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DXM Dextromethorphan

 
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  #1  
Old 05-03-2005, 18:46
sony01 sony01 is offline
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dxm + mirtazapine (MAOi)

can ny1 explain this 1 for me plz.. ive used dxm a few timesand had a good time, but a few nights ago i was goin out for a meal and had 2 swigs on a bottle of robuttisin, time i sat down at my table i was completely freakin my pupils went huge.. it was like 1 huge panic attack.. the night before that i took an anti depreesant( mirtazapine)to get some sleep, im pretty sure this is why it happened...any1 ever had this???

Last edited by ThirdEyeFloond; 14-06-2009 at 16:58.
  #2  
Old 10-03-2005, 05:17
tweakerfrommars tweakerfrommars is offline
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If that antidepressant is an MAOI, then yes, there is a one hundred percent chance that's why it happened. Well, being in a public place may have potentiated the panic too.
  #3  
Old 20-03-2005, 07:31
Katiii Katiii is offline
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NEVER mix the two!!!!!!!!!! u coulda killed yerself! lucky they werent high doses. Be fucking careful if ur gonna be a goddamn pill popper. Know yer shit. Medicine is dangerous. U dont want to really fuck yerself up like that. jeez dude.....
  #4  
Old 20-03-2005, 08:32
unico_walker unico_walker is offline
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Every single DXM containing product I have ever seen has a warning right on the label about mixing with MAOIs.






  #5  
Old 25-03-2005, 17:15
sony01 sony01 is offline
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ok thanks alot. any1 know y this happens tho.?
?
  #6  
Old 30-03-2005, 13:43
ISBN ISBN is offline
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mirtazapine (Remeron) is not
an MAOI, and it isn't a conventional SSRI (some don't include in in the
same umbrella as an SSRI, while others do), which makes it a bit
trickier to find solid info on. However, this doesn't look too good...



"</font>The issue with use of Remeron is due to Remerons unique status as a
alpha 2 adrenergic antagonist. These drugs greatly increase the risks
of damage called Olney's lesions. They will not cause the problem on
their own but DXM and other dissociatives (yes cough syrup is a
dissociative) bring about Olney's lesions via a different and possibly
synergistic mechanisms.

Olney's lesions are a form of permanent brain damage in which large sections of brain cells die and waste away."



"Serotonergic drugs such as SRIs (serotonin reuptake inhibitors)
including Prozac, Paxil, Zoloft, Luvox, Celexa, Serzone, and Remeron
have the potential to cause serotonin syndrome when combined with
dextromethorphan. Serotonin syndrome is a serious condition that can
result in death. It is usualy caused by increased serotonin
stimulation"



Do not continue to use DXM recreationally.


  #7  
Old 20-07-2005, 09:37
skitz0frantic skitz0frantic is offline
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NEVER MIX WITH ANTIDEPRESSANT....BIG RISK!!!! IVE DONE IT AND ALSO HAD A FREAK OUT.
  #8  
Old 09-02-2010, 17:03
waiting281 waiting281 is offline
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Re: dxm + mirtazapine (MAOi)

Nice info ISBN, think I'll go delete the thread I posted on this

do you think that remeron and DXM would have a greater chance to cause olney's lesions than any other antidepressant would in this case?

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antidepressants and dxm, drugs-forum, dxm, dxm and maoi, dxm and mirtazapine, maoi, mirtazapine, remeron, ssri

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