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  #1  
Old 20-10-2008, 16:56
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What's best for tramadol comedown, soma or benzo?

Having had 150 mgs of Tramadol in the last 5 hours, I would like to have a soft landing with a downer.

What's best for this, some clonazepam or soma?

And if you could recommend a dose for each, I'm thinking 0,5 clonazepam, but would like to go higher if anyone has any experience with it.
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Old 20-10-2008, 17:28
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Re: What's best for tramadol comedown, soma or benzo?

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Originally Posted by wings of wax View Post
Having had 150 mgs of Tramadol in the last 5 hours, I would like to have a soft landing with a downer.

What's best for this, some clonazepam or soma?

And if you could recommend a dose for each, I'm thinking 0,5 clonazepam, but would like to go higher if anyone has any experience with it.

Swim says the kolonpin would help but the thing is that swim needs to make sure that it has been atleast 6 hours since any of the drug was ingested. Others might disagree with this but the mixing of high doses of opiods and benzos can be dangerous. So if swim is convinced that most drug is out of the body then swim would take two kolonopin to comedown.

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Old 20-10-2008, 17:50
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Re: What's best for tramadol comedown, soma or benzo?

150 mgs of Tramadol is far from being a "high dose", and 0,5 mgs of Clonazepam (Klonopin, not "kolonopin") is a very low dose too.

I've read many posts that recommend taking a small dose of clonazepam or diazepam in order to smooth out the tramadol experience, but because some people have a tendency to parrot warnings they read on Wikipedia without having any direct experience with the combination, I have had so much conflicting information that I don't know what's true.

I know you shouldn't mix downers, but mixing 0,5 clonazepam with a medium-low dose of tramadol should be completely harmless, to the best of my knowledge. However, when people scream "IT'LL KILL YA JUST LOOKING AT IT!" at every opportunity they get, it gets to me.

What I am trying to say is, we need to accept that people mix downers all the time, and in order to give the best possible information, we need to keep this in mind, and not simply dismiss the idea without contemplating it, or acknowleding the fact that so many people have experience mixing them without any problems.

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Old 20-10-2008, 22:44
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Re: What's best for tramadol comedown, soma or benzo?

How is Swiy having a comedown from tramadol, much less at that dose?
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Old 21-10-2008, 00:11
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Re: What's best for tramadol comedown, soma or benzo?

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Originally Posted by fiveleggedrat View Post
How is Swiy having a comedown from tramadol, much less at that dose?
This is what my monkey is wondering. He finds himself in a cheery, or mildly apathetic at the least, mood as the Tramadol's effects wear off and doesn't notice much in the way of 'comedown' symptoms at all.

A bit of benzo could add some nod and make the comedown altogether unnoticeable for swiy, but I would be highly wary of what doses one is taking and would keep in mind that Tramadol's risk is much higher when mixing it with other substances. My monkey would be even more inclined to leave carisoprodol (Soma) out of any Tramadol combination given that he isn't sure how / if it would potentiate the Tramadol and he wouldn't want synergistic sedative effects giving him problems with respiratory depression, which Tramadol is known for.



Also, Wings of Wax, please refrain from incriminating yourself when posting on these forums. Read over the rules and forum faq (easily found near the top of your screen) to make sure you understand forum protocol before posting further. Thank you.
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Old 21-10-2008, 07:47
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Re: What's best for tramadol comedown, soma or benzo?

oops, swim really needs to remember that this concerns swim, and nobody else. Sorry.

When swim says comedown, he means that slightly jittery-skitzo feeling that tramadol sometimes can give you, not a comedown like on stimulants. Swim did take 1 mg of clonazepam after the tram, and that made him relax perfectly.

So swim guesses you won't recommend a low dose of soma either, together with the tram? Soma is well known to potentiate opiates, and since it has been widely used with opiates that depress respiration much more than tramadol (all the real opiates), swim would think that the combination is ok. But swim isn't stupid; he would only do it if someone was to tell him that they have experience with it, and that the combo is good.
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Old 21-10-2008, 08:06
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Re: What's best for tramadol comedown, soma or benzo?

Clonazepam could help with Tramadol's propensity to lower the seizure threshold and maybe ameliorate some uncomfortable comedown effects. My monkey would stick to low doses to achieve the desired result, and he would be much more wary of doing this if the dose of Tramadol were higher than aforementioned.

I don't know the overall prevalence of Tramadol use or how much it has grown in recent years (could probably find some data if necessary), but my monkey doesn't think it is so widely (ab)used that there is much research on it. The manufacturer pushed it as a non-addictive alternative to current opioid medication, so I'm not sure how inclined the monkey would be to trust that we really know everything about this med.

There doesn't seem to have been much in the way of Tramadol related fatalities, but it does seem to be the case that most of the fatalities were resultant of combining Tramadol with other CNS depressants so my monkey will avoid doing so as much as possible (and it isn't that hard as Tramadol alone does the trick for him with acceptable risk).


Some data (perhaps there is also some newer research available):

Fatal overdoses of tramadol: is benzodiazepine a risk factor of lethality?

Abstract: Tramadol is a centrally acting analgesic agent used in the treatment of mild to moderate pain. It has a low affinity to opioid receptors and inhibits the reuptake of norepinephrin and serotonin producing an analgesic action by blocking nociceptive impulses in the spine. Although 21 drug-combined fatalities including tramadol have been reported, only two fatal overdoses in adults with tramadol alone have been reported to date. We report four additional lethal intoxications, assess the toxicity of tramadol, the detection method and the possible interaction with other central nervous system (CNS) depressants, particularly benzodiazepines. Similarities between tramadol and buprenorphine are discussed, and a possible cytochrome P450-based interaction between tramadol and benzodiazepine is considered. To our knowledge, this relationship has never been reported in the literature.


Fatal unintentional intoxications with tramadol during 1995–2005

This study examined fatal unintentional tramadol intoxications among Swedish forensic autopsy cases between 1995 and 2005. All fatal intoxications were selected, in which toxic concentrations of tramadol (>1 mg/g femoral blood) had been detected, and where the forensic pathologist considered the intoxication unintentional and the fatal outcome at least partly explained by tramadol. Toxicology analyses, police reports, autopsy protocols and medical records were scrutinized. A total of 17 cases (eleven men and six women) of fatal unintentional tramadol intoxications were identified.
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Old 21-10-2008, 09:15
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Re: What's best for tramadol comedown, soma or benzo?

I agree that high dose-combinations with tramadol and benzos should be avoided. What I am interested in is combining a low dose ( <=200 mg) of tramadol with a low dose of carisoprodol (=<375 mg), alternatively a low dose of clonazepam ( <=1 mg).

I have read some reports from user Delphinen, who seems to be very experienced in using these substances together with succes.
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Old 21-10-2008, 15:22
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Re: What's best for tramadol comedown, soma or benzo?

Depending on SWIM's tolerance this can either be a high,low or just fine dose for SWIM.SWIM should not base his intake on others experiences.If SWIM does decide to try this out then as always start slow amd move up or down as needed.Stay safe!!

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Old 21-10-2008, 15:35
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Re: What's best for tramadol comedown, soma or benzo?

Quote:
Originally Posted by wings of wax View Post
Having had 150 mgs of Tramadol in the last 5 hours, I would like to have a soft landing with a downer.

What's best for this, some clonazepam or soma?

And if you could recommend a dose for each, I'm thinking 0,5 clonazepam, but would like to go higher if anyone has any experience with it.
SWIM agrees with most that combining chemicals could be dangerous. SWIM says that with Tramadol in this low of a dose SWIY should have no major "come down". Hell, get some sleep. SWIM says always use caution.

-Pope Albacore
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  #11  
Old 21-10-2008, 15:46
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Re: What's best for tramadol comedown, soma or benzo?

Swim never had a comdown of tramadol even when taken 500mg, Please dont do the same !! Swim had a tollerance when he was taken 500mg in one go and sometimes more later.. When abusing tramadol and suddenly stop, the withdrawl is not nice trust swim !

Swim gets withdrawl after DF118 (diyhydrocodeine) Even in small amounts 120mg range.
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