The impact of cigarette smoking on stimulant addiction (2009)

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American Journal of Drug and Alcohol Abuse 2009;35(1):12-7

Weinberger AH, Sofuoglu M

OBJECTIVES: Stimulant users smoke cigarettes at high rates; however, little is known about the relationship between tobacco and stimulants.

METHODS: Our goal in this article is to synthesize a growing literature on the role of cigarette smoking in stimulant addiction.

RESULTS: Early nicotine exposure may influence the development of stimulant addiction. Preclinical and clinical studies suggest a facilitatory role of nicotinic agonists for stimulant addiction. Smoking appears to be associated with more severe stimulant use and poorer treatment outcomes.

CONCLUSIONS: It is important to assess smoking and smoking-related variables within stimulant research studies to more fully understand the comorbidity. Integrating smoking cessation into stimulant treatment may improve nicotine and stimulant treatment outcomes.

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