Health - Human testing with a untested RC?

[fnord]

Grandma had a dream that she will soon be testing a compound that has no known human use,she understands that there will be risks invovled and wishes to minimise them. any ideas and suggestion would be great. have it from one of the leading experts that the estimated dose is 2-6mg but the largest human test ive heard of is 1.5-2mg Grandma was going to start with .5 to test for any interactions she might have,then in the next day or 2 try 1.5mgs then 2.0 5 days later then 2.5 5 more days later. What problems should be looked for? when should grandma stop increasing the dose? What ranges of BP/pulse would indicate a potential problem? The compound in question is ¨luciginol¨. Any and all advice would be nice she has noticed alot of people saying to be carefull with this one,is there some sort of red flag in it chemical structure? or is this an all around warning for untested substances?

http://www.drugs-forum.com/forum/showthread.php?t=56640

[RaverHippie]

The only thing that comes to mind would be perhaps waiting longer between doses to allow a better chance of returning to normality between trips.

[illuminati boy]

Originally Posted by fnord

Grandma had a dream that she will soon be testing a compound that has no known human use,she understands that there will be risks invovled and wishes to minimise them.

Reading about Shulgin's protocols for testing substances would probably be a good starting point. He was extremely conservative at times when working up to an active dose. He was especially conservative when starting with a new class of compounds. In all honesty if there is no human data whatsoever it may not be out of the question to start sub microgram. Even if some Grandma had secondhand reports about rough dosing range, there is no way to know that they wouldn't have an idiosyncratic reaction (allergy, extreme sensitivity, etc.).

Originally Posted by fnord

...have it from one of the leading experts that the estimated dose is 2-6mg but the largest human test ive heard of is 1.5-2mg.

Grandmas should probably consider all data on extremely novel compounds to be suspect unless directly verified. Grandmas should also have the requisite knowledge(s) needed to engage in such an undertaking. At a minimum besides reading Shulgin's account prospective Grandmas should check out HERE and go through a risk/benefit analysis of such potential Grandmotherly endeavors.

IB

PS: Be EXTREMELY skeptical of all advice including even this.

Reputation Comments on this post:

good advice