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  #1  
Old 24-01-2008, 00:02
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Re: The Combined Lunesta (Eszopiclone) Experience Thread

The 7.5mg pills you are referring to are probably Zopiclone not Lunesta, there is a slight difference, mainly due to some inactive ingredients, but it changes the dosing quite substantially.
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Old 24-01-2008, 04:38
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Re: The Combined Lunesta (Eszopiclone) Experience Thread

Yes that is correct.. do you have further detail on the difference of ingredients/dosage?.

SWIM had assumed since Zopliclone was the primary active imgrediant there would be little to no difference
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Old 24-01-2008, 09:40
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Re: The Combined Lunesta (Eszopiclone) Experience Thread

I think 3mg Lunesta equals 7.5mg Zopiclone. I'm not sure exactly of their differences but it seems that if the doses are as stated above, they have the exact same effect..... From what I have read there have been no differences in the effects anyway, if someone else has more info on this please clarify.
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Old 24-01-2008, 16:47
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Re: The Combined Lunesta (Eszopiclone) Experience Thread

SWIMS doctor prescribed 7.5mg 1 hour before bed.

From what i understand,
Brand name : lunesta has no other significant ingredients other than Eszopiclone
Brand name : Zopliclone has no other significant ingredients other than Eszopiclone

The dosage difference is most likely due to different national standards which we see with so many other drugs
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Old 24-01-2008, 19:05
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Re: The Combined Lunesta (Eszopiclone) Experience Thread

Quote:
Originally Posted by Ryu View Post
SWIMS doctor prescribed 7.5mg 1 hour before bed.

From what i understand,
Brand name : lunesta has no other significant ingredients other than Eszopiclone
Brand name : Zopliclone has no other significant ingredients other than Eszopiclone

The dosage difference is most likely due to different national standards which we see with so many other drugs
Eszopiclone is actually the potent (there are two) stereoisomer of zopiclone. Many drugs are distributed as the racemate (same compound but made of 50%:50% mix of the two stereoisomers) usually due to the ease of synthesis. Often though one of the stereoisomers will either have no effect (e.g ibuprofen), sometimes reduce the effect of the potent one or may even produce only the side effects. Pharmaceutical companies on many occasions have marketed the single isomer product to extent patent protection.

Zopiclone (Brand name = Zimovane/Imovane + more)
Comprised of both isomers: eszopiclone (the potent one) + the less potent one

Eszopiclone (Brand name = Lunesta)
eszopiclone = ONE pure stereoisomer (the potent one)

which is why eszopiclone is the stronger(more potent, lower dose) one.

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Last edited by Zaprenz; 24-01-2008 at 19:35.
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Old 24-01-2008, 19:41
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Re: The Combined Lunesta (Eszopiclone) Experience Thread

Quote:
Originally Posted by Zaprenz View Post
Eszopiclone is actually the potent (there are two) stereoisomer of zopiclone. Many drugs are distributed as the racemate (same compound but made of 50%:50% mix of the two stereoisomers) usually due to the ease of synthesis. Often though one of the stereoisomers will either have no effect (e.g ibuprofen), sometimes reduce the effect of the potent one or may even produce only the side effects. Pharmaceutical companies on many occasions have marketed the single isomer product to extent patent protection.

Zopiclone (Brand name = Zimovane/Imovane + more)
Comprised of both isomers: eszopiclone (the potent one) + the less potent one

Eszopiclone (Brand name = Lunesta)
eszopiclone = ONE pure stereoisomer (the potent one)

which is why eszopiclone is the stronger(more potent, lower dose) one.
Thanks Zaprenz very informative post
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Old 24-01-2008, 16:52
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Re: The Combined Lunesta (Eszopiclone) Experience Thread

Correction. SWIMS brand name is Zimovane
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Old 04-02-2008, 19:01
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Re: The Combined Lunesta (Eszopiclone) Experience Thread

One thing swim has noticed about Lunesta(Eszopiclone)is how fast acting they are.Swim has found that it is actually a rather enjoyable little pill.Swim thinks Ambien(Zolpiderm)is abit more enjoyable though.Ambien(Zolpiderm)has some hallucinatory effects though which is probably what makes it the more enjoyable of the Z drugs.
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Old 04-02-2008, 22:42
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Re: The Combined Lunesta (Eszopiclone) Experience Thread

SWIM finds Zopiclone to be MUCH better than Ambien, lots of of euphoria . Word of caution though, he told me that he found it much much more addictive than benzos. He took them for only 4 days in a row and then felt extreame WDs after
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Old 22-03-2008, 05:04
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Re: The Combined Lunesta (Eszopiclone) Experience Thread

ya lunesta only is prescribed in 1 2 or 3 mg i was just prescribed some today so we will see how it works tonight been sleeping like shit tired of waking up in the middle of the night
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Old 17-04-2008, 19:36
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Re: The Combined Lunesta (Eszopiclone) Experience Thread

I've tried lunesta and all the rest of the non narcotic sleep aides, it did nothing for me. I still stayed up with 10mg in me all night long the same as ambien, 10mg or more of that and was awake all night long, sometimes I go for 2 weeks on about 15 minute nap once a day, and still the non narcotic stuff doesn't work for me and doesn't produce any effects that i've noticed. I've got boxes (literally) of ambien and lunesta sitting around over here that my doctor gave me (he always gives me tons of samples if it's something he's got from the pharm company), anyway, didn't do anything for me to sleep or otherwise.

kuplo added 4 Minutes and 29 Seconds later...

SSOorry I don't see an edit button but only wanted to say one other thing, lunesta leaves the nastiest metalic taste in the mouth, can last a few minutes to many many hours. Anything you try to eat or drink will also take on that nasty metalic taste. It's rather like when you've been to the dentist and get a silver filling and get tht nasty taste in your mouth. That's lunesta. Ambiens dont leave that after taste, though for me they do nothing. Right now we're trying dalmane though they don't work worth a jive either. 90MG OF them last night and I was still up all night at the computer, still am. Waiting for the pharmacy to open to see about some soma, that used to work to put me to sleep at a high enough dosage like 2100mg (no that's not a typo).

Last edited by kuplo; 17-04-2008 at 19:36. Reason: Automerged Doublepost
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Old 17-04-2008, 20:34
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Re: The Combined Lunesta (Eszopiclone) Experience Thread

Lunesta(Eszopiclone)definitely worked for swim.The only problem is the benzodiazepine like amnesia involved with it.It sucks waking up and not remembering when you went to bed or what you said or did before going to bed.
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Old 26-04-2008, 08:48
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Re: The Combined Lunesta (Eszopiclone) Experience Thread

Swims mouth tasted like a rusty tin can and vomit. Swim was prescribed 3mg for sleep, but that lingering taste made me stop (the taste lasted for a whole day). Swim's memory was shot too. bleh. Swim brushed, rinsed with listerine, brushed again, and gargled lemon juice which helped a bit.
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Old 26-04-2008, 17:42
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Re: The Combined Lunesta (Eszopiclone) Experience Thread

SWIM is suprised by some of these negative reactions. SWIM needs at least 4 mg to nod out, usually chased with a few shots of liquor, and has no aftertaste or amnesia. No hangover either. The only problem is sometimes it does not last long enough. SWIM does not use every day, but when SWIM does, SWIM has not experienced any withdrawals. It seems lunesta has a wide range of individual variation...
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Old 26-07-2008, 12:49
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Re: Lunesta (Eszopiclone) Experiences

When Swim tried Lunesta it made Swim feel absolutely stupid. Swim has tried Ambien several times and loves it. Lunesta also made Swim exhausted the next day until Swim needed to fall asleep.
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Old 26-07-2008, 13:18
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Re: Lunesta (Eszopiclone) Experiences

Lunesta(eszopiclone is more like a benzo where as ambien (zolpiderm) feels abit different from any other drug.No as swim as said before he would describe ambine(zolpiderm)as the psychedellic benzo.Thats what makes it such an interesting substance.
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Old 11-08-2008, 09:44
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Re: Lunesta (Eszopiclone) Experiences

Another thumbs down for Lunesta. SWIM found it more enjoyable than diphenhydramine/PMs, but less enjoyable than Ambien. No hallucinations over several nights, including a high dose >15mg. SWIM just felt slightly drunk and irresponsible. No full on blackouts, but a couple phone calls I didn't remember.

The taste afterwards really ruins it. It's only noticeable if one eats food. Some foods are more effected than others. Water tastes terrible.
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