Oral use - Chewing Opana ER 20 mg?

[Be]

If swim chews up an opana 20 mg er pill can swim get past the time release mechanisms?

[scribe_of_the_unthinkable]

Chewing up any ER tablet should bypass the time-release mechanism. Pharmacies usually provide specific instructions when they dispense these meds (ER or SR, that is) which state that one should not chew or crush up the tablets. If the tablets are chewed or crushed, you would receive the full dose of medication all at once, rather than over time. Hope this helps.

[Be]

Swim bit one in half and it did nothing. Swim will try to chew it up next time.

[crunchyblack]

Your wasting your time trying to take oxymorphone orally. Only 10% is absorbed orally. And when the pill hits water it will gel.

[MEKONE]

In SWIMS oppinion the ER's are not as good as th IR's.As stated above they turn to jell and thats to prevent IVing.However SWIM has sucked on a few and then chewed them up with decent results.But as stated before the IR's are much better than the ER's in SWIMS oppinion.

[Be]

Originally Posted by MEKONE

In SWIMS oppinion the ER's are not as good as th IR's.As stated above they turn to jell and thats to prevent IVing.However SWIM has sucked on a few and then chewed them up with decent results.But as stated before the IR's are much better than the ER's in SWIMS oppinion.

ER's were the only thing that swim could get right now.

So this is how swim figured out a way to do ER's orally and still give her euphoria. SWIM first takes a small blade or a razor and gently scrapes off the outer coating of the ER pill then she is lefy with only the while part on the inside. Swim then will crush it up with her teeth but only her front teeth because if the back teeth are used then it will stick in the grooves and less of the drug will get to your stomach. Whn swim has it crushed up as good as possible she then takes a mouthful of water or tea or something and holds swishes it around gently to get it anything stuck in teeth out and then she swallows it and voila you have an IR pill. it took a little work but it gives the same effect to me as the same dosage in IR when done this way.

[mattprice]

The best method for ingesting Opana ERs is snorting. When swim gets opana ers, he takes the coating off, crushes the pill with a pill grinder, puts a bill over it and scrapes a card over the bill, runs through chopping the pill real quick, then snorts it. Swim has found this to be the best way for using Opana ERs.

[nleksan]

SWIM was recently prescribed Opana ER 20mg 2x/day for what appears to be Degenerative Joint Disease that is affecting his spinal joints and causing severe (8/10 baseline, 10/10 "breakthrough") pain, both musculoskeletal and neuropathic. He was switched to this after being on OxyContin 20mg 3x/day for one month. Probably the fastest anyone has ever been legitimately Rx'd Opana, lol. However, because of the nature of the disease (it is not a 100% definitive diagnosis), which is chronic and progressive, he is now seeing an excellent Interventional Pain Specialist instead of the Physiologist he was seeing prior (the Physiologist Rx'd the OC, the PM Doc Rx'd the Opana).

The only good way to get "the most" out of the Opana ER's is to snort them 1-2 hours AFTER eating a high-fat meal (at least 60grams/fat). This increases the BA of oral/insufflated Opana by 15-45%. That means, potentially, a 10mg dose could result in peak plasma concentrations equal to a 15mg dose taken without a high lipid count in the blood. Pretty awesome. SWIM can say from first-hand experience that this works.

In his opinion, one (1) 40mg Opana ER snorted is equipotent to about 120mg OxyContin snorted (1.5 80mg Pills, brand-name). If the same 40mg Opana ER is snorted 90 minutes after a high-fat meal, it is equipotent to around 160-190mg of OxyContin (2-2.4 80mg Pills, brand-name). This is a significant difference, enough that a dose that would normally make you feel good and warm but still awake and alert, could have you nodding out pretty hard.

Although, for obvious reasons, one cannot increase the BA of intravenous administration, SWIM has noted a definite increase in percieved strength of IV Opana IR when administered 30-90 minutes after a high-lipid meal. 10mg IV after a fatty meal feels similar to 12-13mg of Opana IV without the fatty meal. SWIM assumes that because Oxymorphone is lipid-soluble and uses this to its advantage to pass through the BBB faster and harder than most any other opiate, increasing the lipid-content of the blood would mean that there is more lipids for the oxymorphone to "attach" to and "catch a ride" through the BBB on. This would explain the increase in percieved strength, although much more research would have to be done to say anything for sure.

[Be]

Originally Posted by mattprice

The best method for ingesting Opana ERs is snorting. When swim gets opana ers, he takes the coating off, crushes the pill with a pill grinder, puts a bill over it and scrapes a card over the bill, runs through chopping the pill real quick, then snorts it. Swim has found this to be the best way for using Opana ERs.

Swim doesn't snort she has terrible sinus problems and gets a sinus infection everytime. For the swimmers that can swim supposes its a decent method.

Be added 2 Minutes and 49 Seconds later...

Originally Posted by nleksan

SWIM was recently prescribed Opana ER 20mg 2x/day for what appears to be Degenerative Joint Disease that is affecting his spinal joints and causing severe (8/10 baseline, 10/10 "breakthrough") pain, both musculoskeletal and neuropathic. He was switched to this after being on OxyContin 20mg 3x/day for one month. Probably the fastest anyone has ever been legitimately Rx'd Opana, lol. However, because of the nature of the disease (it is not a 100% definitive diagnosis), which is chronic and progressive, he is now seeing an excellent Interventional Pain Specialist instead of the Physiologist he was seeing prior (the Physiologist Rx'd the OC, the PM Doc Rx'd the Opana).

The only good way to get "the most" out of the Opana ER's is to snort them 1-2 hours AFTER eating a high-fat meal (at least 60grams/fat). This increases the BA of oral/insufflated Opana by 15-45%. That means, potentially, a 10mg dose could result in peak plasma concentrations equal to a 15mg dose taken without a high lipid count in the blood. Pretty awesome. SWIM can say from first-hand experience that this works.

In his opinion, one (1) 40mg Opana ER snorted is equipotent to about 120mg OxyContin snorted (1.5 80mg Pills, brand-name). If the same 40mg Opana ER is snorted 90 minutes after a high-fat meal, it is equipotent to around 160-190mg of OxyContin (2-2.4 80mg Pills, brand-name). This is a significant difference, enough that a dose that would normally make you feel good and warm but still awake and alert, could have you nodding out pretty hard.

Although, for obvious reasons, one cannot increase the BA of intravenous administration, SWIM has noted a definite increase in percieved strength of IV Opana IR when administered 30-90 minutes after a high-lipid meal. 10mg IV after a fatty meal feels similar to 12-13mg of Opana IV without the fatty meal. SWIM assumes that because Oxymorphone is lipid-soluble and uses this to its advantage to pass through the BBB faster and harder than most any other opiate, increasing the lipid-content of the blood would mean that there is more lipids for the oxymorphone to "attach" to and "catch a ride" through the BBB on. This would explain the increase in percieved strength, although much more research would have to be done to say anything for sure.

Swim thanks swimmer for the advice but swim shudders at the thought of a high fat meal Also swim cannot snort because of the above mentioned sinus problems. Swim thanks swimmer again for the suggestion though.

[Herbal Healer 019]

well since only 10% is absorbed orally as was stated by som1 SWIy should try a different route of administration. Rectal administration is the best route of administration other than IV (obviously not in this case due to gelling) in terms of bioavailability and will insure that SWIy gets 90-100% of the drug into the blood as opposed to 10% if taken orally. Take half the dose SWIy would normally take when administering the dose rectally.

[Patrick from Katy]

I've had 2 spine surgeries, and have lost permanent use of my right leg due to nerve damage from the first surgeon and surgeries. They had me on Norco(2 of the 10/325 every 3 to 6 hours), but in one day I was taking about 12-16 pills.

On Tuesday, I went to my doctor and he put me on Opana ER 20MG. I had done these on the street, but I've never gotten anything higher than a 20MG. I thought they only went up to 30MG's to be honest.

Can anyone answer the following questions:

1.) How high do the MG's go up to?
2.) In comparison to Oxy-Contin, do you prefer Opana over Oxy-Contin or vice versa and why?
3.) If you were to suck on the Opana pill, like you do a Oxy-Contin to get the time release coating off, would it work the same? Or does it start gelling up?


I've just been crushing them really fine and snorting it with the shell in there most of the time, only because I can get it to such a fine powder, but sometimes the shell gets stuck. I'm trying to find a better way to get rid of the Extended Release coating without losing a lot of the pill or ruining it all together.

Thanks for any/all answers or advice!


Patrick

[award11]

From a pain relief perspective, SWIM prefers the Opana. SWIM has never seen anything higher than a 30 mg but there may be. SWIM always wet the outer coating and wiped it off with a cloth. He would then take a razor blade and chop it up into a really fine powder. Because of the low bioavailablility of Opana, SWIM never got much out of them chewing them up but when he snorted them he got the best pain relief he had ever had. As with all opiates, one must be careful with Opana, it can sneak up on you. There is a fine line between "need a little more" and "uh oh I took too much..."

Originally Posted by Patrick from Katy

I've had 2 spine surgeries, and have lost permanent use of my right leg due to nerve damage from the first surgeon and surgeries. They had me on Norco(2 of the 10/325 every 3 to 6 hours), but in one day I was taking about 12-16 pills.

On Tuesday, I went to my doctor and he put me on Opana ER 20MG. I had done these on the street, but I've never gotten anything higher than a 20MG. I thought they only went up to 30MG's to be honest.

Can anyone answer the following questions:

1.) How high do the MG's go up to?
2.) In comparison to Oxy-Contin, do you prefer Opana over Oxy-Contin or vice versa and why?
3.) If you were to suck on the Opana pill, like you do a Oxy-Contin to get the time release coating off, would it work the same? Or does it start gelling up?


I've just been crushing them really fine and snorting it with the shell in there most of the time, only because I can get it to such a fine powder, but sometimes the shell gets stuck. I'm trying to find a better way to get rid of the Extended Release coating without losing a lot of the pill or ruining it all together.

Thanks for any/all answers or advice!


Patrick

[Patrick from Katy]

Originally Posted by award11

From a pain relief perspective, SWIM prefers the Opana. SWIM has never seen anything higher than a 30 mg but there may be. SWIM always wet the outer coating and wiped it off with a cloth. He would then take a razor blade and chop it up into a really fine powder. Because of the low bioavailablility of Opana, SWIM never got much out of them chewing them up but when he snorted them he got the best pain relief he had ever had. As with all opiates, one must be careful with Opana, it can sneak up on you. There is a fine line between "need a little more" and "uh oh I took too much..."

Thanks man. The only time I really snort it is when I wake up in the morning. I just swallow the 2 dosing at night. I just need it to hit fast when I wake up because of my back.

I found that they make up to 40MG's of Opana and that it's about the equivalent to 120MG Oxy Contin.

[samuraigecko]

Originally Posted by Patrick from Katy

SWIM found that they make up to 40MG's of Opana and that it's about the equivalent to 120MG Oxy Contin.

Depending on the route of administration.

Peace

[Patrick from Katy]

Originally Posted by samuraigecko

Depending on the route of administration.

Peace

Explain that a little more in depth, if you wouldn't mind...

You talking about just swallowing compared to snorting right?

[samuraigecko]

Thats right, PO oxycodone has a higher BioAv than hydro. Oxycodone being over 80% while Oxymorphone is around 10%. (PO dosage)

However, non PO differs with Oxycodone only being from 2-3 times stronger depending on metabolism and Oxymorphone being 6-8 times stronger depending on the same.

Peace.

[3dfunk]

Swim chewed/sucked on a couple the other night and woke up the next day with a sore throat. Everything swim eats seems to have a spicey taste and swims tongue has this funky "film" all over it and is really sensitive. Not sure if there's a corelation but it sure seems ironic.

[quality2009]

SWIM has just been prescribed Opana ER 10mg. and it does nothing for swim. Swim is actually upset because Swim has CP so badly that it is difficult to function with any quality of life. SWIM read a few places online that say if it is crushed, snorted or chewed it can lead to death, so it scared the daylights out of swim. Swim also takes hydracodone 10mg but the opana is supposed to help cut back on those but it seems swim is needing to take more since prescribed the Opana ER. Does anyone have any suggestions? Would swim get better results by snorting or chewing? do they just say the "death" word to scare people? Swim would appreciate any feedback. Swim is new to this site so bare with swim, still learning the proper way to post. swim really is a happy person and full of life so swim doesnt like to whine, but lately just having a tough time.

[Daytona71]

Originally Posted by MEKONE

In SWIMS oppinion the ER's are not as good as th IR's.As stated above they turn to jell and thats to prevent IVing.However SWIM has sucked on a few and then chewed them up with decent results.But as stated before the IR's are much better than the ER's in SWIMS oppinion.

Not much info out about IR's. SWIM gets 12/day, 10mgs. and even IV'd they are not as good as hydromorphone. any special prep needed?