Dose - Abusing Vyvanse

[XombieShovel]

SWIM raves alot. SWIM has found that abusing Vyvanse at a rave, although not as fun, is almost as fun as taking MDMA and rolling, but Vyvanse is safer and cheaper too.

SWIM is prescribed 50mg capsules of Vyvanse, and has abused it up to 100mg with ENORMOUS amounts of caffeine and energy drinks before. SWIM would like to start going beyond 100mg.

Does anyone have any advice for SWIM? What can SWIM do to maximize the effects of Vyvanse? At what dosage does Vyvanse start to really get dangerous? Is there a "golden" dosage of Vyvanse? What should SWIM not do or take while abusing Vyvanse?

[cra$h]

keep the fluids up. it's an amphetamine, so just do as you would regularly. If you're pushing some crazy high doses, then meth might be the better option. but 100mg isn't all that bad. watch your heart too. take a break and cool off if it's going faster than the music!

[XombieShovel]

Thx, SWIM wanted to start low and work his way up. SWIM may one day go as high as 300mg, but will play it safe for now.

[Capita]

Swim thinks takeing more vyvanse will only make it last longer and make you feel carpper because vyvanse is a prodrug and is broken down by a enzyme. So it can only break down the non active amp into active amp as fast as the enzymes work. This means theres a limit on how high swiy can get from vyvanse.

[Boca Bitch]

Originally Posted by XombieShovel

SWIM raves alot. SWIM has found that abusing Vyvanse at a rave, although not as fun, is almost as fun as taking MDMA and rolling, but Vyvanse is safer and cheaper too.

SWIM is prescribed 50mg capsules of Vyvanse, and has abused it up to 100mg with ENORMOUS amounts of caffeine and energy drinks before. SWIM would like to start going beyond 100mg.

Does anyone have any advice for SWIM? What can SWIM do to maximize the effects of Vyvanse? At what dosage does Vyvanse start to really get dangerous? Is there a "golden" dosage of Vyvanse? What should SWIM not do or take while abusing Vyvanse?

Vyvanse is not in any way safer than MDMA. Doperminergic stimulants are notoriously damaging physiologically and psychologically; while comparatively, the serotonergic empathogens tend to be a lot more benign. However, since it's doubtful that SWIY has found pure MDMA, Vyvanse (which is FDA regulated) would be more predictable in effect.

The combination of amphetamines and caffeine should be avoided. Caffeine has a powerful potentiating effect on amphetamines, that can result in excitotoxicity (neural death due to overstimulation) at a much lower of a dose than amp alone. And if SWIY should decide to consume caffeine, at least choose a source that's lower in sugar. Energy drinks are just about the worst hell you can put your body through while amped. Amphetamine causes a significant release of both norepinephrine and epinephrine; these excitatory neurotransmitters are responsible for triggering the "flight or fight" response when released. As part of preparing one's body for action, blood-sugar levels sharply increase. Combining the already highly elevated glucose levels with more refined sugar can cause severe damage to insulin production, potentially triggering the on-set of diabetes in those pre-disposed.

The exact lethal doseage of amphetamines is not entirely understood nor properly tested.. it can greatly vary from one individual to another. Generally speaking, upwards of 500mgs. is more likely to result in fatal od, while upwards of 150mgs. is likely to result in non-leathal overdose. But there are many variables that can alter what would normally be a safe dose, such as tolerance and stomach acidity (if taken orally).

[Potter]

Boca Bitch: Actually you're figures are rather low.

(from PDR 1998's amphetamine prescription information)

Individual patient response to amphetamines varies widely. While toxic symptoms occasionally occur as an idiosyncracy at dosages as low as 2mg, they are rare with doses of less than 15mg; 30mg can produce severe reactions, yet doses of 400 to 500mg are not necessarily fatal. In rats, the oral LD50 of dextroamphetamine sulfate is 96.8 mg/kg.

from the MSDS sheet

ORL-HMN TDLO 41 mg kg-1
ORL-RAT LD50 55 mg kg-1
IPR-RAT LD50 125 mg kg-1
ORL-MUS LD50 24 mg kg-1
IVN-MUS LD50 68 mg kg-1
ORL-DOG LD50 23 mg kg-1

Dr. Rodger C. Smith found cases of people mainlining 15,000 mg of speed, that's 15 grams of the stuff, these were isolated cases and in no way representative of sane doses. He does state that most people can withstand direct injections of 400-500 mg, even if they never took the drug before.

Not that taking more then 60mg doesn't produce some level of discomfort in most folks. Nobody has to say "working up to 300mg" sounds like a fantastic way to become an addict. Frankly they'd place good money you won't be able to quit after you do that. That sort of tolerance takes habitual addiction. You ever meet a speed addict? They get obnoxious. That stuff will change your personality, it will change your relationships, and it will change your chemistry. You should consider going and reading up in the addictions forums to get an idea of what you are getting your self into. Scientists need to fund their experiments, you've your hands on some fancy grant? What happens if the supply of the chemical dries up? Can you deal with the withdrawal when the time comes?

Experiments such as this have their uses, but one always needs to question their motives and compare them to the risks. You must take account external factors such as money, relationships, living situation. Failure to do so may lead to abject poverty or even an untimely demise.

What kind of shape is your heart in? Nobody's done some pretty massive caffeine doses and knows how that feels, mixing with large amounts of amphetamines may push your heart to it's limit. Such a reaction is likely to be fatal, the cost of bringing you back to life can be incredible, ten's of thousands of dollars. It might behoove the scientist to attempt to find an EKG of some sort and learn how to read it.

Well best of luck.