Pharmacology - Possible strong opioid potentiator

[RoboCodeine7610]

SWIM found this in another forum:

Nigella sativa seed has opioid action. in a laboratory the seed oil suppressed nociceptive response in the hot-plate test, tail-pinch test, acetic acid-induced writhing test and in the early phase of the formalin test in rats. the activity as blocked by narcan.

yes, nigella sativa seed oil is REVERSIBLE BY NARCAN!!! very important.

the seed oil is cross tolerant with morphine, but apparently not the other way around.

the polyphenols have some analgesic activity, but it is still poorly understood. most likely the analgesia from the polyphenols is not from activity on the opioid receptor sites. the opioid activity comes from thymoquinone.

last night I took the seed oil for the first time. ingested a bit more than a tablespoon. about 30-45 min after eating the oil, my stomach was in very minor discomfort and I was experiencing opioid effects similar to kratom, but less complex. the addition of a tea made of three lanced and partly dried poppy pod was made. a tea of three unlanced pods from the plants I grew(remember alk content will vary in poppy pod) is usually a bit short of a full nod. with the seed oil, I used a much lower dose(taking into consideration the pods were lanced and much morphine was lost to collecting opium), and achieved a round trip ticket to nodland.

all in all, THIS STUFF IS GOOD! pretty easy to find, and works wonders as an opiate augmentation. I will give more reports of my use of the seed oil as an intoxicant on its own and as augmentation for oxycontin and kratom

Links:
http://www.liebertonline.com/doi/abs...jmf.2005.8.488

http://www.saudijgastro.com/article.asp?is...06;aulast=Tariq

http://www.drugs.com/npp/kalanji.html

http://www.eprints.hec.gov.pk/1813/1/1742.htm

commonly known as Black cumin it is said to greatly potentiate the effects of opioids,Does anybody know about this?Anybody tried this before?