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Old 15-06-2008, 01:25
neuropharmacatalyst neuropharmacatalyst is offline
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Propylhexedrine and Bupropion

I've been looking everywhere for experiences with using Propylhexedrine and Bupropion together. The only thing I could find was a random post in another thread where someone said that they take the combination regularly and a lonely experience report on erowid.

Here's what I have anyway..

SWIM was prescribed 150mg Bupropion for reasons of smoking cessation and while on this dose of 150mg x 2 daily, SWIM decided to take Propylhexedrine. SWIM has now done this a multitude of times and the results are outstanding.

SWIM notices that Bupropion literally turns Propylhexedrine into another, longer acting, euphoria producing amphetamine monster.

Not sure why this is, from what SWIM knows Bupropion blocks the re-uptake of dopamine and slightly acts the same on nor-adrenaline sites. Bupropion also has quite a significant half-life, so perhaps this half-life plays a role in almost doubling the length of amp high Propylhexedrine gives?


Anyone have any thoughts about this? Ideas on the mechanism of action for these two substances combined? I'm really interested to see what SWIYs think of this.
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