Mylan fentanyl patches- a different method?

[paranoid_android]

SwiPA would first like to say that he checked many threads to see if this was covered. He couldn't find it but that doesn't really mean anything. Now, onto the tek.

It's been stated that the fentanyl in mylan patches can be extracted with solvents, even regular 80 proof spirits. It's also known that fentanyl is absorbed best transdermally (and perhaps buccally).

SwiPA surmises that a patch could be soaked in a small amount of 91% isopropanol. The solution could then be applied to the skin with a dropper for minimal waste versus most other routes of administration.

If SwiPA can get ahold of a used mylan patch tomorrow he will try this with part of it and report back. In the meantime, what do yall swimmers think?

[OhCasey]

Sounds interesting, I cant wait to hear your results.

[lightworker]

SWIM has these Mylan 75 Patches. The ones without the Gel. Just thin and Flat. SWIM wore one for 3 day... didnt feel anything. Put on another one about 1 Pm yesterday. Still doesnt feel anything now. SWIM has one patch left. And Wants to know if cutting it into strips and putting it in between my cheeks and gums would work. Or this alcohol method, because SWIM has 91% iso Alc...

SWIM has an opiate tolerance of about 100 - 140 mg oxy.
All help appreciated.

[Matt The Funk]

Originally Posted by lightworker

SWIM has these Mylan 75 Patches. The ones without the Gel. Just thin and Flat. SWIM wore one for 3 day... didnt feel anything. Put on another one about 1 Pm yesterday. Still doesnt feel anything now. SWIM has one patch left. And Wants to know if cutting it into strips and putting it in between my cheeks and gums would work. Or this alcohol method, because SWIM has 91% iso Alc...

SWIM has an opiate tolerance of about 100 - 140 mg oxy.
All help appreciated.

Wearing the patches was a mistake. SWIM thinks cutting them into 1/16ths and figuring out your dosage from there (SWIM figures it to be about 20mg of morphine).

[lightworker]

Originally Posted by Matt The Funk

Wearing the patches was a mistake. SWIM thinks cutting them into 1/16ths and figuring out your dosage from there (SWIM figures it to be about 20mg of morphine).

yeah LW shouldnt of put the patches on, LW read around and found out that the Mylons are only good for under tongue or gums and cheeks. So LW cut them up into 12ths. And sucked on 2, LW feels alright, pretty relaxed. LW doesn't know if its from the herb LW smoked earlier, but probley not. LW will try 2 more under the tongue at 6. When SWIY says 20mg of morphine in each little square. LW cut his into 12 pieces. LW is sad he wasted 2 other patches... Oh well. Any Way to smoke these? Vaporize? Appreciate it

[Matt The Funk]

Oh they're 75mcg....SWIM didn't notice. Anyways it might be a little closer to 15mg when cut into 1/16ths. Since they were cut into 1/12th's....SWIM is guessing SWIY is getting about 45mg equivalent. Tolerance builds up to these VERY fast...so if SWIY isn't an opiate addict (even if one is) SWIM highly discourages to continue using them if there is only 1 patch left, and saving it for the weekend or something. There is no way to smoke or vape these particular types of patch that SWIM knows of. Be careful with em too, SWIM ended up taking about a whole patch (doesn't remember but is somewhere in another fentanyl thread) along with some darvocet and adderall XR, and of course dank herbals, and went to the opiod nod-hallucination land. Also just to give SWIY a little knowledge on his tolerance, it was a lot lower at the time (2 months clean when the hallucinations happened), he likes to take about 5/12ths or so over the course of 1 1/2 hours. But that's just how he use to do it. His tolerance to something more accurate in dosage would be....probably 100-150mg of hydrocodone for that same feeling (although hydrocodone effects him a lot stronger than other opiods and is his favorite). Hope this post helps.

[OhCasey]

If you do wear them swim suggests hitting them with a blow dryer or putting a heating pad on them. Just be careful as it will release alot more of the ingredients alot faster and swiy will drain swiyour patch in 1-2 days. Also this works for both the mylans and gel ones but seems to work better with the mylans.

[Orchid_Suspiria]

Just take a hot shower or bath.This is a foolproof method to get fentanyl patches to work much quicker.Swiy shouldn't be eating fentanyl.Eating plastic laced with fentanyl and other chemicals just can't be good for a person.

[Psych0naut]

SWIM has had Durogesic patches in the past, which don't contain gel either. He always cut the righ dose off of a patch with his scissors, and stuck it underneath his tongue, and chewed on it 5 minutes later, to release all the Fentanyl from the plastic matrix. It's really important to keep the bit of patch in ones mouth for 15 minutes or so, of which 10 minutes one has to be chewing on it, to release all the Fentanyl.

Extracting the Fentanyl will work well too. Around 98% of the Fentanyl in a Durogesic patch can be extracted by letting it soak in strong liquor overnight. This has been tested with quantative analysis, and the 98% percent yield is a true percentage. Janssen-Cilag's rivals claimed that Durogesic had the same abuse-factor as gel-based patches, so they proved it by doing an extraction on them with easilly obtainable chems, in this case, strong drinking alcohol, namely wodka and rum. SWIM has explained how to perform this extraction to yield a safe solution in several other threads, so UTSE to find it.

[Matt The Funk]

Originally Posted by Orchid_Suspiria

Just take a hot shower or bath.This is a foolproof method to get fentanyl patches to work much quicker.Swiy shouldn't be eating fentanyl.Eating plastic laced with fentanyl and other chemicals just can't be good for a person.

You never actually eat the plastic....

[lightworker]

MYLAN sucks pretty bad. SWIM sucked on them, chewed them, everything. Nothing special... LW much rather buy some herb and chill. LW will wait for the other patches with the gel inside... Otherwise MYLANs aren't worth it in LW's opinion. Unless LW was getting them fairly cheaper. Thank SWIYou for all the help.

[OhCasey]

dont swallow your spit

[Matt The Funk]

Originally Posted by OhCasey

dont swallow your spit

Yeah.

[paranoid_android]

SwiPA has been thinking about a slight change to this method for a while, but hasn't had a chance to get a patch. It's very likely SwiPA will obtain one tomorrow, and if he does then part of it will be extracted with a solvent. Now onto the tweak.

It came about when SwiPA was thinking about how runny the solution would be. It could spill or run off if not applied properly. Then he realized there is a perfect little receptacle for this sort of concoction: the belly button.

SwiPA is anxious about possibly wasting fentanyl, so if he finds buccal/sublingual routes to work very well for him, he might not risk an extraction. Still, he seems very intrigued by the possibility of "navel administration".

[OhCasey]

The thought of naval administered fentanyl makes me shiver. I guess I'm just weird about my belly button.

[paranoid_android]

SwiPA just realized that there is a penetrating agent involved in the patches. Regular isopropyl might work as such a catalyst, and it might not. Either way, yet another new addition to this popped into my head:

If a potent, homogenized solution of fentanyl was mixed consistently with benadryl (diphenhydramine) anti-itch cream, the end product could be an all-in-one "nod cream". Of course, great care would be needed to ensure a standard potency throughout the cream. If several patches were used and the cream was placed back in the benadryl tube, it would be a very discreet and portable way of getting high.

Any thoughts?

[Matt The Funk]

Originally Posted by paranoid_android

SwiPA just realized that there is a penetrating agent involved in the patches. Regular isopropyl might work as such a catalyst, and it might not. Either way, yet another new addition to this popped into my head:

If a potent, homogenized solution of fentanyl was mixed consistently with benadryl (diphenhydramine) anti-itch cream, the end product could be an all-in-one "nod cream". Of course, great care would be needed to ensure a standard potency throughout the cream. If several patches were used and the cream was placed back in the benadryl tube, it would be a very discreet and portable way of getting high.

Any thoughts?

Death.

[OhCasey]

Originally Posted by paranoid_android

SwiPA just realized that there is a penetrating agent involved in the patches. Regular isopropyl might work as such a catalyst, and it might not. Either way, yet another new addition to this popped into my head:

If a potent, homogenized solution of fentanyl was mixed consistently with benadryl (diphenhydramine) anti-itch cream, the end product could be an all-in-one "nod cream". Of course, great care would be needed to ensure a standard potency throughout the cream. If several patches were used and the cream was placed back in the benadryl tube, it would be a very discreet and portable way of getting high.

Any thoughts?

With no way to test potency or make sure the fentanyl was equally distributed it would be dangerous to make a large quanity.

[Psych0naut]

Originally Posted by paranoid_android

SwiPA just realized that there is a penetrating agent involved in the patches. Regular isopropyl might work as such a catalyst, and it might not. Either way, yet another new addition to this popped into my head:

If a potent, homogenized solution of fentanyl was mixed consistently with benadryl (diphenhydramine) anti-itch cream, the end product could be an all-in-one "nod cream". Of course, great care would be needed to ensure a standard potency throughout the cream. If several patches were used and the cream was placed back in the benadryl tube, it would be a very discreet and portable way of getting high.

Any thoughts?

Both Durogesic(gel-less patches) and Duragesic(gel patches) contain ethanol as solvent, so I assume Mylan patches contain ethanol as solvent as well. SWIM thinks there is a pretty clever mechanism in those patches, because it takes a while (around 3 hours) after putting them on one's skin before one feels the Fentanyl having effect. SWIM doesn't think that dripping extracted Fentanyl dissolved in ethanol on one's skin wouldn't neccesarily get absorbed transdermally. Remember there's a pretty clever mechanism in those patches, which causes it to take around 3 hours before one feels it taking effect. One would expect that dropping a concentrated solution of Fentanyl dissolved in a suitable solvent like ethanol on one's skin, would cause effect in 15 minutes, 30 minutes max. Certainly not 3 hours. I think the reason why it takes so long for patches to achieve a high enough serum level for one to feel the Fentanyl pretty strong, is because of the special mechanism the patches work through. They build up a reservoir of Fentanyl just under the skin, where it starts to pool up and get's larger and larger in volume untill it has spread so much that the pooled up subcutaneous reservoir of Fentanyl spreads around a vein or several veins, or some capilaries where it enters the bloodstream and get's carried to the brain. It pretty clear why it takes so long before a Fentanyl patch starts to give any noticeable effects after having it put on to the skin. The rate at which the patch gives off it's Fentanyl stay's the same, no mather what(only temperature can control this rate) The rate at which a Fentanyl patch normally gives of it's Fentanyl is relatively slow, depending on which patch one has; 12.5mg/25mg/50mg/75mg/100mg per hour. This is generally plenty enough once the reservoir underneath one's skin has pooled up well enough so that the Fentanyl get's absorbed directly from the patch on one's skin, through the subcutaneous reservoir into the bloodstream. But ofcourse at such a rate, it does take some time before enough Fentanyl has pooled up under one's sking to have reached a/some vein(s) or capilaries. Those patches might take a long while to full work after they've been applied to the skin, but they do get a wopping 92% bioavailability, which is truly massive.

But back on topic, enough explaining about how a Fentanyl patch works ... Because of the cleverly engineered mechanism those patches rely on, one would have to imitate that mechanism for the largest part, to be succesful. And it won't be easy to figure that out. I'm pretty certain that Fentanyl dissolved in ethanol won't work if dripped onto the skin. DMSO(DiMethylSulfOxide) might be a better alternative. DMSO has the unique property that it's an excellent solvent for many substances, and due to it's polarity can pass through the skin and maybe eveb into the mucles or a vein, where the substance dissolved in DMSO would reach the brain rather fast. The best place on the body to apply DMSO solution containing Fentanyl would be on one of the bulging veins at the junction of veins on the inside of the arm. Make shure, absolutely shure, that the dose isn't too high, or one could be a stiff in less than 5 minutes. Proper dosing of Fentanyl is serious business.

For extracting the patch for sublingual use, I'll refer anyone who wants to read more about it, to my post in another thread.

Reputation Comments on this post:

Good info

[lazor]

One might try an extraction by letting the mylan patch soak in a small amount of isopropyl for a minimum of 24 hrs (preferably in a small clear glass container) After a good soaking, let the liquid evaporate off completely, you should find a residue of clearish crystals at bottom of glass. What you do from there is remove the residue using the best method avalible to you. Swim did this with a 50 mylan patch and was successful. It was just an experiment just to see if this was feasable. Swim would never do this for any other reason.

[kathyp]

Very difficult to do with the ones with no gel in them.

[H3AD_TR1P]

Originally Posted by Orchid_Suspiria

Just take a hot shower or bath.This is a foolproof method to get fentanyl patches to work much quicker.Swiy shouldn't be eating fentanyl.Eating plastic laced with fentanyl and other chemicals just can't be good for a person.

haha this may be a little off beat and funny but swim likes to tan so when ever swim puts a new patch on swim goes to the tanning salon (all the time cause swim works there) and in the warmest bed for the full time definaely helps with making it work much quicker, just make sure swim doesnt nodd off while in the bed and have to awaken to a fellow employee knocking on the door "what the hell are you doing in there, sleeping!?!?"
swim says try this method if swimmers are tanorexics !

[User0]

I have found a way to extract the fentanyl from the mylan patches. The result is a smokable resin. First I must warn that the resin is VERY potent; and an accidental OD is very easy to achieve, so BE CAREFUL: First you take the patch and immerse it in a very small amount of alcohol (I used vodka in a small glass), just enough to cover it (I had a 75ug patch). Allow several hours for the fent to dissolve into the alcohol. The next step is to remove and discard the patch. Pour the liquid onto a glass plate. Place the plate in the microwave for only a few moments (do not let all the liquid evaporate). There should be a small amount of liquid left on the plate. Using a razor blade, move the remaining liquid to the center of the plate. Put the plate somewhere & let the rest evaporate. What will be left can be scraped off the plate with a razor blade. You will end up with a small amount of a resin-like substance that can be smoked on foil. A piece the size of a BB is MORE THAN ENOUGH. If you decide to do this please be very careful & have someone around to monitor you.

[trannyboy]

Okay, this is what I can offer to the discussion. I don`t know specifics of this drug but I know quite a bit about mucual and dermal absorption theory. I will give you what I know. Please keep in mind that the majority of my knowledge in this revolves around hormones but I am aware of many of the basics for this subject.

First the thinner the skin the higher the absorption. This means if you attempt to absorb something through the back/ stomach/ shoulders/ chest/ etc areas it will take longer and less will be absorbed then the neck/ behind the ears/ genitals/ armpits/ inner thigh/ elbow, etc In addition to that mucus membranes are very thin and that includes the bowels, bladder, vaginal vault, mouth, inner eye lids, genitals and nose. Bear in mind the thinner the tissue the greater the chances of irritation. The mucus membranes alone are easily damaged and rely on a complex balance to function and survive.

Wash that area, but maybe don't rinse as well. Many have noticed that if a soap residue is left on the skin after cleaning that it results in higher absorption rates both in quantity and speed. However if you have applied other topical products on the same area prior it will slow absorption rates. So the deal is wash the area, lightly rinse the area, then after use and certainly prior to secondary use wash the area properly to remove any residue of the previous product.

If you have to rub the product into the skin make sure to cover the hand that is rubbing with a latex/ vinyl/ nitrile glove or at the least some plastic wrap or a sandwhich bag to protect your hand from absorbing the product. The reason for this is the same reason you can't tattoo hands easily. The skin in the hand readily absorbs the product but will not retain it. It will be flushed out of your hand quickly as your hand sweats and breath. This is critcal to protect the dosage. In people using topical hormones we have seen a difference of half to less a quarter of the doses needed then with an unprotected hand.

In addition most topical products will enter skin at a faster and higher rate if the skin is covered with an occlusive dressing. So always use either a piece of tegaderm or plastic wrap and tape over the treated area. The reason for this is that when the skin can't breath and sweat and heat build up allowing the skin to become more permable by increasing things like pore size and the space between the cell at a cellular levels. Using an occlusive dressing (one that air and water can't pass through) will also protect other from skin to skin transmission.

Despite all factors the skin is meant to keep things out and because of that many drugs simply have too large doses to be able to get enough through the skin to be effective. Generally doses that are in mg instead of mcg can't be dosed topically without some sort of product to change the skin and make it more permable. There are chemicals which do that but they aren't the best things to be putting on the skin. Remember that skin is our protection against the world and if we damage it then we leave ourself open to all sorts of toxins. DMSO is one of those products that can do it but the risks are high not the least of which it smell awful and so will you if you use it. This is another reason to cover the skin if you must use a dermal absorption enhancer. In general doses over 10mg won't be able to use a topical route except with mucus membranes and doses of over 100- 500mg tend to be generally impossible topically.

PH is also important when trying to use a product topically. Off hand I can't remember though what PH we are looking for and the article is on an old hard drive, so I will have to edit later on this issue.

It is also a waste because with most skin the general rule is 10:1, i.e. 10mg applied equals 1mg absorbed. This dose flucuate based on other factors but even then the best you should hope for is 10:3 ratio. Mucus membranes are different and can range from 10:3 to 10:9 with the proper steps and prep. So of all the mucus membranes are the best for absorption if you get away from the possible damage to the membrane.

Despite all of this if you choose skin preps be aware and start small. Some people are unique and absorbs greater amounts then normal. I once saw a man taking topical testosterone and without using any of the above tricks he only needed a tenth of the recommended dose when most need much more then the recommended dose. When he switched to my techniques he cut that in half while maintaining the same blood levels. So start small and if you find that you are oding wash the area at least five times with dish detergant and seek immediate medical care.

trannyboy

[Sib]

Originally Posted by User0

I have found a way to extract the fentanyl from the mylan patches. The result is a smokable resin. First I must warn that the resin is VERY potent; and an accidental OD is very easy to achieve, so BE CAREFUL: First you take the patch and immerse it in a very small amount of alcohol (I used vodka in a small glass), just enough to cover it (I had a 75ug patch). Allow several hours for the fent to dissolve into the alcohol. The next step is to remove and discard the patch. Pour the liquid onto a glass plate. Place the plate in the microwave for only a few moments (do not let all the liquid evaporate). There should be a small amount of liquid left on the plate. Using a razor blade, move the remaining liquid to the center of the plate. Put the plate somewhere & let the rest evaporate. What will be left can be scraped off the plate with a razor blade. You will end up with a small amount of a resin-like substance that can be smoked on foil. A piece the size of a BB is MORE THAN ENOUGH. If you decide to do this please be very careful & have someone around to monitor you.

This is what SWIM does though a different process and SWIM uses 100 mcg patches (about 4) ethanol, baking soda and some acid, leaves SWIM with crystals that can be easily smoked in a bong, nice