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Old 15-08-2008, 05:20
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N-Ethyl-3-piperidyl benzilate (JB 318)

Came across this substance in Be Here Now and decided to research. Ram Dass reported something like this "The girl came into the room and asked if I would like some lemonade. I said yes. She started pouring and didn't stop. The glass overflowed and then the lemonade ran off the table, onto my pants, then to the floor. It even started moving up the walls engulfing the whole room. Then the lemonade disappeared. Then the stain on my pants, then the glass, then the girl. I had just created this world in my mind" That is roughly paraphrased. Interesting no?

So this is what wikipedia has to say:

N-Ethyl-3-piperidyl benzilate

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N-Ethyl-3-piperidyl benzilate
Systematic (IUPAC) name (1-ethylpiperidin-3-yl) 2-hydroxy-2,2-di(phenyl)acetate Identifiers CAS number 3567-12-2 ATC code ? PubChem 62504 Chemical data Formula C20H23NO3 Mol. mass 339.43 g/mol Pharmacokinetic data Bioavailability ? Metabolism ? Half life ? Excretion ? Therapeutic considerations Pregnancy cat. ?
Legal status Schedule I(US)
Routes ? N-ethyl-3-piperidyl benzilate (JB-318) is an anticholinergic drug related to the chemical warfare agent 3-Quinuclidinyl benzilate.
N-ethyl-3-piperidyl benzilate is less potent and shorter acting than 3-quinuclidyl benzilate, but like 3-QNB its effects on the central nervous system predominate over peripheral effects. It produces deliriant and hallucinogenic effects similar to those of plants such as datura and may be used recreationally at low doses, however unpleasant side effects such as dysphoria, nausea and vomiting, dizziness and extreme dry mouth tend to make abuse of these kind of drugs uncommon. Both the N-methyl and N-ethyl analogues of 3-piperidyl benzilate are however Schedule I controlled drugs.
Radiolabelled versions of this drug have been used in scientific research to map the distribution of muscarinic acetylcholine receptors in the brain, however this drug has slightly lower binding affinity than the N-methyl analogue and so is less potent and not so widely used for this application.[1]









http://en.wikipedia.org/wiki/N-Ethyl...idyl_benzilate



In Canada N-Methyl-3-piperidyl benzilate "and any salts thereof" are schedule three. Not sure if JB318 is a salt of.
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Old 15-08-2008, 05:52
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Re: N-Ethyl-3-piperidyl benzilate (JB 318)

Sounds about as fun as datura...
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