Anal use - Rectal Administration of Phenethylamine/Tryptamine Research Chemicals

[Shampoo]

The dosing of phenethylamine and tryptamine research chemicals via rectal administration (in liquid, gel-cap, or otherwise) has been discussed briefly in some threads and on other forums, and the results seem to be relatively consistent: reduction in nausea, drastically reduced "come-up" time, slightly decreased duration of action, and perhaps most importantly, increased bioavailability (resulting in the reduction in necessary dose).

I have been unable to find, however, any significant amount of user reports or experience reports of RC administration via this method. I think it would be very helpful to amass some general experiences with rectal RC administration to create "normal" or "accepted" values for variation/changes in the following (as compared to other routes of admin):
*Dose
*Duration
*Latency in "come-up"
*Main-effects
*Side-effects

Please post here experiences with rectal dosing of any tryptamine or phenethylamine research chemicals. Be sure to include the name of the RC, the method by which rectal admin was applied, the dose taken, and all of the other above qualities. All additional information is welcome. Reports in this thread with good detail and organization will be highly appreciated and rewarded with significant reputation (and respect).

Reputation Comments on this post:

Very good idea for a thread, will be interesting to see what people report.

[Shampoo]

Alright then, shall we start things off with some posts from around the forum?

2C-C:

I have tried administering 20mg of 2C-C rectally; I'd not do it again in a hurry. It came on really quickly, but that wasn't the problem, it was that it wasn't the laid back experience that say 35mg adminsterd orally would be. In fact it didn't feel much like 2C-C at all as the mental effects were things like thoughts coming too rapidly and it was forced on you. I've never had a challenging/bad experience with phenethylamines, but that was the closest I've ever come to one and with 2C-C of all things

*written prior to the application of self-incrimination protocol*

2C-D:

2CD feels like a very safe material...SWIM would have no problem pushing that chemical up to 100mg oral (or more). SWIM has tried 32mg rectal and that was the best 2C experience he ever had (he's tried 2CB, 2CD, and 2CE). By far the best visuals, best body high, deep cognitive content. Really a lot like 2CB except much deeper cognitively and more rich visually (much like 2CE except without the intense 'mindfuck' SWIM gets on that chem).

There are reports of people pushing this chem up into the mid 100s orally, and as high as 75mg rectal.

2C-B:

As far as this gnome has been told the burn from plugging is nowhere near as bad.

[comparing to intranasal administration]

2C-T-4:

So, anyway, he shot this shit up his ass--mixed with 1/2 a bar of xanax (1mg) dissolved as well. It took about 5cc's to shoot that and about 10mg 2c-t-4 into his asshole.

WELL---forget everything I said about needing 50mg to get off. He got off and HARD! It was loads of fun though, as he reported to me. VERY visual, characteristic 3D overlays to everything, and extrememly pleasant mood.

2C-T-7:

A fantastic summary-post has been made here: http://www.drugs-forum.com/forum/sho...61&postcount=9

BrDFLY:

I took about 150mics rectally three hours ago. I can't be sure, but it seems to be active by this route. I'm experiencing a slight, but agreeable, shift in general feeling-tone and - I think - some colored CEVs. I suspect that this trip may develop furthur, in which case I'll report back.

*written prior to the application of self-incrimination protocol*

5-MeO-DiPT:

7mg 5-meo-DIPT (rectal) plus MDMA (oral) = sex heaven

NOTE: Some of these posts contain concomitant administration of other chemicals, making them next-to useless in determining the efficacy of rectal admin. The are still posted here nonetheless as a general sign that a.) they can be taken rectally and b.) the general dose increase/decrease associated with rectal admin.

[fnord]

and perhaps most importantly, increased bioavailability (resulting in the reduction in necessary dose).

Not counting less nasuea will a reduction in dose mean a reduction in potentil side effects? Or dose the increased bioavilibilty also increase side effects as well?

[Shampoo]

Originally Posted by fnord

Not counting less nasuea will a reduction in dose mean a reduction in potentil side effects? Or dose the increased bioavilibilty also increase side effects as well?

Perhaps, though this has not been confirmed as far as my knowledge is concerned.

Theoretically, many of the side effects which arise from oral RC administration occur due to the compounds binding with 5-HT receptors outside of the brain. 5-HT receptors are distributed throughout the body. For instance, 5-HT receptors are present in the human digestive system, most likely accounting for nausea/stomach cramping (the result of the tryp/phen binding to and "activating" 5-HT receptors in the gut). So theoretically, binding of RCs to peripheral tissues which contain 5-HT receptors may decrease as the route becomes more direct to the bloodstream (though to be perfectly honest, I have no idea what route blood from the anus takes before entering the brain).

Have any lab-rats out there experienced a reduction in general side-effects from rectal dosing?

[Synesthesiac]

Swim has done 2C-I rectally, snorted and orally so can compare the methods quite well. Swim found that with 15mg swallowed orally it took an hour for any effects to be noticed, two hours for main effects to start, and probably the peak was at three hours, with after effects lasting 6-8 hours. Very large body buzz, swim could not help stretching out his arms and legs all the time because this felt great and he was tingling all over. The visuals were there, you could tell the world looked 'different' in the usual way, but not really many noticeable things that you could point out to as fully 'tripping' as such. Everything was just a bit 'wavy'. Swim was also very hot/cold the whole time throughout this, and had to keep taking his jumper off/on where his temparature kept bouncing up and down. Quite a high body load, but countered with nice bodily effects at the same time.

With 10mg 2c-I taken rectally swim said effects were felt after about 10-15 minutes. There a nice smooth transition from sober to under the influence, not as fast as one might imagine insufflating the substance, but not gradual as orally. Devoid of that sometimes unpleasant 'just coming up' feeling. After about 30-45 minutes all the main effects were there, and it was a much more visual experience, without the body buzz of his previous experience. His skin felt warm and nice to touch, but nothing like last time where his whole body was writing in sensory overload. Peak was at about an hour, and after effects about 3-4 hours. He had mild hand trails when he moved his hands, and colors and patterns were all merging and writhing as if alive. Just staring at his colored blinds was like watching a movie unfold infront of his eyes. This one felt much stronger than his first, despite the reduced dosage, but its hard to compare really as it felt like a completely different experience all together. No body load at all.

Also, swim has also snorted 5mg of 2c-I and got no effects at all. He was going to snort another 5mg of 2c-I to see if this gave any appreciable effects, but he was still running round the room in circles clenching his nose screaming "ouch ouch ouch" from the burning of the last one. Swim highly advises not snorting any 2c's, says its like sniffing chilli powder.

Swim has also plugged 8mg of 2c-b-fly (he infact did it in conjuction with 5mg 2c-I rectally, so its hard to separate the effects of each) which gave a very visual experience, that lasted about four hours. Though its hard to tell which substance was the main active one in this case.


Swim is currently on an SSRI for another 3 months, so his stash of 2c-X's is gonna have to wait. But give it a couple of months and swim should be able to add the difference between oral and rectal admin of 2c-B, 2c-E, 2c-t-7 and 2c-b-fly. Overall swim thinks its a much better method of administration than other methods.

Reputation Comments on this post:

great comparison

[Synesthesiac]

Swims had a go with 2c-d the last few days. Report as follows.

• body weight & sex: Male, 68kg
• dose taken: 30mg
• route of administration: Rectal administration
• Setting: In swims room by self
• duration of main effects: 2 hours
• main effects: Visual. Hand trails, Color enhancement, Blurry wiggly lines
• side effects: None notable
• after effects: None notable
• rating of the experience:7/10
• addictive qualities / abuse potential: None
• any other valuable information: Taken with 3 grams of diluted GHB, and while on an SSRI, 20mg daily of Citalopram.

Rectally:

t=0 30mg plugged in gel cap

t+40 Effects started to show. Colors started to appear more vivid and things seemed more vibrant.

t+60 Peak reached. Nice effects, very subtle compared to most other 2c-x compounds, but the mindset is very much the same.

t+100 Effects starting to subside. Definate hand trails and visuals still there however.

t+ 120 Pretty much back to normal.

Insufflated:

t=0 20mg snorted. Ouch! Very, very, very painful to snort.

t+5 Effects nearly instant, instantly had color enhancement and trail effects. Music was greatly enhanced.

t+10 Peak reached, seemingly much stronger than the previous rectal experience. Effects are very prominent, about 1.5 times as intense as the previous experience

t+30 Effects startinhg to subside.

t+40 Nearly back to normal.

Rectally was much better in swims humble opinion, snorting was too painful and didn't last long enough.

Reputation Comments on this post:

Great information to know. Than you so much for sharing this since there is very little information on rectal administr...

[RaverHippie]

I will get in touch with my raver friend at the party I'm going to tonight and convince him to enlist into such an endeavour. He may have tools to execute a trial for 2C-T-2 and can conduct it against a very lengthy history with the drug so the contrast will be vivid and obvious.

[slownerveaction]

A note on rectal administration of 2C-E can be found in the 2C-E experience thread: http://www.drugs-forum.com/forum/sho...637#post640637

[researchbishop]

SWIM will soon be doing some research in the "poop-chute" method of administration, they will report when complete. However perhaps someone can tell SWIM whether this will work well enough.....

Obviously the syringe method is best and if at home that is what SWIM will do, however for "in the field" research not quite so convenient, SWIM is planning on attending a music festival soon, and for this "in the filed" research and was going to have the chemicals preprepared out as appropriate, wrap them in a cigarette paper (rizla) and blam straight up there, where the sun don't shine, maybe whilst in the toilets mind you.

SWIM has never heard anyone using this exact method before, anyone think of any issues with it, apart from the obvious unpleasantness, which SWIM is prepared to suffer, in the name of research.