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Originally Posted by tron102
SWIM has tried several different blotters, all of which appear to be from the same source, due to similarities in the design. SWIM has experienced a +++ trip from three hits on one day, then a few months later, 3 hits may result in a mild +/++ trip.
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Were these tabs acquired at the same time? If so, how were they stored? Phenethylamine compounds tend to be extremely stable and would likely not show degradation. Tryptamine compounds such as LSD however are significantly less stable and could easily be degraded in poor storage conditions.
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SWIM has not eliminated the possibility of a phenethylamine substance on the blotter opposed to LSD. From PiHKAL, DON seems to be the most likely candidate. There isn't a particularly noticeable taste from the blotter, but SWIM does notice a very amphetamine-like feeling during the come up.
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LSD can provide some users with an amphetamine-like stimulation during the come-up period, especially if mixed with an exciting set/setting. Furthermore, and far more importantly, it is highly unlikely that the blotter your friend has acquired contains DON. First of all, DON is a very uncommon phenethylamine in terms of "street" availability. Even a well connected, thoroughly versed psychonaut like my lab-rat/test-subject has had trouble tracking that one down.
Additionally, it would be almost impossible to fit an active dose of DON on a blotter. With the dosage range of 3.0-4.5mg, at least 3 blotters would have to be consumed for an active psychedelic dose, unless of course it were thick, cardboard like paper that is not actually blotter paper. A +++ trip from 3 tabs, even assuming a high carrying capacity of ~1mg per tab, is highly unlikely from DON as doses in that range tend to produce threshold stimulation and no
significant psychedelic effects.
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am I correct in assuming that there would be no cross tolerence between phenethylamines and tryptamines?
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No, you are not correct in this assumption. The primary phenethylamines and tryptamines all act through a similar mechanism: agonization of the 5-HT-2A/C receptors. Their activity results in the downregulation of these receptors, which is the underlying neurological/physiological cause of "tolerance". Since they act through the same mechanism, there is a direct and obvious cross-tolerance between psychedelics of the tryptamine and phenethylamine families. This includes all 2C-x/2C-T-x molecules, DOx substituted amphetamines, LSD, 4-substituted-Tryptamines, 5-substituted-tryptamines, and more.
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If not, could SWIM ingest his sold-as-LSD blotter on day x, then the following day, either eat mushrooms/4-Aco-DMT. If he trips on both, and has no observed tolerence, would this conclude that the blotter contains a phenethylamine such as DON?
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No, because cross-tolerance will occur whether it is LSD or DON. Additionally, if SWIY is not familiar with 4-AcO-DMT dosing (which is very sensitive and relatively tricky) then the quantitative magnitude of the trip may be nearly impossible to qualify for comparison.
My suggestion is to get an LSD testing kit or make your own reagent or solution for testing. There is no sure-fire way to determine the contents of your blotter without GC/MS testing, but here are a few other ways (which can be found using the search engine)
1. LSD in solution (EtOH or H2O) will glow blue under blacklight exposure.
2. Exposing LSD to Ehrlich's reagent (para-(dimethylamino-benzaldehyde) in EtOH/HCl will result in a purple appearance.
3. Exposing LSD to Marquis reagent will result in an orange/brown appearance. Unfortunately, this is similar to the reaction for amphetamines, so it may be less effective in determining the presence of LSD v. a substituted-amphetamine
For more information on reagents and testing, use the forum search engine.
07-03-2009, 01:02
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