Purity - Freebasing LSA

[twitehell messenger]

joe was wondering is it possible to freebase lsa that has gone through a non polar/polar extraction simply by basing the water in the polar stage (after defat) and extracting with a non polar to be left with pure hbwr alkaloid crystals? is this even the right way to go about it? if so what would the best 2nd non polar to use be? joe asked me to post this just because he doesnt like playing with the gunk and finds it hard to disolve into alcohol for long term storage. he thought with freebase crystals there would be a smaller amount of product to work with and that it would also be more easily disolved in a smaller amount of alcohol. also for wieghing purposes for acurate dosage.

any help would be greatly apreciated and a picture guide tek would also be made to help others achieve this.

[twitehell messenger]

ALKALOID EXTRACTION
The Stat-Otto process is a method which exploits the property that simple salts of many alkaloids are watersoluble but much less soluble in organic solvent, wheraes the reverse is true for the free bases. The technique involves the distribution of the bases between the acid and alkali aqueous and immiscible organic solvents.
Dried powdered plant material is moistened and made alkaline with for example sodiumcabronate (Na2CO3), potasiumcarbonate-ammonia (K2CO3NH3) or calciumhydroxide (Ca(OH)2). You could use other chemicals to make an alkali aqueous solution. The alkaloids are now in there free basic form. Now add the organic immiscible solvent for example cloroform (CHCl3), ether (di-ethyl ether (C2H5OC2H5)) or methylene dichloride (CH2Cl2). You could choose for a different solvent, one you can buy in the stores like petroliumether, only you must thake in consideration that there is a possibillity of the solvent not being pure and therefore might leave a residu after evaporation. The two layers must be mixed thoroughly to get the free base into the solvent. The two layers, obtained after letting them unmix again, can be separated with a separatory funnel from which you can tap off the bottem water-layer (highest density) and the top organic-layer with the free basic form of the alkaloids. The organic-layer is concentrated by evaporating a bit of the solvent. Next step is to add dilute sulphuric acid (H2SO4) to extract the alkaloids into the aqueous layer because they are now agian in there acidic form. The two layers must be mixed thoroughly and left alone to unmix again. The two layers can then agian be separated in the separatory funnel from which we now keep the aqueous layer. The alkaloids are now in there acidic form in the water. The organic-layer contains pigments, fats, weak bases and alkaloid sulfates who are soluble in the used solvent. Make aqueous solution alkaline and add fresh solvent and shake thoroughly to make the free basic form go into the organic solvent. Separate in the separatory funnel and keep the organic-layer and let the solvent evaporate. The crude alkaloid mix is obtained.


Will this be effective in retrieving a crystal result that could be weighed accurately? If defatted enough times I imagine that it would but if anyone can help out please do i just want to know if its worth it to make a 100ml bttl of ethanol/lsa mix from 500 seeds as its not really possible with the goo i would get.

[darkbreed]

Is there any way to precitipate LSA in a solvent? If so what method and what chemicals would be needed for this? For example if you have water and add a base like sodium carbonate to it, would this make the lsa base precipitate out from the solution? Thus the solids could simply be filtered out and saved and discard the water instead of using both polar and nonpolar solutions and messing around with removing one layer etc.

Perhaps it is also possible to freebase the LSA/LSA by adjusting to correct PH and at the same time not freebase the toxins, and then extract the freebased LSA/LSH by filtering out in something it would stay solid in while the toxins are soluble?

Any dogs or cats that got some experience and knowledge on any or all of these questions would be appreciated to get some input from.

Did anyone ever try to smoke LSA in either pure or freebased form and if so did this produce any effects?

Some more input on this thread would be interesting, surely there must be someone out there whom have experimented some with this?