Concerta tolerance...

[Mortis]

I haven't used ritalin/concerta for few years and just got a script.
Due to my stupidity i started abusing them, first chewing one at time 2-3 days ago. today i chewed 4 54mg tabs... been eating them around 15 in the course of 2-3days... Now i wonder if just eating one after tomorrow(not eating any then) would work at all ?

i kinda need them to studying, but they don't work as well as ritalins as the stuff is released so slowly...

[no-go]

So... swiy is worried about tolerance after 3 days of "abuse"? Short answer: No, a single Concerta will not work on day 5 after hiatus on day 4. Unless swiy slept THE ENTIRE FREAKIN DAY. And ate good protein-rich, low-fat food. But have hope. Long answer: This is not an irreversible tolerance crisis. Because, "abuse"? Really? Let's see...

Chewing is an off-label route of administration, but swim seriously doubts chewing Concerta effectively defeats the time-release... "misuse" is more appropriate than "abuse"...

O/c Concerta provides an immediate release dose along with its ER dose. Supposedly studies confirm one 18mg Concerta achieves about the same peak plasma concentration in 10 hours as 3x5mg IR taken four hours apart, or in 6 hours as 2x5mg IR taken four hours apart, which practically is only effective enough for a 5-year old.

As an educated guess, 1x54mg Concerta is about 45mg IR by peak plasma levels if 15mg is taken every four hours. That's like taking 2.3x20mg Ritalins in 12 hours. The third dose is given after eight hours. That one 54mg Concerta means only 30mg of IR through a 9-5 work day! Or a 8-4 college day. With four hours of dwindling study utility after that. No wonder swiy took more. If one NEEDS MPH, is that dose realistically effective? Would any long-term MPH user here take 3/4 of a 20mg IR pill orally and be good for four hours? Cos that's about the best 54mg Concerta will do. And that is bullsh*t. Besides, plasma concentrations do not accurately measure the desired subjective effects of the medication. Get off Concerta, get on the IR!

So swiy took 15 in 2-3 days? The average is 5 a day, or 270mg/day! If Concerta were at all as effective as IR, that's like taking 13.5x20mg/day. Swim hopes that number frightens swiy not to repeat that experiment... But with a half-life of max. 4 hours, if the Concerta were taken every 2 hours, that works out to 2.25x20mg max each 2hr from hrs 4-8 to 10. With that much, MPH probably lost its effectiveness after hr 6 which amounts to over 135mg MPH IR and the rest went to waste. How could swiy not be burned out and miserable by then? The rest of the day must have given sporadic 15 minute bursts? Doubtless sleep came easy?

2 days of good rest and healthy protein-rich foods (fish, chicken), then 2x Concertas swallowed at once on an empty stomach would be effective for studying... But Swiy should get off Concerta asap. SR or IR are better. Since swiy has a script, that'd be easy, and the reason is economic so it's legitimate; post or PM if interested on how this is to be accomplished. Yea, swiy messed up, but given it was Concerta, it's totally understandable.