Dose - Virola Theiodora Resin Dosage and 5-MeO-DMT content

[69Ron]

For quite some time SWIM has been attempting to extract 5-MeO-DMT from virola bark with very little success. Apparently, the resin of nearly all the bark he’s obtained was scraped out prior to the bark being put on the market. This is commonplace.

You can tell if the bark has had its resin removed, because the resin is a dark glossy material. When its dry, its hard and very shinny. It looks nothing like bark or wood, it almost looks like a coating of thick shiny lacquer on the inside of the bark.

Anyhow, I asked around and got information from another SWIM who directed SWIM to try out Virola theiodora resin. There are a few vendors that carry this product. SWIM purchased some. It is dark brown, hard, and very glossy. It almost looks like shiny dark reddish brown sand.

SWIM bioassayed it for activity. Hearing that it contained about 10% alkalods, SWIM started at a low dose.

He first tried 20 mg sublingually, which should contain about 2 mg of alkaloids (if it truly has a 10% alkaloid content), most of which are reported to be 5-MeO-DMT. Nothing at all was felt. He then tried the same dose by freebasing the resin with an equal amount of calcium hydroxide. Still no effects.

Next he tried 40 mg sublingually. Still no effects.

Finially he tried 80 mg sublingually and noticed something. He wasn’t sure if it was placebo or not. So he tried a larger dose.

SWIM then tried 120 mg sublingually. On the way home from work he put it under his tongue and held it there without swallowing. After about 10 minutes he swallowed the grainy resin, parked at the local electronics store and walked in. He figured this was a perfect place to test its effects. After just a few more minutes he started feeling pleasant euphoric bodily sensations typical of 5-MeO-DMT fumarate. He walked around the TV section of the store and noticed how lifelike the images in the TVs were, again, an effect very typical of 5-MeO-DMT. Also, the underside of his tongue was tingling, another effect typical of 5-MeO-DMT fumarate (the freebase form burns the tongue and then numbs it slightly; the salt forms tingle the tongue and sort of numb it slightly). After about 20 minutes the effects started to peak and were very noticeable. Everything in the store looked so lifelike. All the pictures on all the DVDs were almost moving. The effects were definitely not placebo. As he walked around the store he could feel all the emotions from all the people around him. There was an intense feeling of awareness and euphoria. His body felt really nice and tingly. After about 45 minutes the effects were gone. This was roughly equivalent to a 3 mg sublingual dose of 5-MeO-DMT fumarate.

Judging by the potency and pharmacokinetics of the effects, the resin doesn’t contain freebase 5-MeO-DMT, but rather it contains a salt form of 5-MeO-DMT in the range of about 2.5% per dried gram. We can tell its present as a salt because the freebase form taken sublingually peaks faster (after 10-15 minutes) and burns the tongue a lot, while the salt forms peak slower (after 20-25 minutes) and don’t burn the tongue. Also, the salt forms are more euphoric, while the freebase form is more psychedelic. So judging by these characterizes it must be present in salt form.

It’s possible the resin contains more alkaloids other than the estimated 2.5% 5-MeO-DMT, as there could be other alkaloids present that are inactive or poorly active sublingually such as DMT. In SWIM’s sublingual tests, he only detected the effects of 5-MeO-DMT. It wasn’t colored with any other effects from any other alkaloids. But even if there was as much as 10% DMT present in addition to the estimated 2.5% 5-MeO-DMT, the DMT would have no effects sublingually at the doses tested. So the tests only show an estimated 2.5% 5-MeO-DMT content in the resin. For DMT to be active, doses of 100 mg or more of pure DMT would be needed, so at 10% alkaloids, you would need 1000 mg of resin for any of the DMT to be effective. However, judging by these tests, at 2.5% 5-MeO-DMT, a dose of 1000 mg of resin would contain 25 mg of 5-MeO-DMT as a salt, which is a very strong dose, which most people would not be able to handle, and which would completely overpower the effects of the DMT, so you wouldn’t feel anything from the DMT even if it was active. For SWIM 10 mg is a whopping dose of 5-MeO-DMT.

SWIM never tried smoking it. It will not be very effective if smoked because the 5-MeO-DMT is in salt form. It should be freebased before attempting to smoke it.

SWIM tried using it with lime (calcium hydroxide) at a ratio of 4:1 of resin to calcium hydroxide. This was placed under his tongue. It burned quite a lot, and the effect felt were that of freebase 5-MeO-DMT. So it can be freebased right in the mouth. When taken this way it peaks in 10-15 minutes instead of 20-25 minutes and hits you a little harder.

The resin is many times higher in 5-MeO-DMT than diplopterys cabrerana leaves, which usually have about 0.15 % 5-MeO-DMT.

Diplopterys cabrerana costs about $20 for 100 grams from some vendors. At about 0.15% 5-MeO-DMT, that’s a total of 150 mg 5-MeO-DMT for $20 ($0.13 per mg 5-MeO-DMT).

Virola theiodora resin costs about $25 for 10 grams. At about 2.5% 5-MeO-DMT, that’s about 250 mg 5-MeO-DMT for $25 ($0.10 per mg 5-MeO-DMT). That’s an excellent price. Considering it can be used as is without any processing, its much more convenient that Diplopterys cabrerana is.

Note that when taken as snuff, it should be ground to a powdery consistency, and it should be mixed with lime (calcium hydroxide). A ratio of 4:1 of resin to lime is good. If lime isn’t used or the resin isn’t powderized, then it’s not very effective as snuff. But when taken sublingually, its only slightly more active that way, so it can be used as is with very good results.


Let’s recap:

* Pure Virola theiodora resin is active without any preparation.

* Pure Virola theiodora resin contains about 2.5% 5-MeO-DMT in water soluble salt form.

* The threshold dose for Pure Virola theiodora resin sublingually (or as snuff) is about 80 mg.

* 120 mg of pure Virola theiodora resin taken sublingually (or as snuff) is enough for minor LSD like psychoactive effects including slight visual distortions, euphoria, altered emotional awareness, increased awareness of surroundings. This is equivalent to about 3 mg of 5-MeO-DMT fumarate.

* Contains about 16 times as much 5-MeO-DMT as Diplopterys cabrerana.

* It’s the cheapest source of 5-MeO-DMT at about $0.10 per mg of 5-MeO-DMT (as the natural form salt). We’re talking about $0.30 for 1 mild dose, $0.60 for 1 moderate dose, $1.20 for 1 strong dose.

Reputation Comments on this post:

	very informative
	extensively detailed research into the applications of virola bark. bookmarked.

[endlessnes]

you should save all this information you constantly post in one file and compile a book with all of SWIY´s tests, bioassays and chemical information. nice one, once again

[0utrider]

swim read that by heating the bark the resin may come out, even if not much left, is that true?

[69Ron]

That's a good question, but SWIM attempted to extract 5-MeO-DMT from the bark many times using many different methods. Even a Soxhlet was only able to extract traces of 5-MeO-DMT from the bark.

I doubt much 5-MeO-DMT is left in the bark because the natives scrape out the resin and sell that for use as snuff, and then they sell the leftover bark for use in woodworking, not as a source for 5-MeO-DMT. As least, that’s what I’ve been told. I know it's the resin, not the bark that has the 5-MeO-DMT in it. Once the resin is removed, there's almost none left in the bark. From time to time you might find bark with the resin still intact. You can tell because the entire inside of the bark is very glossy, as if coated with thick shiny lacquer. Most of the bark SWIM has seen was obviously scraped clean of all the resin. You could actually see the scrape marks left from the thorough removal of all the glossy resin containing inner bark.

[chemii]

Virola is great man thanks very much ILPT will have loads of fun , again many thanks to ron69`s swim for useful info.

[ljfe]

Wow, that's amazing info Ron69!
Before SWIM buys 3g of Virola theiodora resin, he must make sure: SWIM can put 200-500mg of this stuff in his mouth for 10min then swallow the material for a powerful [pleasant] 5-MeO-DMT trip? It would start 5-10min after swallowing and when he come down?

[0utrider]

yeah SWIM also wants to know
"The threshold dose for Pure Virola theiodora resin sublingually (or as snuff) is about 80 mg."
this sublingual stuff might as well be without lime? or both with lime? the 4:1 ratio, which would be 4 ? the resin, right?

another thing: could the resin be smoked (evaporated in a dmt pipe) ?? just like it is?
for a medium trip, not threshold, what would the dose be around, of the resin?
thanks in advance

[ljfe]

Sublingual should be good without freebasing, but smoking and snorting should be a 4 (resin) to 1 (edible lime) ratio.
Vaporizing should be done after freebasing (mixing well with 20% lime)
A medium sublingual dose is probably .2g of resin or more. Smoking should be in the 100-200 range just because it hits you harder and can be unpleasant.

[0utrider]

is there a way of simply doing an extraction, just like DMT, ? and then being able to smoke it?