Drug info - Rate of LSD Decay

[Lamented_Earth]

Hi,

SWIM was wondering at what rate does d-lysergic acid diethylamide decay? During the
process of decay, does the active compound simply become inert, or can
the chemical process create new compounds with different properties? And also too, does it expire or anything like that?

[PingoTango]

From TiHKAL:

EXTENSIONS AND COMMENTARY : LSD is an unusually fragile molecule and some comments are in order as to its stability and storage. As a salt, in water, cold, and free from air and light exposure, it is stable indefinitely. There are two sensitive aspects of its structure. The position of the carboxamide attachment, the 8-position, is affected by basic, or high pH, conditions. Through a process called epimerization, this position can scramble, producing isolysergic acid diethylamide, or iso-LSD. This product is biologically inactive, and represents a loss of a proportionate amount of active product. A second and separate point of instability is the double bond that lies between this 8-position and the aromatic ring. Water or alcohol can add to this site, especially in the presence of light (sunlight with its ultraviolet energy is notoriously bad) to form a product that has been called lumi-LSD, which is totally inactive in man. Oh yes, and often overlooked, there may be only an infinitesimal amount of chlorine in treated tap water, but then there is only an infinitesimal amount of LSD in a typical LSD solution. And since chlorine will destroy LSD on contact, the dissolving of LSD in tap water is not appropriate.

The rate of decay of LSD depends on many factors - temperature, humidity and light levels all play a role in its breakdown, but it can be stored for extended periods if kept properly (suspended in alcohol or pure (not tap) water, in a dark bottle, and kept in the freezer seems to be the preferred method).

It seems that all of the compounds created as a result of the decay of LSD are inactive. Keep it safe!

[ThirdEyeFloond]

It totally depends on how it's storaged, at Hoffman's 100th birthday a couple of years ago a vial of origianal Sandoz LSD approx 50 years old was sampled, and according to the consumers it's potency hadn't diminished at all. Of course the vial had been storaged optimally. Exposing a similar vial to sunlight, oxygen and heat for a few months would probably make it inactive.

[Lamented_Earth]

SWIM appreciates the input. The reason SWIM inquired into this matter is because SWIM has had some 'stuff' stashed for a little over a year. SWIM acquired a lot of 'stuff' in hopes to initiate a sort of transmutation process with regard to Leary's concept of transhumanism/metamorphosis. The 'stuff' has been in a dark area with absolutely no exposure to the sun's light, but the temperature/humidity factor certainly weighs in. SWIM has been unable to proceed in the experimentation endeavor because of a persisting illness that is barely beginning to go away. SWIM hopes to take a dive in the deep end pretty soon...

[Lobsang]

Well yes other people have stated that the Sandoz they have accidently run into that has turned up is totally potent. And SWIM knows blotter abd geltabs can turn impotent if just thrown in a drawer and forgotton about. So it all depends on storage.

[pyroarchy]

What about several blotter sheets freshly laid, stacked on top each other? Should they be put in individual bags for sheets and then into the freezer or some other moisture free cool storage? SWIM read that gel tabs (window pane) are good for storing individual doses, since most of the LSD crystal is inside the gelatin and low amount is exposed to outside, though UV radiation might still be a problem.

[Panthers007]

UV is effectively blocked by glass and/or paper. It's not like neutrinos flowing up through the floor at night. A freezer and dark rum kept pure Sandoz just fine - tyvm - for over 15 years the last time it was sampled.

[Samadhi]

Swim was cleaning out his parents old garage freezer and found a ten strip of his old acid that had to be from at least 5 years ago, it was just as potent as he remembered. It was in an air-sealed plastic bag wrapped in tinfoil with a paper towel wrapped around the blotters.

LSD if stored properly is very long lasting surprisingly. but roomtemp and left un-kept can make your blotters turn to notters (ZING!)

[Panthers007]

Yup. It doesn't require the budget of the pentagon. No inert gas-screens and liquid hydrogen temperatures. Just cold, dry, out of light. LSD25 is quite stable with a few simple precautions.