Mephedrone: Potential Neuropathy - Extreme side effects. PLEASE READ
Yes, I am fully aware there is a separate page for mephedrone experiences by SWIMmers. However, since my imaginary talking rabbit has experienced a potential toxic effect from mephedrone, I thought it best to make a new post so it could be read by any seeking information on this.
It's too soon to tell if this is permanent, or merely a really, really fucking scary transient effect, but my rabbit has lost the ability to raise his left foot (dorsiflexion, if anyone here has anatomy/medical knowledge). He can raise himself on the balls of his left foot, which is plantarflexion, the opposite motion for feet, but he cannot pull his foot up towards his body.
The top of his foot is numb-ish, as is part of his ankle/lower leg. He can't tell if it's gotten any less so with time. SWIM does not know if it is against forum policy to report the duration of time that has elapsed between the last dose of mephedrone and the present, so he will not. It hasn't been long, that's all he'll say.
If anyone has had similar experiences and they turned out to be transient, please tell my rabbit, because it will ease his mind considerably. His walking gait is, for the most part, almost unaffected, though he has to put a little more thought into where he's putting his left foot. Driving (even a stick shift) is no problem, and he will experiment with riding a bike in the future. However, he tried running, and nearly broke his ankle. He is not looking forward to the prospect of being permanently, albeit mildly, disabled, especially from something as stupid as drug use.
The Wikipedia article for mephedrone lists "occasional reports of body numbness and lack of tactile sensitivity for very large amounts". My rabbit doesn't know if approximately 660 mg of mephedrone, in 100-150 mg doses, over the course of about 10 hours, is a "very large amount", or if "body numbness and lack of tactile sensitivity" is really that accurate a description for his horrifying new development, but he's hoping, because the article seems to suggest that such things are temporary.
Apparently I can't link directly to sites yet but my rabbit tells me his symptoms are very much like foot drop, if you feel like looking that up.
If this is a totally new phenomenon (hooray for SWIM ), let it be known that this compound may have serious potential for peripheral neuropathy.
There is one hope with the latter, it seems. We're probably all aware that our good friend ethanol is known for peripheral neuropathy. Apparently, at least as far as SWIM can tell, ethanol-induced neuropathy can improve, with time, once ethanol consumption is eliminated. Since my rabbit is never, ever going near this terrible chemical (or anything else, for that matter...) ever again, maybe it will improve, in time. (Sure.)
My rabbit did redose a number of times. As has been said before, the draw to do so is ridiculously strong, perhaps more so than anything my rabbit has tried before. He wrote an experience report he hates himself for writing due to it being positive towards mephedrone; this report need not be shared.
However, it is interesting to note that the numbness was noted in the report at the ten-hour mark, suggesting that any potential neuropathy induced by this compound may be due to metabolites, not the compound itself.
Any information would be welcomed. Please be careful with this awful substance. The only positive to be found from this nightmarish experience is that my rabbit has finally realized, although perhaps too late, that no transient state of consciousness-expansion or euphoria is worth risking one's ability to do really simple things like walking or running.
Hopefully, no one reading this has ever or will ever have to deal with the knowledge that you might not be able to move freely, as you have always done, and which you have always taken for granted, ever again.
Oh, and my rabbit is quite impoverished, and his medical insurance is utter shit, so he won't be able to visit a doctor for quite a while, in case anyone asks.
06-02-2009, 12:15
), let it be known that this compound may have serious potential for peripheral neuropathy. 
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