Combinations - Dihydrocodeine and codeine sulfate

[cuddlesthefox]

Firstly swim must apologise if this is covered in another thread but swim has looked and used the search but to no avail. If it is then just a mild profanity and the link to the thread will suffice.
Oh yes, the question.
Lets say swim had a beautifully unexpected supply of dihydrocodeine 120mg SR and some 15mg codeine sulfate.
Being quite opiate tolerant, swim thought of mixing the two orally. Would this be ok? No nasty rare side effects?
Swim already thinks it would be fine but was also wondering if one or the other could cancel each other out in some way and waste the stuff.
Anyways, any advice would be appreciated.

[RoboCodeine7610]

No, they're basically the same thing.Swim doesn't think they'd cancel each other out or anything but it might be kinda hard to calculate the dose.
Anyways, as long as u got the dosages under control then you should be fine.

[yaba]

Swim didn't have any problems with dhc IR 30mg and co-codamol 30/500.
4dhc was taken and 2 co-codamol. Swim thinks the SR are somehow better/stronger not sure why.

[photonamp]

Dilip got sick from combo of 120mg dhc and 240mg codeine. No feelings of relaxation just nausea and codeine side effects. Best to take the codeine first followed by dhc.

[jon-q]

The only negative to this idea in swims opinion is with out going to deeply into the drug chemistry(SUN MORN+swims heads a bit messed up at the moment"non drug related?") Is that both codeine and dihydrocodeine use the same enzyme(up to a certain point) to convert said drugs in to more potent drugs,As this magical enzyme CYP2D6 can only convert so much drug in any given amount of time swiy wants as much of the Dihydrocodeine to convert into Dihydromorphine as poss.Codeine may use up some of this system when it's converted to morphine.
Swim hopes this makes scense to swiy and he will check/edit if need be latter on.
Best way if swiy aint prudish mix crushed DHC with warm water(10-15mls) and small amount of sodium bicarbonate and either drink or well use swiys imagination.poop poop

[Psych0naut]

Jon-g could quite possible be right, I know for a fact that Codeine(and Dihydrocodeine very likely as well) is inactive by itself and needs to be demethylated by the liver to Morphine to be active, with the help of the CYP2D6 enzyme. The amount of Codeine(and so Dihydrocodeine probaply as well) that can be converted into Morphine by the liver is limited to around 450mg by the liver enzyme, CYP2D6. Because only a limited amount can be taken, as taking more would be useless, it would be the wisest to take only Dihydrocodeine instead, because it's more potent than codeine, so of the limited amount SWIY can take of either one of them or both, the Dihydrocodeine would give the strongest effect. Dihydrocodeine is between 100% to 200% the potency of Codeine. Have fun, and please write an experience report if possible!

[Routemaster Flash]

Originally Posted by Psych0naut

Jon-g could quite possible be right, I know for a fact that Codeine(and Dihydrocodeine very likely as well) is inactive by itself and needs to be demethylated by the liver to

Nope, everything I've read about DHC makes it out to be active in itself, unlike codeine. A certain amount of the DHC is converted into DHM, just as (some) codeine is converted into morphine, but apparently it's a pharmacologically insignificant amount. Which presumably means you could snort DHC to get the effects, if you had a pure(ish) sample of it.

[Methadrone]

this may have been answered already but, swim thinks that Dihydracodeine means double. Swim thinks that's why the dihy is put in front as it's latin for meaning twice or two or double. Swim hopes swim is right and hopes this helps with dose issues.

[Routemaster Flash]

Originally Posted by Methadrone

this may have been answered already but, swim thinks that Dihydracodeine means double. Swim thinks that's why the dihy is put in front as it's latin for meaning twice or two or double. Swim hopes swim is right and hopes this helps with dose issues.

Um, not exactly! The 'dihydro-' means it has two extra hydrogen atoms, it has nothing at all to do with strength. It's said to be about the same strength as codeine or possibly up to 1.5 times as strong...from experience, SWIM would say it's perhaps a little stronger. Certainly not twice as strong.