Acetaminophen question...

[Herbal Healer 019]

SWIM is a pretty skinny guy (145lbs. 5' 10''), although not out of shape, & is concerned about having consumed a total of 975mg-1625mg of acetaminophen 4x in 1 week. The doses of acetaminophen were only as high as 1625mg once and the other times were either 975-1300ishmg acetaminophen. Keep in mind tho that the doses were ussualy seperated by 650mg acetaminophen at once, then 2-4 hours later consuming 325mg more, and in some instances 325mg once every hour or 2 until a total of 1625mg was reached.

SWIM knows acetaminophen is worse for the liver and kidneys than almost all drugs (probably on par with alcohol), & thinks it's bullshit that this is the pharmaceutical companies' solution to anti-abuse considering the dangerousness of acetaminophen health-wise. People will abuse opiates & other drug preperations containing acetaminophen regardless of acetaminophen's prescence & widely known level of toxicity, so wtf?.

Anyways SWIM has only been consuming this much tylenol because the drug preperation they are taking (fiorcet) is hard as shit to do a CWE on, & is a process which involves hard-to-come-by/sketchy chemicals (sodium hydroxide & hydrochloric acid). SWIM likes the barbiturate high & wants to seperate the acetaminophen, but the traditional CWE apparently doesn't work well; so SWIM has decided to continue taking the drug with the tylenol prep. & wants to kno the danger of the pain-in-the-ass unwanted acetaminophen intake.

[tryptamaster]

well ur intake is within the acceptable levels. if u can reduce it in any way that wud be better. but id say ur not in any iminent danger.

[Herbal Healer 019]

SWIM cud, lol but they dont want to. The butalbital high is only really euphoric and enjoyable at doses of 100-200mg so 325mg acetaminophen, do tha math.

SWIM doesn't think their in imminant danger but thinks long term patterns of abuse like this cant be good for the health, especially when opiates & other substances are added to thee mix, as they often are for SWIM. Also SWIM only ways 145 on a good day & stands 5' 10"

Thanx 4 the response

[gmeziscool2354]

yeah, that seems pretty reasonable, just don't keep it up, cause you may have problems on down the way. I've never understood why APAP and asprin are still used so much today even after all the published literature on their liver toxicities.

Reputation Comments on this post:

good psot

[Jasim]

If swiy doesn't have any liver or kidney problems and doesn't mix it with anything else, swiy should probably be fine.

[Herbal Healer 019]

SWIM ussualy mixes it with buprenorphine & maybe less than a qtr of a cup of alcohol (17% irish cream) with cannabis or hydro and oxycodone, possibly alcohol & ussualy cannabis or either alone in combo with the acetaminophen-butalbital-caffeine prep.

SWIM plans on finding sodium hydroxide & hydrochloric acid in the near future to remove the acetaminophen through CWE in hopes of a more pure & cleaner barbiturate high. SWIM fears tho that some, if not significant amount, of the butalbital will be lost in the process. Any pointers in not losing butalbital in this modified CWE process?

[klonopinz]

swim wonders how swiy get his prescription. If legally, and with health coverage, just ask your doctor to give you an rx for a liver panel test.

if that is out of the question, well hospitals use acetaminophen (paracetamol) pretty aggressively, and you are actually taking what they would give if they only had tylenol to treat pain.

Maximum Daily Dosage is 4g, given at most 2 x 2g every 12 hours. However, it is rare to see liver damage unless some underlying illness is present even at 6g doses, as most minor acetaminophen overdose cases start at 8g in one single dose.

Swij should be careful, but not be so worried. He's actually being responsible.

[Herbal Healer 019]

SWIM obtained the script (fiorcet) in a 90 count bottle through an internet pharmacy within the country in which they live.

Can any1 recomend a place not a specific source where hydrochloric acid & sodium hydroxide would be obtained? and how sketchy would this look for a young dude to buy these materials?

[gmeziscool2354]

Hydrochloric acid can be purchased under the common name muriatic acid. sodium hydroxide is sold by the common name Lye. Muriatic acid is used in pools and spas, and Lye is drain cleaner.

or SWIY could ask a university student in a laboratory. guarantee if SWIY asks the right one they could help out

Reputation Comments on this post:

helpful

[Jasim]

Acetominophen is extremely toxic when mixed with ethanol. A chemical called Glutathione is required for metabolism of both ethanol and a metabolic deritivate of acetominophen (NAPQI) during second-phase metabolism. NAPQI is extremely toxic. Usually this toxicity isn't a problem because the body uses glutathione to metabilize it further into a non-toxic derivative and flush it from the body. However, when a person drinks ethanol glutathione is used up. When the body is depleted of glutathione, it allows time for NAPQI to accumulate leading to very high toxicity.

See these links for sources:
http://cat.inist.fr/?aModele=afficheN&cpsidt=13831683
http://en.wikipedia.org/wiki/NAPQI

EDIT: Actually many drugs are metabolized through the use of glutathione. Meaning that mixing acetominophen with all of the stuff swiy is mixing it with, would probably be sufficient to cause a risky depletion of glutathione.

Reputation Comments on this post:

	nice work
	you probably helped OP more than everyone else combined
	A very articulate and informative post.

[RoboCodeine7610]

Yeah, even though that dose is within acceptable levels if you mix it with alcohol even the smallest therapeutic dose could damage your liver so DO NOT MIX IT WITH ALCOHOL!