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  #1  
Old 02-05-2009, 18:24
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Anal use of Pregabalin

I'm not really expecting any responses here, as the topic is very obscure, but this is something that SWIM is interested in. SWIM has been experimenting with pregabalin recently, and in the experiences thread there was a report claiming that pregabalin administered anally came on much quicker, gave a different high, and made smaller doses much stronger.

Does anyone have any information or experiences here at all? SWIM would be particularly interested in knowing equivalent dosages between oral and anal use.
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Old 05-05-2009, 23:00
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Re: Anal use of Pregabalin

SWIM (a 75kg male) decided to gather the information himself by self experimentation; his first time administering a drug anally. He put the contents of a 75mg pregabalin capsule into water, and it didn't dissolve (which seems odd that pregabalin should be freely water soluble, but maybe more water would have been needed to dissolve all powder), but SWIM plugged the mixture. His experience agreed with that in the experiences thread. Effects were felt after 5 minutes, were very close to the peak at 10 minutes, and did peak at 15 minutes. The effects seemed a bit more relaxing than usual, and it is hard to judge but SWIM would say that it shared a duration with oral administration and this dosage is equivalent to 150-300mg taken orally. Higher doses would be needed to assess whether this is worthwhile.

Current research is showing that pregabalin reduces bowel sensitivity, so perhaps this could be less unpleasant than using other drugs anally.

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  Thanks for sharing. This great information to those who plug.
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Old 07-06-2009, 23:47
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Re: Anal use of Pregabalin

SWIM doesnt like to plug drugs, but jsut wondering when you mentioned if it is water solublew or not? cause SWIM wants to know if it is worth snorting it?
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Old 08-06-2009, 10:26
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Re: Anal use of Pregabalin

Swims used the drug rectally and notices the drug is about twice as potent rectally as orally. Swim also notices that its alot more soluble when the cap is opened first and the powder emptied out but if you dont want to go through the hassle hot water will easily dissolve the whole capsules. Just let it cool down a little before plugging.
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