swim cant get high after dosing on phenibut

[allyourbase]

swim used phenibut recently, and smoked all day the next day, using twice the normal amount, to no effect. is this normal?

[lulz]

Like alcohol and benzos, phenibut acts on GABA receptors. But alcohol and benzos mainly affect GABA-A receptors, while phenibut affects GABA-B receptors.

Another GABA-B agonist, baclofen, apparently has some kind of shared neural activity with THC -

http://cat.inist.fr/?aModele=afficheN&cpsidt=1834418
http://www.ncbi.nlm.nih.gov/pubmed/15910802

So whether a cross tolerance between phenibut and weed is common or not, at least it seems possible?

[Greenport]

oh no, a drug that causes THC to have no effect you say?

...what if they were to start giving this to people who got caught with marijuana? Oh just think of the horror!

SwiM would still smoke anyways tho

[MountainDeW]

Wow is SWIY serious? SWIM has just finished off about 30g of a 100g container. This Phenibut is in powder form and can be taken in increments of 1-2 grams for effect. 2 grams for an initial dose will definitely have a powerful effect. Phenibut works but modulating GABA. Also SWIM has had a great experience with a small Phenibut dose and a cannabis cake. This was probably SWIM's favorite experience with Phenibut.

Recommendations:
-Powder not pills
-1-2 gram initial dose
-Experiment with synergistic drugs (cannabis, alcohol, piracetam, caffeine)
-Find a sexual partner for AWESOME SEX!
-Avoid pitfalls ("Oh this isn't working I'm going to double dose")
-Take breaks, do not take for more that 3 days in a row.

Positive Effects:
-Euphoria, ED treatment, relaxation, social lubricant, "booster drug"

Negative Effects:
-Rebound (anxiety, high blood pressure, depression, insomnia).
-Overdose (nausea, dizzyness, clouded thinking, over-sexuality, loss of inhibition).
-Tolerance

The side effects are similar to benzodiazepine's. The positive effects are even better, just keep it in your pants

[malsat]

OP, did you mean you couldn't get high on cannabis or G?

SWIM has had experience with chronic phenibut dosing and found it ramped up tolerance/dependence on G extremely rapidly - far more quickly than GBL utself does. Going from a light GBL tolerance, through 2 weeks of phenibut usage to exceptionally severe WD's from GBL after 2 weeks of GBL use (straight after the phenibut use).

I would recommend against chronic dosing of phenibut and use of GBL directly after such phenibut use.

Reputation Comments on this post:

this is definitly something i also have experienced, thanks for posting