Experiences - MDPV -- tolerance and withdrawal???

[konshuss]

SWIM needs some help/input please...

Background:

SWIM is relatively healthy, generally takes care of himself. Not a regular user of any drugs besides caffeine, melatonin (sleep-aid), and occasional alcohol.

SWIM started using MDPV as a study/work aid recently. Loved the effects. Kept dosages low-ish out of respect for the body & the chemical. ("Low-ish" being subjective, I know...)

In the past 7 days, SWIM has used MDPV almost daily. No redosing, no screwing around. Just a single 6mg oral dose at mid-day to help keep momentum going. Very productive during the day, no trouble sleeping at night. Multivitamins and antioxidants daily as preventative.

Since the end of that recent session, the past couple days have been strange. SWIM tried same 6mg dose of MDPV 3 days ago, and was surprised to find SWIM barely felt any effects!

SWIM felt it was like the equivalent of 1 cup of strong coffee, but that was it. Previously, this same dose would put SWIM into a energetic and productive head-space for about 4-5 hours with gentle come-down. But not any more.

The following 2 days SWIM has been lethargic, lacking energy, having some difficulty focusing, just wanting to sleep much more than usual.

God is this really happening? SWIM tried a 4mg dose again today -- same thing. Very minor effects, almost non-existent. A cup of coffee was better at clearing the cobwebs.

Is SWIM dealing with dopamine depletion? If that's what it is, SWIM really really doesn't like it. AT ALL.

Any thoughts or suggestions would really be appreciated!

[sweetsweetmary]

Originally Posted by konshuss

SWIM needs some help/input please...

Background:

SWIM is relatively healthy, generally takes care of himself. Not a regular user of any drugs besides caffeine, melatonin (sleep-aid), and occasional alcohol.

SWIM started using MDPV as a study/work aid recently. Loved the effects. Kept dosages low-ish out of respect for the body & the chemical. ("Low-ish" being subjective, I know...)

In the past 7 days, SWIM has used MDPV almost daily. No redosing, no screwing around. Just a single 6mg oral dose at mid-day to help keep momentum going. Very productive during the day, no trouble sleeping at night. Multivitamins and antioxidants daily as preventative.

Since the end of that recent session, the past couple days have been strange. SWIM tried same 6mg dose of MDPV 3 days ago, and was surprised to find SWIM barely felt any effects!

SWIM felt it was like the equivalent of 1 cup of strong coffee, but that was it. Previously, this same dose would put SWIM into a energetic and productive head-space for about 4-5 hours with gentle come-down. But not any more.

The following 2 days SWIM has been lethargic, lacking energy, having some difficulty focusing, just wanting to sleep much more than usual.

God is this really happening? SWIM tried a 4mg dose again today -- same thing. Very minor effects, almost non-existent. A cup of coffee was better at clearing the cobwebs.

Is SWIM dealing with dopamine depletion? If that's what it is, SWIM really really doesn't like it. AT ALL.

Any thoughts or suggestions would really be appreciated!

SWIM would just chalk it up to another side effect of this terrible chemical. SWIM would never dose this chemical in back to back days or back to back weeks for that matter. Maybe take a month or two off and see if SWIM enjoys then. If not joy, bye bye MDPV, addiction has taken hold. Same thing happened to SWIM when he was in the depths of deep coke binders, Cocaine would just cease to provide any positive effects and have all the negatives times 10. Ask any crack head how much joy is obtained from continuing crack usage. Just my thoughts...

[snapper]

Yes there is a tolerance. SWIM would use for 3 - 4 days straight and the last day would require triple dosing to get the same effect. The duration of action gets progressively slower with each day as well. SWIM decided to make it an occasional thing after that. However, SWIM gets really unfocused on the stuff and would not be able to use it to do anything productive, so it is easier to space out doses. I does deplete dopamine like any other drug in its class and the fatigue reflects that. As far as addiction is concerned, SWIM has never used long enough to find out and does not like to go past 15 mg in a day due to unpleasant side effects. Below that SWIM is fine.

[Euphoric]

If SWIY wants to replenish dopamine a tyrosine supplement would be helpful.

[konshuss]

Euphoric/Snapper/Sweetsweetmary,

SWIM would like to pass on his sincere thanks and gratitude for your posts. Really appreciate you taking the time to write.

Heading into day 4 of avoiding the MDPV. SWIM is * slowly * starting to feel better.

What is surprising is the desire to sleep all the time! During the day, it's tough to resist a nap (responsibilities do not allow this) ... and general fatigue.

Self-medicating with caffeine is not doing much of anything.

SWIM is really wondering still ... could this be the MDPV? Could physiological problems arise from only a handful of consecutive daily doses?

It wasn't like SWIM was over-doing it, or bingeing. Quite the contrary -- just moderate doses once a day. But there definitely was a HUGE drop-off in effectiveness after a few days, like "the magic had disappeared". And then stopping MDPV altogether coincided with SWIM's current lethargy and ill-feelings...

SWIM also must admit that there is a small amount of jonesing going on. He thinks: "God I feel like sh*t, I'm not being productive today at all. A 5mg dab of MDPV wouldn't hurt, would it?" SWIM has had to resist this a couple times. He doesn't want this to become a daily ritual.

SWIM will let a couple more days pass then re-try a moderate dose. Big project is coming due in 2 weeks, must prepare...

Reputation Comments on this post:

You're welcome, thanks for sharing the experience, hope SWIY feels better soon.

[RaverHippie]

often times people regard research chemicals as tools only to be used sparingly, no matter what the effects of the drug may be. This allows the brain chemistry to return to normal and prevents the build-up of a tolerance. The rule I hear most often reported with RC's is minimum of a week between doses. Nothing is ever sustainable enough to be taken daily as far as I know so far (that's why they're called research chemicals!) but judging the similar mechanism of action for many chemicals, something inevitably becomes depleted so it would be interesting indeed to find a "once a day" RC.

While SWIY regards the dosages outlined in the OP as not a binge, in a way it was a binge in frequency of the dosages.

[sweetsweetmary]

As far as SWIY's sleeping problem, SWIM could barely lift his head for a week after his first usage. Tiredness filled his every waking moment and body aches and thoughts of mdpv disgusted him. The comedown off MDPV is wretched for lack of a better word, and this drug felt as gross as methamphetamine, if not worse!

[snapper]

There must be something wrong with the MDPV circulating right now. SWIM does not even notice the stuff wearing off and wishes it would last longer! what kind of dose range is SWIY using ? SWIM never exceeds 15mg in a night and usually doses incrementally 2 mg at a time sublingually to effect, then hourly bumps to keep it going. MDPV is difficult to synth, so maybe some of what is around is adulterated.

[konshuss]

UPDATE: SWIM's kitty cat took 5mg MDPV today, orally at 1045am, effects were 100% "engaged" at 1130am.

Back to the good ol' days! Ahead Warp Factor 8, Mr. Sulu!

All of the positive effects were felt (clear mental energy, good body energy, mood lift, positive focus, drive to "get things done") ... SWIM's kitty reported no bad effects.

It's 230pm (T+4 hours) and SWIM's kitty is in a good headspace, things have leveled out now from the initial rev-up. Kitty will probably use some melatonin or HTP to put the brakes on at bedtime.

ABOUT THE BATCH: well, SWIM is not an organic chemist ... God if I know H20 from dihydrogen oxide. Anyways, the batch my kitty has is #1 made in China #2 pure white, fluffy happy-looking white stuff. Not crystalline, more like very fluffy fine clumpy powder. Very faint odour, sort of like a strange mutant mint smell. Taste is very bitter, more of that weird mutant wintergreen smell when ingested.

It would not surprise SWIM if other people's MDPV would be malodorous or ill-coloured. There are pix circulating around the interweb of brownish crystalline MDPV that looks nothing like my kitty's.

SUMMARY: SWIM's enjoyment of MDPV continues, the previously reported physiological f/x may or may not have been caused by MDPV tolerance. Instead, SWIM is going to be respectful and sparing in his use of said RC.

Reputation Comments on this post:

Thanks for the update

[konshuss]

UPDATE #2: Kitty has been using low oral doses (around 4-6mg) every day this week, to help in energy and concentration. As long as the last dose is administered before 3pm my kitty doesn't complain of insomnia.

INTERESTING SIDE NOTE: Yesterday, kitty knew that he was going to be getting some sexy action with his wife-cat, so he also took 10mg of generic Levitra to throw things into high gear "down there".

Two hours later, some strange, mild side f/x, probably due to mix of caffeine, MDPV, Levitra and red wine. Pulsating vascular retina action going on in the field of vision. Not worrisome, but there was a steady pounding of the heart (around 85bpm, +15bpm over baseline of typical 70bpm) and the wiggly lines ... prob due to increase in blood pressure?

Again, not really worried, the kitty is in really good health otherwise, non-smoker, exercises regularly etc., but this is a drug interaction that kitty told me to be aware of.

Can't really say that kitty is much of a fan of Levitra or other ED drugs...fun once in a while but that's it. But that's another story.