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Changes in alcohol craving and consumption by phase of menstrual cycle in alcohol dependent women (2006)

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Journal of Substance Use October 2006; 11(5): 323–332

E. E. EPSTEIN
, K. C. RHINES, S. COOK, B. ZDEP-MATTOCKS,N. K. JENSEN, & B. S. MCCRADY
The current study examines the menstrual cycle–alcohol relationship during 6 months of weekly
outpatient sessions as part of a larger treatment outcome study for alcohol-dependent females.
Twelve premenopausal women in the clinical trial who were menstruating regularly and not on oral
contraceptives kept a daily log of menstruation days, alcohol consumption and cravings. Three
menstrual cycle phases were defined: menses, premenstrual, and ‘‘other.’’ Within subjects repeated measures analyses on the subsample of 12 women showed that, despite a lower average number of cravings, drinking frequency was higher in the premenstruum than the ‘‘other’’ phase in the first 3 months of treatment. In addition, according to a self-report item on a measure given to 96 women in the larger study, 48 (69%) women under the age of 50 endorsed the premenstrual phase of the menstrual cycle as a drinking cue. Of these 48, 44% considered it a major drinking cue. These
preliminary data support the value of continuing to investigate the relationship between phases of the
menstrual cycle and alcohol consumption among female alcoholics



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