Combinations - Ssri and bad combo's?

[Shr00merized]

Swim wonder if it is any drugs he should keep away from when he is on ssri ?is it some drugs that could be very dangerues on ssri?please list up.I if he had stop with ssri ?how long should he wait until it is safe?

[Coconut]

Drugs which increase serotonin levels in the brain and monoamine oxidase inhibitors (MAOIs) should be avoided. They will increase the risk of serotonin syndrome, which can potentially be fatal.

SSRIs potentiate the effects of alcohol - one will feel drunker than usual.

Potential drug interactions should disappear once SWIY has stopped taking the SSRI. Remember that you should taper off, not stop immediately.


Taken from Wikipedia:

One major contraindication of SSRIs is the concomitant use of MAOIs (monoamine oxidase inhibitors). This is likely to cause severe serotonin syndrome.
People taking SSRIs should also avoid taking pimozide (an antipsychotic diphenylbutylpiperidine derivative). The atypical opioid analgesic tramadol hydrochloride (or Ultram, Ultracet) can, in rare cases, produce seizures when taken in conjunction with an SSRI or tricyclic antidepressant. Liver impairment is another contraindication for medications of this type.
SSRIs may increase blood levels and risk of toxicities of certain medications:

1. highly protein-bound medications like warfarin (coumadin) and digoxin
2. antiarrhythmic agents like propafenone (Rythmol) or flecainide (Tambocor)
3. beta blockers like metoprolol (Toprol xl) or propranolol (Inderal)
4. tricyclic antidepressants like amitriptyline (Elavil) (may increase risk of serotonin syndrome)
5. benzodiazepines like alprazolam (Xanax) or diazepam (Valium)
6. carbamazepine (Tegretol)
7. cisapride (Propulsid)
8. clozapine (Clozaril)
9. ciclosporin (Neoral)
10. haloperidol (Haldol)
11. phenytoin (Dilantin)
12. pimozide (Orap)
13. theophylline (Theo-dur)

Certain drugs may increase toxicities of SSRIs:

1. alcohol and other CNS depressants
2. diuretics (water pills)
3. MAOIs
4. sympathomimetic drugs like pseudoephedrine (Sudafed)
5. lithium
6. sibutramine (Meridia)
7. MDMA (ecstasy)
8. zolpidem (ambien)
9. Dextromethorphan
10. tramadol (synergistic serotoninergic effect said to increase risk of seizure)

[Jatelka]

Please try a search for "Serotonin Syndrome", you could also search the tag cloud for the same thing