Combinations - Selegiline (deprenyl) and Speed

[advanc3d]

swim is currently taking selegiline 1.5mg/day orally
swim wonders if others had the combination before, how much amphetamine did they use with the combination.

swim knows that MAOI and stimulants is a big no no but selegiline is selective for MAOI-B and correct dosage and swim is only taking 1.5mg/day with food.

[ShawnD]

Originally Posted by advanc3d

swim knows that MAOI and stimulants is a big no no but selegiline is selective for MAOI-B and correct dosage and swim is only taking 1.5mg/day with food.

http://en.wikipedia.org/wiki/MAOI#Mode_of_action

MAO-B preferentially deaminates phenylethylamine and trace amines. Dopamine is equally deaminated by both types.

Your selective MAOI and speed are both working on dopamine. Sounds like a bad mix.

http://www.selegiline.com/

A regimen of 2 x 5 mg daily of selegiline irreversibly inhibits over 90% of MAO-B in the basal ganglia, the location of over 80% of dopamine in the human brain. This level of MAO-B inhibition leads to a 40%-70% increase in synaptic dopamine.

And there's the ballpark of how potent this stuff is.

Looks like a proceed-with-caution situation. Start with extremely low doses and don't get cocky.

[advanc3d]

how low of a dose if amphetamine, swim has never taken pure base amphetamine before.

swim also as a digital scale that can measure amounts to 0.01grams

is 100mg of amphetamine a high dose to be consumed at once orally?


swim has consumed pills for over 2 years so there might be tolerance
swim also takes nootopics everyday, consisting of Piracetam....
swim realises that piracetam further intensifys stimulants

swim will be taking lots of caution as this will be his first time having the combination of selegiline and speed. but he know that 1.5mg per day of oral selegiline is a low enough dose that shouldnt cause a problem

[Nodnarb]

is 100mg of amphetamine a high dose to be consumed at once orally?

For clarity's sake, is swiy referring to amphetamine or methamphetamine? swiy says speed in the title but amphetamine in the post. Either way, the answer to swiy's question is yes, 100mg of amphetamine or methamphetamine is a big dose. If swiy does decide to experiment with deprenyl and amphetamine/methamphetamine, be sure to cut the dose of the amphetamine significantly.

[advanc3d]

Originally Posted by Nodnarb

For clarity's sake, is swiy referring to amphetamine or methamphetamine? swiy says speed in the title but amphetamine in the post. Either way, the answer to swiy's question is yes, 100mg of amphetamine or methamphetamine is a big dose. If swiy does decide to experiment with deprenyl and amphetamine/methamphetamine, be sure to cut the dose of the amphetamine significantly.

yes uncut amphetamine (not meth)

because swim doesnt know what a low dose of amphetamine is as he use to take half a gram in a night months ago and all he would feel is slight energy and wakefulness.

advanc3d added 1 Minutes and 32 Seconds later...

in australia, amphetamine is refered to "base" and if cut with glucose its refered to as speed.

meth is refered as just simple ice or meth.
sorry for the confusion.