Drug info - Hi, this is a question regarding oxycontin plz help.

[Absu]

Hello, I have a friend thats doing research on different kinds of opioids for a thesis, the other day we were having a discussion and no one seemed to be able to help us:

First, we were under the impression because of info we have read that morphine itself and oxycontin have very very similar effects on the body, is this correct?

And if it is, that was our next point, if someone took morphine orally or oxy orally would these effects still be very similar? For example, how many mg of morphine would someone have to take to mimic the effects of an 80 mg oxycontin?

If the effects are the same medical and recreational, we were wondering why farmaceuticals use oxycodone instead of just using morphine? its lasts longer? its safer? its less addictive?
Some input on this would be very much appreciated, specially from someone who knows what hes talking about, many times we have seen people disagree on this subject, and were lost.
Thank you!

[fiveleggedrat]

Every drug is completely different, although they might have similar effects.

Chocolate and fudge are both sweet, but have different textures, origins, smells, and etc.

If you look around this forum, you will see an abundance of all types of information. Wikipedia also has a good amount of easy to read information.

[Absu]

Yea ive been looking for info like this on the web. altho i cant seem to get to an article that states how similar morphine and oxy are, I dont know about the texture and smell, but the origin of oxycodone and morphine are the same: opium.

Actually oxycodone is a synthesis of morphine, which is the same as saying, synthethic morphine if im correct: from opium u make morphine, from morphine u make codeine, from codeine u make thebaine, and from thebaine you make oxycodone. Im sure people out there could hypothethically state that in a hypothethic reality they could convert morphine into oxycodone, if someone here could plz take my question serious for just one second, cut the bs and help me out, here it goes again:

IF U WERE A HYPOTHETICAL ADDICT, AND RAN OUT OF HYPOTHETHICAL OXY, AND HAD SOME HYPOTHETHICAL MORPHINE, HOW MUCH OF IT WOULD U TAKE (ORALLY OR NASALLY) TO MIMIC THE EFFECT OF AN 80 MG OXY, IN WHAT WAYS WOULD THE EFFECT BE SIMILAR, AND IN WHAT WAYS DIFFERENT. -ALL HYPOTHETICAL FOR COLLEGE RESEARCH BTW. PLZ HELP

Reputation Comments on this post:

No need to cop a attitude,ask clearer ,specific Q.

[fiveleggedrat]

Like I said, Wikipedia is also a great source of boiled down, easy to digest info.

Actually, morphine comes directly from poppies, whereas oxycodone is a semi synthetic drug that is made from codeine. The only two big all natural opiates from the poppy plant are codeine and morphine. There are many others, like theibane (perhaps 20 or more other alkaloids) that have either few or zero effects, at least in the traditional opiate-sense.

See, this is the thing: Addicts do not use other drugs to "mimic" another drug. Every drug has, at least, slightly to radically different effects. If you notice, most people that like a certain type of drug, be it benzos, amphetamines, opiates, marijuana, that they all have a certain special type or such that they like. Some drugs don't work well or at all for some people. Therefore, all drug usage is pretty much a case-by-case thing with a user. If someone is using morphine, for example, and then run out and try other morphine related drugs, they might start preferring hydromorphone because they enjoy the effects more.

And sorry, but there is no BS here. The question you are asking "hypothetically" does not make sense from a drug user's perspective. Everyone has a different tolerance. All drug users take pretty different dosages. If Swim took what a junkie took, he'd die, simply put, because he has and keeps his tolerance low.

Poppies grow in the ground. Poppies contain what most call opium. It is a mix of alkaloids (which means substances that occur naturally) including codeine, morphine, thebaine, and many more. Scientists in labs take these alkaloids and experiment with them, making new drugs. Also, they can make fully synthetic drugs that mimic the structure of natural ones. Look up methadone, it is one of the most common fully synthetic opioids.

Dark chocolate and chocolate come from the same source, but they both have different flavors and textures, which you could compare to being different effects if chocolate was to represent a drug, metaphorically speaking. White chocolate is not from the same source, and would be equal to a synthetic. Dark chocolate would be a natural, since chocolate is naturally bitter, and milk chocolate would be semi synthetic, since the choc is made into a sweet substance.

I don't think you are going to get much more of a clear answer than that.

[Absu]

It is a pretty clear answer man thanks a lot, I understand it a lot better now.

Well then I guess the next question swim would have is, how hard is it to make oxy from morphine?

Haha man thats a funny quote u have.

[fiveleggedrat]

Thank you, It makes me happy to hear you understood it well.

I posted this in your other thread, but a mod will probably delete it for being answered elsewhere, so ill repost this info.

Oxycodone is an opioid analgesic medication synthesized from thebaine.

Opioid chem is for bona fide chem experts, really.

[Absu]

Before you answer that I think the question is pretty weak again, let me rephrase it:

Could swim make oxy from morphine without professional chemist experience? If so, is there an easy to understand thread about it swim could read?
I admire that which u state about swiy keeping their tolerance low, swim is an addict and has tried to do that with several or all drugs and has failed, only to decide abstinence as the only way to keep on living, swims sanity was never returned tho, or so they say... which reminds me, R,lyeh?.... What was I remembering? lol, thnx for ur help man.

Absu added 4 Minutes and 30 Seconds later...

Oh look you had already answered it, lol, thnx man.

Ok well.. hmm.. well as for me I have no more doubts about any of this, altho swim is desperate -not desperate maybe just really interested- to find someone with this kind of knowledge, i think swim even went to the internet for help,

[fiveleggedrat]

The Ryleh thing is an allusion to author H.P. Lovecraft's mythological city in which ancient, world consuming evil resides, to try and put it simply. Look up "cthulhu". Lovecraft is my favorite author, so it made sense.

Anywho, Oxy is not made from morphine. It is made from thebaine. I do not believe you can make morphine into oxy any way, but you can make morphine into hydromorphone, oxymorphone, etc. Perhaps you are confusing oxycodone with oxymorphone?

Yes, chemistry of this type is very complicated and expensive, far out of most people's reach.

There are a few easier to do synths, like morphine to heroin, aka diacetyl morphine.

[Absu]

Yea I know H.P. and Cthulhu and all the ancients its just been a long time since I talked about them I thought u would connect the dots since Absu was according to H.P. the sea below the seas where they are dead yet sleeping.... aaanyways, so it is not possible to make morphine-codeine-thebaine-oxycodone? whats the general difference between oxymorphone and oxycodone?

[fiveleggedrat]

It's been years since I picked up a book that was not a medical journal or a PDR or similar drug reference book. My fail on not noticing that.

I don't know if what you mentioned is possible. Opiate chemistry is not cheap. Costs thousands and thousands to have decent equipment.

As you continue to post, if you post well and earn reputation, you will be allowed access to the chemistry board, which has extensive opioid chemistry walkthroughs and synthesis, but those are really not on anyone but an actual chemist's level.

[frankz81]

alot of ppl are also allergic to morphine and codeine and not allergic to the synthetic varieties like oxy etc etc...

but if u were to substitue one for the other, 100mg morphine would prob be around 40mg oxy , but alot more of the oxy will be metabolised via oral.

[Darth-Vidar]

The most important diiference between oxy and morphine from a users persepective is oral bioavalibility. Oxy is much better of an oral medication than morphine, while most IV users perfer morphine to oxy. And, one can not be converted into the other, but either will at least get you well if not high depending on dose and route of administration.

[istayhigh42o]

Originally Posted by Darth-Vidar

The most important diiference between oxy and morphine from a users persepective is oral bioavalibility. Oxy is much better of an oral medication than morphine, while most IV users perfer morphine to oxy. And, one can not be converted into the other, but either will at least get you well if not high depending on dose and route of administration.

This is very true oxycodone may be "less" potent of a opiod but the bioavaibility is way better than morphine for oral, so the effects of taking a low dose of oxycodone (orally) would be alot more effects than taking a oral dose of morphine..
But for an IV: Morphine will kick SWIY's ass alot more than oxycodone