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Research Chemicals Piperazines, Phenethylamines, Tryptamines & other designer drugs.

 
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  #1  
Old 16-11-2008, 12:50
0utrider 0utrider is offline
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Etaqualone

hi
any information about this? couldnt find anyhting on erowid..
  #2  
Old 23-11-2008, 15:36
Mish Mish is offline
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Etaqualone

SWIM has recently managed to get ahold of 1g of Etaqualone and was interested in finding out some general (and more detailed chemical and biological) information about it. SWIM was hoping that by way of some of the SWIY-chemists residing on this forum, deductions could be made from the structural similarities between this compound and it's "popularized" cousin, Methaqualone (Quaaludes/Mandrax)...

Methymethaqualone (MMQ) did nothing for SWIM orally at 250mg - and SWIM didn't want to go above that for fear of the low seizure threshold - and, when 20mg was smoke, produced a short but distinctively dissociated rush of mild euphoria. SWIM's overall impression was not great.

However, SWIM has just come across this analogue Etaqualone. This, it seems, is much more likely to have an effect as it is structurally a lot similar to the original Quaaludes. Below is a comparison of chemical formulas for the analogues that seem to be available:
  • Methaqualone: 2-methyl-3-(2-methylphenyl)-4-(3H)-quinazolinone
  • Etaqualone: 2-methyl-3-(2-ethylphenyl)-4-(3H)-quinazolinone

    as opposed to

  • Methylmethaqualone: 2-methyl-3-o-tolyl-4(3H)-quinazolinone

SWIM is not particularly familiar with the chemistry of these structures, but is aware that the addition of the prefix 'Methyl-' in the MMQ analogue meant for supposedly faster absorbtion/onset; and that the 'o-tolyl-' addition also has the drawback of lowering the seizure threshold.

However, it seems that Methaqualone and Etaqualone are almost identical in structure, so it should thus follow that they should have near identical effects...? What differences occur to effects/bioavailablity when the -methyl group is substituted by an -ethyl group? (as in: '2-methylphenyl' for Quaaludes, and '2-ethylphenyl' for Etaqualone?

From SWIM's (admittedly very, very limited understanding), this would just mean a shorter duration of effects. Is this correct?

From 2 separate sources, SWIM has heard that:

Quote:
Depending on the structure they are attached to, generally ethyl groups shield neighbouring groups and make them less available than methyl groups. The longer the carbon chain, the more reactive the atom gets so adding an extra carbon to make an ethyl group would increase it's reactions.
This seems to be somewhat contradictory to SWIM. If the ethyl group shields neighbouring groups then subsequently Etaqualone should become less bioavailable than Methaqualone. If someone could relay the above information into laymans' term SWIM would be much appreciative.

There are little to no reports out on the 'net regarding Etaqualone experiences; presumably because it has only been fairly recently synthesized or - more likely - brought into the public eye.

SWIM is interested in the pharmacokinetics of this compound as he knows how popular Rorer 714's (300mg Methqualone in a capsule) were because in the 1960's and 70's, and was wondering how such a seemingly minor change can really alter the drugs effects...

However, being in possession of a small amount of Etaqualone means that SWIM is also most interested in the dose. SWIM has heard from other sights and reports that a dose of about 250mg orally produces a hypnotic sedating euphoria that lies somewhere between Diazepam and GHB - would this be true?

SWIM is considering both oral ingestion [250-300mg], inhalation [100mg], and insufflation [200mg] but would like to know which is the best. Bearing in mind SWIM has a naturally high tolerance to most GABA A receptor agonists (14mg of Clonazepam to feel anything; 60mg Diazepam; 160mg Temazepam; 80mg Zolpidem/Ambien) and, to a lesser extent GABA B agonists, where would a good starting dose be orally?

If anyone has had any experience with 'ludes in any form then please post them, as DF seems to be lacking in subjective experience reports that actually go into details about the dosages and explicit effects.

Thanks

EDIT - Even though this is a thread is really looking for guidance and general 'Drug Info' on the compound, SWIM is aware that it may have been placed in the incorrect sub-forum of the board. If so, please feel free to move it.

Post Quality Evaluations:
good info

Last edited by Mish; 23-11-2008 at 15:48. Reason: many
  #3  
Old 25-11-2008, 10:26
Synesthesiac Synesthesiac is offline
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Re: Methaqualone (Quaaludes)

Dont know if this should be here or in the research chems section. There appears to not be any decent report of Etaqualoneusage dosage and effects anywhere on the internet, but a popular online vendor has just got a lot of this in stock, so no doubt there will be a good few reviews about soon.

From the very few reports I've read, some say Etaqualone is very similar to its illegal analogue Methaqualone but has a much shorter duration, and some people claim no effects at all. But they may have got it from a dodgy vendor selling flour. You never know. And apparently it may not be very water soluble, so it may not be as effective nasally as orally, but this is based on only hearsay at this point.

Keep us posted if swiy does it. And with something this new and unknown its always a good idea to start very small. Even at 1-5mg to test for allergic reactions.
  #4  
Old 25-11-2008, 10:48
Synesthesiac Synesthesiac is offline
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Re: Etaqualone

Cant find anything about this one, and swim has the oppertunity to get it but doesn't want to waste his money on something that no-one seems to have written up about yet. Theres been a couple of reports on various boards over the last day or so, as this one seems to have literally just been rediscovered by some company last month, but no full reports with any of the vital info you would want to get. I doubt its going to be as good as its illegal analogue Methaqualone, but the effects will probably be similar, you'll probably just need more to get the same buzz.

One I found written literally yesterday:
Quote:
200mg insufflated a few moments ago. Completely empty stomach.

Almost no pain whatsoever, just a bit of stinging plus the fact you can feel a bulk amount of congealing powder in your nostril(s).

T+0:05 - Nothing. [....]

Okay well - nothing. Nothing at all. Not a single thing.
I will try 500mg oral tomorrow but if 200mg insufflated does nothing then I have little faith Shame.
Maybe its not active nasally? Or maybe you just need more than that. There seem to be quite a few people saying its not active at all.

And one more written today:
Quote:
The etaqualone I took was great. Felt very close to real methaqualone and about a similar dosage too. Just lasted shorter than regular MQ if my memory serves me correctly. I like it so much I'll probably be getting more of this stuff soon before they make it illegal here or something.
And thats all I could find. There will no doubt be a good few more about in the coming weeks though, but swims definately gonna wait until some more detailed reports are out.

Last edited by Synesthesiac; 25-11-2008 at 11:06.
  #5  
Old 25-11-2008, 11:25
Mish Mish is offline
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Re: Methaqualone (Quaaludes)

SWIM tried 200mg nasally last night (after 1mg to test for allergic reactions). No effects whatsoever.

SWIM will try 500-600mg orally tonight and see what happens. SWIM is aware of rapid tolerance developing so reckons this dosage would normally equate to 300-400mg orally (assuming no tolerance).

SWIM will report his findings later on; perhaps doing some form of live report as the 'net is severely lacking in subjective experiences...
  #6  
Old 25-11-2008, 11:54
Synesthesiac Synesthesiac is offline
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Re: Methaqualone (Quaaludes)

Swiys experience seems exactly the same as some other guy I read elsewhere who did 200mg nasally and got nothing. There is another thread about this stuff in the RC section where I posted the only two brief experiences I found for Etaqualone; http://www.drugs-forum.com/forum/showthread.php?t=71586 They are both conflicting, one says nay, and one says yay, but they dont give any detailed information at all really.

What would be good is a way to test this stuff to see if it really is what people think they've got, but I dont have a clue how that could be done.

Last edited by Synesthesiac; 25-11-2008 at 12:02.
  #7  
Old 25-11-2008, 14:55
0utrider 0utrider is offline
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Re: Etaqualone

Quote:
Etaqualone was inactive even at a bioassay dose of 750mg.
but i kinda doubt that it isnt active at all.. why would it be available then? the place where its from is usually very very reliable
  #8  
Old 25-11-2008, 14:56
0utrider 0utrider is offline
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Re: Methaqualone (Quaaludes)

yeah would be nice if SWIY could post his experiences in that post.
  #9  
Old 25-11-2008, 15:06
Herbal Healer 019 Herbal Healer 019 is offline
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Re: Methaqualone (Quaaludes)

For what ligitamate reason were quaaludes completely banned from pharmaceutical production? was it simply high instances of abuse?

In that case, y havent pharma companies completely banned opiates, amphetamines (including meth or desoxyn), & benzos, which all are commonly abused, but like quaaludes have legit medical purposes?

Did benzos replace ludes?
  #10  
Old 25-11-2008, 15:31
0utrider 0utrider is offline
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Re: Methaqualone (Quaaludes)

yes they did, as they replaced barbiturates, prolly because the LD50 was a lot higher with benzos. it was quite easy to kill oneself with the others
  #11  
Old 25-11-2008, 16:21
Mish Mish is offline
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Re: Methaqualone (Quaaludes)

Quote:
Originally Posted by Synesthesiac View Post
Swiys experience seems exactly the same as some other guy I read elsewhere who did 200mg nasally and got nothing. There is another thread about this stuff in the RC section where I posted the only two brief experiences I found for Etaqualone; http://www.drugs-forum.com/forum/showthread.php?t=71586 They are both conflicting, one says nay, and one says yay, but they dont give any detailed information at all really.

What would be good is a way to test this stuff to see if it really is what people think they've got, but I dont have a clue how that could be done.
Hahah, the negative quote is SWIM under a different name Which site was that from? BL? CHL?

SWIM will be taking 600mg in 30 minutes.
  #12  
Old 25-11-2008, 16:28
0utrider 0utrider is offline
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Re: Methaqualone (Quaaludes)

please report back, SWIY!
  #13  
Old 25-11-2008, 20:32
Mish Mish is offline
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Re: Methaqualone (Quaaludes)

Nothing. SWIM took a total of 800mg on an empty stomach with no effects. Really annoying.
  #14  
Old 25-11-2008, 20:43
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Re: Methaqualone (Quaaludes)

what.. that IS strange..
  #15  
Old 04-12-2008, 13:34
rocksmokinmachine Gold member rocksmokinmachine is offline
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Re: Methaqualone (Quaaludes)

Quote:
Originally Posted by Mish View Post
Nothing. SWIM took a total of 800mg on an empty stomach with no effects. Really annoying.
Very strange indeed, etaqualone is structurally similar (almost indentical infact) to methaqualone.

It would be interesting if someone who knows a little more about chemistry than SWIMself to comment on this, and perhaps provide an explanation as to why this may have happened.
  #16  
Old 07-12-2008, 22:17
Mish Mish is offline
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Re: Methaqualone (Quaaludes)

SWIM is guessing it is some personal enzyme deficiency, although others have reported almost no effects as well. SWIM is giving up on the Quinazolinone family, as it just doesn't seem to be working for him...

Shame, as SWIM thought it sounded like the perfect downer tailored for him.
Still, any SWIY's out there who've tried this stuff - please report. It's always good to have other subjective info...
  #17  
Old 12-12-2008, 10:04
rocksmokinmachine Gold member rocksmokinmachine is offline
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Re: Methaqualone (Quaaludes)

After time spent in South Africa (Jo'Burg), SWIM came across 'Mandrax' being sold on the street. After unwrapping the package the pills were stamped and colourful (as ecstasy tablets would be), he thought he'd been ripped off.

After doing a little research he came across something like this site.

xxxx

I think this was actually the site, ehh. SWIM's experience (smoked), as seems to be the most common method of injestion over there. Was FANTASTIC. Being a lover of benzo's, and barbs. This was one of the best things SWIM has ever felt. It was like a huge RUUUUUSHHH that floored him, he Can't remember much after that.

Last edited by Alfa; 11-10-2009 at 13:48. Reason: dead link
  #18  
Old 12-12-2008, 10:16
Synesthesiac Synesthesiac is offline
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Re: Methaqualone (Quaaludes)

Quote:
Originally Posted by rocksmokinmachine View Post
I think this was actually the site, ehh. SWIM's experience (smoked), as seems to be the most common method of injestion over there. Was FANTASTIC. Being a lover of benzo's, and barbs. This was one of the best things SWIM has ever felt. It was like a huge RUUUUUSHHH that floored him, he Can't remember much after that.
Swim would always be scared of smoking something due to the risk of it creating new unwanted particles that are harmful that wouldn't otherwise be there if swallowed of sniffed. But thats just swim.

This is interesting, maybe this is like DMT, not active hardly at all when swallowed or sniffed but only when smoked. Wouldn't have a clue why this is the case though.
  #19  
Old 12-12-2008, 10:18
rocksmokinmachine Gold member rocksmokinmachine is offline
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Re: Methaqualone (Quaaludes)

Quote:
Originally Posted by Synesthesiac View Post
Swim would always be scared of smoking something due to the risk of it creating new unwanted particles that are harmful that wouldn't otherwise be there if swallowed of sniffed. But thats just swim.

This is interesting, maybe this is like DMT, not active hardly at all when swallowed or sniffed but only when smoked. Wouldn't have a clue why this is the case though.
DMT needs and MAOI (monamine oxidase inhinbitor), to work orally. Basically MAOI is an enzyme which breaks down serotonin in the brain.

Last edited by rocksmokinmachine; 17-10-2009 at 09:03.
  #20  
Old 16-12-2008, 04:59
DcJack DcJack is offline
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Re: Etaqualone

Ofcourse REAL Ethaqualon are active, it was sold in many european countries before as a legit medical. So that can't be real Ethaqualone if it isn't active at all.
  #21  
Old 28-07-2009, 18:50
Codehead Codehead is offline
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AW: Etaqualone

So has anyone got succeful try outs with this one? Seems interesting chemical.
  #22  
Old 23-08-2009, 21:15
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Re: Etaqualone

My Buddha statue tried 603mg last night to no effect, smoked 115mg for a slight rush for 5 min that's it. Not worth the money.
  #23  
Old 30-08-2009, 20:29
Mish Mish is offline
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Re: Etaqualone

603mg is a high dose... SWIM was wondering (as it has been such a while since his pet giraffe ventured into Methaqualone analogue-territory): is that a high dose/borderline seizure-risk...? Or would that be normal?

SWIM's friend remembers issues with MMQ and potential for seizures - not that any problems ever arose - but he remembers getting nothing from Etaqualone, even though it's supposed to be a closer and thus more potent analogue, but didn't want to push the boundaries too far.

Was SWIY's Buddha aware if this was an "old" batch or a possible "new" batch of EQ; as the "old" was renowned for having issues with purity and efficacy, or so SWIM heard...?
  #24  
Old 02-09-2009, 18:15
DynoMiTe DynoMiTe is offline
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Re: Etaqualone

It was a new batch from a different vendor, he started stocking it about a week before I bought it and to my Buddha's knowledge never stocked it before.
  #25  
Old 23-09-2009, 23:06
Codehead Codehead is offline
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AW: Etaqualone

SWIM has tested this with doses 400-500mg, and found that 500mg is good dose. Also he has combined it with codeine, ephedrine and weed, it has great synergy with all of them. Its way too expensive for one dose, but he likes it.

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