny4u]

Methadone was never synthesized by the Hoechst chemists because
of an instruction of "the nazis". It also was not part of the standard
equipment of the soldiers, as even some Physicians tell their patients
still these days.

Methadone was found after a series of experiments that started in the
1920ies, when germany was a democratic country with a capital where
people enjoyed dancing charleston and sniffing cocaine.

The chemists at Hoechst were searching for substances for pain treat-
ment, and synthesized "Aminophenazone" and "Methamizole", the 2nd
still used today, known as "Novalgin" and several generics. Methami-
zole was found in 1921.

On their search for (stronger) analgesics with anticonvulsant effects
they then found "Pethidine", also still in use today and known as
"Dolantin, Demerol, and many more branded generics. Pethidine is an
Opioide with anticonvulsant effects, and was the substance that "the
nazis" were after, of course. Pethidine was synthesized in 1937. It was
tested for it's pharmaceutical characteristics in 1939, but put on the
market in the same year(!)

It was also 1939, the year when Methadone was synthesized for the
first time, after the chemists were running a series of experiments
with "basic substituted diphenyle derivatives" (i hope i translated right)
On this experiments Methadone was found and got registered at
Hoechst using the number "Va 10820". The analysis of the pharmaco-
logical properties of "Va 10820" were done for the first time in 1942.
Small amounts were given to the leaders of the "Wehrmacht"
(german nazi army),but there is no evidence, that Methadone was
widely-used in Germanyduring WWII. Not in the Army and not
on the civil people.
It was Pethidine, that besides of Morphine was used
in the mobile army surgical hospitals. And during the last year of the
war, only the high ranked soldiers got Morphine or Pethidine when
an arm or a leg had to be amputaded. My grandfather didn't tell a lot
about his life in the army, but he told me once about amputations
that werde done with giving the patient some vodka (or simply nothing)
while his leg got cut off with a bone saw. There was not enough
Morphine, Opium or Pethidine for those poor pigs. (yes, you call
them nazis. but my grandpa was not a nazi. he wasn't asked if
he would like to fight and kill, aged 17 he was given a gun and
that's it)

It is said that Methadone was dosaged to high in the first tests on hu-
mans, and too much negative side effects were shown, so they kept
on concentrating on the Pethidine production.

The end of the story: The Methadone patent got part of the spoils of
war that the US American army took home from Germany, a few years
later Methadone was put onto the market in both countries.


To come to an end:

Of course the nazi regime put a lot of pressure on the pharmaceutical
industry in germany during 1933 - 1945. But still today it is nearly
impossible to create a drug on demand. So you could imagine that
70 years ago expedient drugs were found accidentally, and though all the
improvements in drug finding and drug designing, accident still plays
a role in drug finding today!
The story of finding Methadone is a story that begun in 1884, when at
Hoechst "Antipyrin" was synthesized, "Pyramidon" followed 1897, then
Metamizole followed 1921, and in the twenties they started to syn-
thesize the first methadone-like substances.

BTW: to those of you who understand german or if german is your
native language, i could give you the link to the .pdf written by
Ralf Gerlach, also a list of sources used he used to write the article
is available. (Ralf Gerlach is one of the german luminaries of the
specific field "opiate addiction, treatment, politics concerning add-
icted humans, drug history...)

[Benway]

fascinating stuff

[Solinari]

A drug squad police officer told my fiend that methadone was made to kill Jews during the holocaust and that it rots your bones. My fiend didn't argue with him and just appeared surprised at what he said.

People say it stays in your bones i don't think that is true but it does get stored in fatty tissues and can stay there for quite some time because of the huge half life, to get the facts on methadone read the Methadone Handbook.