Effects on rat sexual behaviour of acute MDMA alone or with loud music

[Potter]

Effects on rat sexual behaviour of acute MDMA (ecstasy) alone or in combination with loud music.

Cagiano R, Bera I, Sabatini R, Flace P, Vermesan D, Vermesan H, Dragulescu SI, Bottalico L, Santacroce L.

Department of Pharmacology and Human Physiology, Faculty of Medicine, University of Bari, Bari, Italy. r.cagiano@farmacol.uniba.it

The effects on sexual behaviour of acute low doses of methylendioxymethamphetamine (MDMA) (0.3, 1, 3 mg/kg/i.p.), alone or in combination with exposure to loud music (1 h stimulation), were investigated in Wistar rats. Results indicate that acute MDMA, at dose of 3 mg/kg, notably impaired copulatory behavior of sexually experienced male rats. In particular, MDMA-exposed animals exhibited a significant increase in intromission and ejaculation latencies as well as a significant decrease in percentage of rats displaying copulatory activity (one intromission at least). Surprisingly, one hour exposure to loud music, which per se resulted ineffective, antagonized the suppressive effect of MDMA by increasing the percent of animals displaying sexual activity. However, combined treatment of MDMA and music stimulation did not fully restore normal sexual behavior as the animals reaching ejaculation still showed a marked reduction of copulatory efficiency. These findings demonstrate that the systemic administration of a single low dose of MDMA, alone or in combination with loud music, which is commonly present in certain environments such as rave parties, notably impairs copulatory activity of male rats.

So MDMA diminishes rat's libido and playing loud music increases, but doesn't restore it.

Must have been a weird scene to walk in on, bunch of scientists sitting around watching a tiny rat rave/orgy. Sexy!

Reputation Comments on this post:

	fucking awesome thead ... lol
	intersting

[DXMBunny]

does this add up to why people wanna fuck at a rave? so does it work for humans too?

[ihavequestions]

LMAO. swim cant beleive scientists actualy did this type of study. it was like a controlled drug orgy for rats.

[Alfa]

Does the study distinguish between normal copulation and oral sex?

[old hippie 56]

Rats engaging in oral sex, well that a new one for me. Must be some happy rats.

[mbarnes0]

Haha. Makes those dudes wanna get down. I think that is really cool/strange that they actually studied this. Is there any info about what loud music does without the MDMA?

[Sven99]

The article doesn't go into the reasons for a reduction in copulatory activity. It could be that MDMA makes rats less inclined to fuck (maybe making them prefer to cuddle) or if it just impairs their ability to get it up. Very different effects, but the same overall outcome.