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  #1  
Old 09-12-2008, 22:20
killerfromsky killerfromsky is offline
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Solubility of methylphenidate hydrochloride?

Chemical Classification:
Organic Chemicals
Carboxylic Acids
Acids, Carbocyclic
Phenylacetates
Methylphenidate

Solubility:
A)
The solubility of methylphenidate hydrochloride in unbuffered aqueous solution at 32°C was found to be 191±6 mg/ml

B)
Experimental Water Solubility 1255mg/L
Predicted Water Solubility 1.82e-01 mg


Now how soluble is methylphenidate hydrocloride in water?
Is info A) correct?
What does info B) mean?

Both A) and B) can be found on the internet.

How many mg methylphenidate HCl can be dissolved in how many ml H20?
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Old 09-12-2008, 22:31
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Re: Solubility of methylphenidate hydrochloride?

B appears to be incorrect, at least in reference to the hydrochloride salt.
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Old 10-12-2008, 13:57
killerfromsky killerfromsky is offline
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Re: Solubility of methylphenidate hydrochloride?

Ok, also SWIM also had doubts about it not being about the HCl version.

How correct is A?
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Old 08-03-2009, 14:09
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Re: Solubility of methylphenidate hydrochloride?

Methylphenidate is pracitcally insoluble in water!!!
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