Experimenting with 2x Explosion

[TranceAddict]

This event that will be discussed is of swims experience a little over
15 hours ago. Swim and his girlfriend went to a party last night and it
ended up being raided by the cops so Swim left early...swim and his g/f
decided to go to his house and do explosion (even though they did it
the night before at a party swim had at his house). swim and his g/f
took their first dose at 1a.m...each one consumed a vile. it went in as
normal. swim was worried taking it two days in a row would lower the
effects but it all seemed fine to swim when it kicked in. an enormous
amount of talking, of what swim and his g/f thought was important about
their lives went on...2 1/2 hours into the convo it was decided that
the both would lay off any drug use for 2 weeks to test themselves if
they were able to as they both saw an increase of usage this past month
(swim had tried 4 new drugs within the past month and her 5)... it was
decided that having 2 more explosion viles would be too tempting for
the 2 weeks and throwing it away would be a waste so it was decided to
consume another vile at 4a.m. and to instead enjoy it and not
talk so much as it was pretty much all swim and his g/f did the 3 hours
they were on it. lirally non stop talk and jumpin from subject to
subject. the communication was actually good, many things go across. it
was decided that for the second dose swim and his g/f would try to
enjoy it..listen to music..dance. give massages, etc. it was goin to be
taken 3 hours after first dosage (about the time it was wearing off).
it was a risk they both chose to do although swim didnt want his g/f to
be experimenting with the unknown. early into 4 a.m. it was
taken..not knowing what would happen. less than 15 mins later swim was
feelin really weird in a negative way....intense sensitivity more than
normal throughout the whole body. sweating and feeling cold and
shifting to havin goosebumps and feeling hot in short periods of time.
and feelin as swims memory would glow blank for short instances of
time. swims g/f got REAL bad...she first said she had a headach so swim
told her to sit down on the couch. she seemed as her whole body slowed
down. she started gettin worse and worse..swim didnt pannick (maybe
becuz he was in an altered state) but a concern was growing every
minute that passed. she started shakin uncontrollably. tellin swim she
saw 10 of him instead of 1.... she had increadible jaw clenchin and
tooth grinding. could barely talk due to the jaw clenchin. peices of
her teeth were literally being broken down (she said she felt it in her
mouth). she thought her silver filings in her teeth had broken apart
and swim doubted it until he actually looked into her mouth to be
astonished that it actually had broken apart. she was goin through bad
pain due to the jaw clenchin....swim ran and got a towel and put it in
her mouth. she chewed on that towel for the next 30 mins. swim
definately felt different, as if it was too high of a dose but not as
bad as her. he assumed it hit her worse because she is smaller in size,
weighs 107 pounds. swim was 'drugged' out but no where near as bad as
she was. her headach started goin away about after an hour from the 2nd
intake and about an hour and a half after the 2nd intake she was
dancing to the trance that was being played. she started trippin out
sayin she saw weird things (the lights were turned off and there was
flashes of light from a strobe light and the computer screen in the
livin room). swim kept tryin to snap her out of it but was unable to.
she seemed to be in her own world. she had to go check for herself to
make sure the things she saw wernt there even after swim told her she
was seeing things. swim was feelin slightly good, although he felt a
little bit of that being 'drugged' feeling but was mainly concerned of
his g/f's situation. she claimed to see strange things and swim was
unaware if it was her being overly joyfull (she was dancin around,
talkin a lot, basically it was hittin her real hard). the jaw clenchin
and teeth grinding continued throughout the night. by 6:30 in the
morning swim checked her mouth and both inner side walls were slightly
swollen and filled with cuts from her grinding her teeth on it.



to this moment she still has a headach that hits her and goes away and
has only been able to sleep 2 hours regardless of the fact that they
both didnt eat and stayed up all night (and slept about 4 hours the
night before from swims party). be aware that all this initially
occured about 15 hours ago and she still has side effects.



I've never seen anyone discuss about taking 2 explosion viles. The most
I ever came across was 1 and a half. BE AWARE that this was 2 viles
consumed a little over 3 hours from eachother. the effects were very
scary!!



The outcome of it all is swims girlfriend says she was scared as hell
last night but at the same time enjoyed it. regardless of this
fact...the effects occuring from a 2x dosage were bad. nothing like X
where u can pop 2 or 3 mdma caps within a few hours and not get as what
happened with 2 viles of explosion (methylone)





ironic of the issue...neither one has said that wouldn't take it again.
however it can be surely stated 2 viles in a row within a few hours
will never be done.

[Alfa]

The same can happen with MDMA caps if they are high dosed. I've read more accounts of people who where stupid enough(no offense ment)to dose two vials within a short timeframe. After I first tried explosion, it was very clear to me, that I would not dare taking two vials at once or shortly after another. 280 mg does do the trick. 520 is clearly in the no way zone to me. I find the reason stated to take another vial very strange. Please give your gf a lot of anti-oxidants and 5htp, with B6 for quicker recovery.

[nanobrain]

^hey SWIM, total overdose, 200mg is fine for most people, and 2 days in a row - you've done some serious serotonin receptor downgrading.

all in all, you got off easy, could have been much worse.

expect to be cracked out and depressed the rest of the week.

take magnesium to help with the muscle tension, load up on antioxidants, and 100mg 5-HTP before bed for the next few days - hey, Alfa just said that! although do not take B vits together with 5-HTP, will prevent it from crossing BBB.Edited by: nanobrain

[radiometer]

When I had the powder I found that 180mg was plenty for a good time.Edited by: radiometer

[BlueMystic]

^ Agreed. Anything over the 300mg mark in the same day is waaay too much.

[Alfa]

It is not the total amount that hits to hard, but the amount ingested within a short period of time. My friends and I have taken 2 vials or even more, but only in half vial doses, consumed with an interval of 4 hours minimum. Redosing with a whole vial was always punished by overstimulation.

[TranceAddict]

she has definatly been depressed since. swim had to go to her house
last night and try to calm her down with a 2 hour talk walkin around
her neighborhood because shes finding everything wrong. swim is taking
it alright.



do you guys think swim and his g/f suffered any damage? or will the
serotonin be regenerated? swim is buyin from 5-htp tomorrow. swim
thinks he's fine (atleast feels that way). swim felt normal at work.
what do you guys think?

[Tony Blair]

Originally Posted by nanobrain

take magnesium to help with the muscle tension,
load up on antioxidants, and 100mg 5-HTP before bed for the next few
days - hey, Alfa just said that! although do not take B vits together
with 5-HTP, will prevent it from crossing BBB.

Good advice.. Although I thought B Vits was necessary for 5-HTP to be
activated.. hence why the tablets in most health shops in the UK
contain both 5-HTP and Vitamin B.



Bottom line is, when it comes to drugs, less is more. You guys know you overdid it.

[TranceAddict]

Does anyone know if swim should take 5-htp with or without vitamin b? swim just bought 50mg 5-htp and 500mg b-12's today.

[Alfa]

You need B6 with the 5htp

[zipoo]

not sure about how to take the 5htp, but for future reference when something like that happens and a trip seems to be getting out of control, it would be advisable to have some kind of sedative on hand preferably a benzo. I once read a medical report that when one is having a really bad psychedelic trip doctors should first administer volume and if that doesn’t work should use some antipsychotic.

[drwoo]

Originally Posted by zipoo

I once read a medical report that when one is having a really bad psychedelic trip doctors should first administer volume

I assume you mean Valium?

[radiometer]

LOL

[nanobrain]

you know, i never did understand why many companies package 5-HTP w/B vitamins.

PHARMACOKINETICS OF 5-HTP:

A significant amount of an ingested dose of 5-HTP is decarboxylated in the small intestine to 5-hydroxytryptamine (5-HT or serotonin).

Carbidopa, if administered with 5-HTP, inhibits this decarboxylation which is catalyzed by a vitamin B6-dependent decarboxylase.

Peripheral decarboxylation of 5-HTP occurs to a much lesser extent in those with low vitamin B6 status, and most likely to a greater extent, in those who take concurrent vitamin B6 supplements of doses 5 milligrams or greater.</font>

The efficiency of absorption of 5-HTP, as well as its decarboxylation product serotonin, is approximately 47% to 84%. Absorption of 5-HTP occurs by an active transport process. 5-HTP is transported by the portal circulation to the liver where approximately 25% of an administered dose is metabolized via vitamin B6-dependent L-aromatic amino acid decarboxylase to 5-HT. 5-HT is subsequently metabolized to 5-hydroxyindoleacetaldehyde which is rapidly metabolized to 5-hydroxyindoleacetic acid (5-HIAA).

5-HTP that is not metabolized in the liver is transported by the general circulation to the various tissues of the body, including the brain.

thus, unless you want inactive peripheral serotonin, which does not cross BBB, no B vits for you.Edited by: nanobrain

[Gahaba22]

Nanobrain,

Thank you for the excellent post on B6 and concimittant 5-HTP ingestion

[radiometer]

nanobrain, thank you for posting that, I wanted to counter the statement
made earlier about B6, but I was too lazy to go looking for the references.

It is desirable to avoid peripheral serotonin production, which B6
supplementation encourages.

geeb, how does it feel to be referenced on Erowid? Edited by: radiometer

[zipoo]

Originally Posted by nanobrain

thus, unless you want inactive peripheral serotonin, which does not cross BBB, no B vits for you.

thanks for the informative post. would you know or care to guess how long one should wait for the 5htp to metabolize before taking the B and how long after taking b before taking the 5htp? Also does this apply to all B vit or to B6 in particular?

[nanobrain]

i believe it is specific to B6, but please correct me if i am wrong.

if taking a 100mg 5-HTP cap befor bed, i will just usually skip my multivitamin tab that morning - this is sufficient.