New High from Adderall + Seroquel !!!

[kbsuperstar]

Apparently, SWIM has stumbled upon a new high SWIY can experience by combining seroquel and adderall (crush both pills up and mix the powder; then insufflate). It brings SWIY from a state of fatigue and sleepiness to being really sped out and hyper, back and forth and back and forth. It's quite entertaining, and a couple of SWIM's friends really like it, too.

Anyone else ever tried this? SWIM doesn't know if this is the write place for this thread, but SWIM just wanted to spread the word - this combination rocks! And it gives a whole lot more value to seroquel, which SWIM now sells with adderall.

Maybe SWIY should try it out

[fizzle]

Swim has done countless amounts of Adderall but Seroquel (quetiapine) only one time by itself. Seroquel is an anti-psychotic which really can knock you out. Swim does not see this as a good combo from a chemistry standpoint, though the main meds not to take with it seem to be downers, painkillers, anti-depressants, etc. but swim has never mixed Seroquel with anything.

[thenightwatch]

This particular combination seems as if it would be terrible for your body and mind. SWIM has not taken Quetiapine (Seroquel), nor did he previously know the mechanism of action of it, but just a quick glance at the pharmacology of Quetiapine tells SWIM that it is a Dopamine/5HT/Adrenergic receptor ANtagonist. Amphetamine is a Dopamine/Adrenergic/5HT Agonist.

SWIM hopes he does not have to point out the logic behind why this combination seems to be a bad idea (on so many levels).

Please, all you other SWIYs, I really hope you attempt to exhaust all of your other means of getting high before resorting to something like this. SWIM knows the urge to combine drugs for novel experiences is high, but sometimes its just a plain bad idea...

[OhCasey]

Originally Posted by kbsuperstar

Apparently, SWIM has stumbled upon a new high SWIY can experience by combining seroquel and adderall (crush both pills up and mix the powder; then insufflate). It brings SWIY from a state of fatigue and sleepiness to being really sped out and hyper, back and forth and back and forth. It's quite entertaining, and a couple of SWIM's friends really like it, too.

Anyone else ever tried this? SWIM doesn't know if this is the write place for this thread, but SWIM just wanted to spread the word - this combination rocks! And it gives a whole lot more value to seroquel, which SWIM now sells with adderall.

Maybe SWIY should try it out

Swiy should post a more in depth report and include dosing as this might be useful to more members. as far as the other posts in this thread im glad you guys are posting your concern as this is a harm reduction site but unless you have sources to site or have tried the combonation you might want to wait on passing judgement. I myself am not familiar with this combo but swim has a friend who takes this every night after he takes his adderall xr to help him sleep and he says its quite common for people comming down from adderall to take seroquel to help relax and reports no harmful effects from the long term mixing of the two.

[kbsuperstar]

SWIM has only tried combining 20mg Adderall XR with 25mg Seroquel, but his friends have tried 20mg Adderall XR with 50mg Seroquel.

Seroquel doesn't exhibit anti-psychotic effects at low doses (anywhere from 25mg - 125mg). Its anti-psychotic properties become more apparent at higher doses ranging from 300mg - 600mg.

SWIM recommends trying to keep the Adderall - Seroquel ratio at about 1:1, but if not, at least use more Seroquel than Adderall (since it's harder to overshoot a Seroquel dose than Adderall).

Good luck and have fun!

[BearClaw]

Swim agrees with thenightwatch, this seems like a horrible combination. The high might be unique and fun, but think of the toll it takes on swiy's body...

Swim has taken seroquel a few times and found it to be a horrible recreational drug. Since its an anti-psychotic, swim finds it a bit difficult to use this as a recreational drug and strongly cautions swimmers who do.

Please for swiy's own health, caution your use and be careful.

[Donmeka]

wen SWM thinks about this mix he thinks a better option wold be a gun to his dome. seroquel makes SWIM feel suicidal and twacky similar maybe worse to the twacky feeling he got from adderall which he didn't have an all too good experience from either.

thats why SWIM has his sweet sweet desoxyn, all the love with none of the stress of the beautiful helping world of amphetamines. (to SWIM anyway) The mild euphoria and great focus SWIM gets from it is a godsend

[OhCasey]

It really is different for every person. With that said ive never had any suicidal or "twacky" feelings from both seroquel or adderall. Does anyone know that this can take some kind of toll on your body or is this just the opinions of few.

[kbsuperstar]

Even though a lot of you all keep saying that seroquel is bad to mess with, none of you have provided any reasoning to back up your opinions.

[thenightwatch]

I'd say the responsible way to proceed would be to acquire proof that something isn't BAD to mess with first, and only then taking whatever crazy combination of drugs you want.

There is not much research out there on this combo. Just this thread is already on page three of the Google results for "seroquel adderall." There are a few hits from people that take Seroquel as a no-go pill after taking Adderall during the day, but concurrent administration is apparently unheard of. In fact, concurrent administration is something that will likely never be prescribed by a doctor, and as such, there will probably never be any medical research done on it. You will not find a giant warning sign that says "Don't mix Adderall and Seroquel!" anywhere, so asking us to produce such is pretty pointless...

[vile_audio]

seroquel basically stops all dopamine action amphetamines basically mimic dopamine


this is a bad idea

one time after a three wk long run with under 50 hrs of sleep vile took a 200mg seroquel

he stayed in bed for a week sleepin 23 hours outta the day

he could barely lift his spoon to eat cereal

fuck that i like having dopamine in my synapses at all times

[kbsuperstar]

The most common side effect of quetiapine is sedation [20] It is prescribed specifically (off-label) for this effect in patients with sleep disorders. Beginning users may feel extremely tired and 'out of it' for the first few days, sometimes longer. Quetiapine's newest indication, for bipolar depression, usually specifically calls for the entire dose to be taken before bedtime due to its sedative effects. Although quetiapine is approved by the FDA for the treatment of schizophrenia and bipolar disorder, it is frequently prescribed for off-label purposes, including insomnia and the treatment of anxiety disorders. The sedative effects may disappear after some time on the drug, or with a change of dosage, and with possibly different, non-sedative side effects emerging.

[20]
^ Jon A. Shaw, John E. Lewis, Shlomo Pascal, Rakesh K. Sharma, Rosemarie A. Rodriguez, Ramiro Guillen, Marilyn Pupo-Guillen. "A Study of Quetiapine: Efficacy and Tolerability in Psychotic Adolescents". Journal of Child and Adolescent Psychopharmacology December 1, 2001, 11(4): 415-424.

[thenightwatch]

Originally Posted by kbsuperstar

The most common side effect of quetiapine is sedation [20] It is prescribed specifically (off-label) for this effect in patients with sleep disorders. Beginning users may feel extremely tired and 'out of it' for the first few days, sometimes longer. Quetiapine's newest indication, for bipolar depression, usually specifically calls for the entire dose to be taken before bedtime due to its sedative effects. Although quetiapine is approved by the FDA for the treatment of schizophrenia and bipolar disorder, it is frequently prescribed for off-label purposes, including insomnia and the treatment of anxiety disorders. The sedative effects may disappear after some time on the drug, or with a change of dosage, and with possibly different, non-sedative side effects emerging.

[20]
^ Jon A. Shaw, John E. Lewis, Shlomo Pascal, Rakesh K. Sharma, Rosemarie A. Rodriguez, Ramiro Guillen, Marilyn Pupo-Guillen. "A Study of Quetiapine: Efficacy and Tolerability in Psychotic Adolescents". Journal of Child and Adolescent Psychopharmacology December 1, 2001, 11(4): 415-424.

What's your point?

[kbsuperstar]

The anti-psychotic properties of seroquel don't affect the user at low doses; the only effect that results from low doses ( ~125mg or less) is sedation. Ergo, don't mix with drugs that already cause sedation, and the user shouldn't be doing activities that are risky while sedated.

You can pretty much mix seroquel with anything without reason to worry. SWIM takes 100mg daily (it's prescribed to him), and he still uses drugs all the time without any bad reaction due to the seroquel.

Personally, I think there's little or no risk for trouble if you mix seroquel with adderall. But if SWIY thinks that it's a bad idea, then don't try it. Otherwise, SWIM thinks that it's a fun combo.

[Matt The Funk]

SWIM thinks you're wrong. SWIM thinks seroquel is drug that is really hard on the body. SWIM took 300mg a day and quit because of the load. Uppers and Downers in general do not mix. Seroquel greatly suppresses breathing. SWIM consumed other substances on Seroquel, and has done other combo's with it as well. But it seems like a pretty bad idea for SWIM, looks like someone is begging for a fucked up heart rate in my opinion.
SWIM thinks it sounds like a lame pseudo-speedball.
Also Swim knows someone who was at one point prescribed both Seroquel and Adderall XR , although they were taken at opposite times of day.

[OhCasey]

Originally Posted by vile_audio

seroquel basically stops all dopamine action amphetamines basically mimic dopamine


this is a bad idea

one time after a three wk long run with under 50 hrs of sleep vile took a 200mg seroquel

he stayed in bed for a week sleepin 23 hours outta the day

he could barely lift his spoon to eat cereal

fuck that i like having dopamine in my synapses at all times

I wouldnt blame the adderall and seroquel as much as the going 3 weeks on under 50 hours sleep. And as far as someone saying doctors wont prescribe it to be taken at the same time that makes sense since seroquels prescribed alot for sleep and adderall makes you not tired. But i wouldnt be surprised if theres people who take it for being bipolar and also have add and take adderall at the same time. Theres no bad interactions between the two. And alot of people take it concurrently with adderall XR and since adderall xr half life is around 10-13 hours most people on both meds are using seroquel with large amount of adderall still in there system.

[BearClaw]

To kbsuperstar, since swiy is prescribed seroquel, (if you have been taking it for a good period of time) swiy's body can adapt to its effects and be able to take other drugs, without the effect most get from seroquel.

But for all to note, Swims psychiatrist is currently prescribing him 40mg's of adderall IR for adhd, effexor (anti-depressant), and 25mg's seroquel for insomnia. On the other hand, swim didn't even bother filling the seroquel, due to its nasty effects, so, yeah..

[OhCasey]

Originally Posted by Matt The Funk

SWIM thinks you're wrong. SWIM thinks seroquel is drug that is really hard on the body. SWIM took 300mg a day and quit because of the load. Uppers and Downers in general do not mix. Seroquel greatly suppresses breathing. SWIM consumed other substances on Seroquel, and has done other combo's with it as well. But it seems like a pretty bad idea for SWIM, looks like someone is begging for a fucked up heart rate in my opinion.
SWIM thinks it sounds like a lame pseudo-speedball.
Also Swim knows someone who was at one point prescribed both Seroquel and Adderall XR , although they were taken at opposite times of day.

Swim thinks this post is uninformative. "Uppers and Downers dont Mix"? Its to easy to classify drugs as an upper or downer and say dont mix the two classes. Really Drugs are far more complicated and should be treated on a drug by drug basis. And Swim takes uppers and Downers together every week, Opiates and Adderall XR and he has esperienced NO bad side effects. Since you have taken Seroquel you could use your experiences to help rather then just say other people are wrong when you havent used the combo Adderall/Seroquel. Also if you read KBs post youd see SwiKB used it in small quanities where its commonly used with adderall to help sleep not in the large quanities Swiy used which is usually used to help people with bipolar disorder. Kbs post was a very informative report on the mixing of both Seroquel and included dosing. Then everyone offered up there uninformed opinions on the drugs based solely on the myths that if you combine an "upper & Downer" that your brain is going to over heat and you'll DIE. I like how when anyone brings up uppers and downers people mention Speedballs a speedball is bad cause its Herion and Cocaine or Morphine and Meth iv'd at the same time not because its an upper and downer. Just remember people will read what you write looking for info on a subject and if you were looking for info you wouldnt want people posting myths and popular misconceptions right next to someones actual experience and report of the use of a substance/s. Thanks for the informative thread KBsuperstar im sure people are finding it useful since it already has quite alot of views.
Someone should make a seroquel thread for everyone to air there opinions and lock KB's xperience report on Adderall & Seroquel. Come to think of it there is a seroquel experience thread in the antipsychotics forum.

[JudgeJudy]

Doc prescribed SWIM Seroquel and it caused nightmares. Then the next day couldn't wake up. Finally took Adderall and it lifted the fogginess but still felt like a zombie. If SWIY wants to sleep it's good for that, but otherwise it sucks.

[Matt The Funk]

Originally Posted by OhCasey

Swim thinks this post is uninformative. "Uppers and Downers dont Mix"? Its to easy to classify drugs as an upper or downer and say dont mix the two classes. Really Drugs are far more complicated and should be treated on a drug by drug basis. And Swim takes uppers and Downers together every week, Opiates and Adderall XR and he has esperienced NO bad side effects. Since you have taken Seroquel you could use your experiences to help rather then just say other people are wrong when you havent used the combo Adderall/Seroquel. Also if you read KBs post youd see SwiKB used it in small quanities where its commonly used with adderall to help sleep not in the large quanities Swiy used which is usually used to help people with bipolar disorder. Kbs post was a very informative report on the mixing of both Seroquel and included dosing. Then everyone offered up there uninformed opinions on the drugs based solely on the myths that if you combine an "upper & Downer" that your brain is going to over heat and you'll DIE. I like how when anyone brings up uppers and downers people mention Speedballs a speedball is bad cause its Herion and Cocaine or Morphine and Meth iv'd at the same time not because its an upper and downer. Just remember people will read what you write looking for info on a subject and if you were looking for info you wouldnt want people posting myths and popular misconceptions right next to someones actual experience and report of the use of a substance/s. Thanks for the informative thread KBsuperstar im sure people are finding it useful since it already has quite alot of views.

Listen buddy. I gave some experience input. I mean SWIM did. SWIM is experienced with popping pills, and was prescribed seorquel for a while and has taken doses into the 1,000mg range. SWIM has also taken plenty of uppers and downers together. In general health wise, uppers and downers don't mix. How do you find this uninformative?
To tell you the truth SWIM has smoked methamphetamines on lower doses of seroquel, and once he was prescribed it at higher doses. At lower doses there was no cool extra buzz. At higher doses it became a waste of money. In general this sounds like a really lame pseudo-speedball. Seroquel is an anti-psychotic and it shouldn't be taken lightly. SWIM also use to take uppers and downers everyrday...and is currently getting off medication on his own with the help of cannabis and the internet. Stupid, yes. Anyways it'd be good to read up some experience reports on both, then just understand what a mix of uppers and downers feels like. Seroquel can make you brain dead, and adderall can make your brain alive. Who knows. SWIM doesn't think this is a safe, smart, or most likely fun combo. But SWIY can feel free to try it if they must. SWIM thinks it is sad seeing people abuse Seroquel...ALSO IT HAS NOTHING TO DO WITH IT BEING COKE AND HEROIN. It's the fact that it's a stimulant and depressant.

[thenightwatch]

I haven't heard what Adderall + Seroquel feels like yet. Does it really feel that different from Seroquel alone? Or sobriety, even?

[OhCasey]

Originally Posted by Matt The Funk

Listen buddy. I gave some experience input. I mean SWIM did. SWIM is experienced with popping pills, and was prescribed seorquel for a while and has taken doses into the 1,000mg range. SWIM has also taken plenty of uppers and downers together. In general health wise, uppers and downers don't mix. How do you find this uninformative?
To tell you the truth SWIM has smoked methamphetamines on lower doses of seroquel, and once he was prescribed it at higher doses. At lower doses there was no cool extra buzz. At higher doses it became a waste of money. In general this sounds like a really lame pseudo-speedball. Seroquel is an anti-psychotic and it shouldn't be taken lightly. SWIM also use to take uppers and downers everyrday...and is currently getting off medication on his own with the help of cannabis and the internet. Stupid, yes. Anyways it'd be good to read up some experience reports on both, then just understand what a mix of uppers and downers feels like. Seroquel can make you brain dead, and adderall can make your brain alive. Who knows. SWIM doesn't think this is a safe, smart, or most likely fun combo. But SWIY can feel free to try it if they must. SWIM thinks it is sad seeing people abuse Seroquel...ALSO IT HAS NOTHING TO DO WITH IT BEING COKE AND HEROIN. It's the fact that it's a stimulant and depressant.

How do i find "In general health wise, uppers and downers don't mix" uninformative? Because its not true and its incredibly vague. In general health wise downers with downers dont mix. In general heath wise drugs in general arent that healthy. Its far more dangerous to mix Depressants like alcohol and barbituates then any upper & downer combo. "To tell you the truth SWIM has smoked methamphetamines on lower doses of seroquel, and once he was prescribed it at higher doses. At lower doses there was no cool extra buzz. At higher doses it became a waste of money." Theres Swiyour own peronal history of mixing seroquel with an amphetamine thats the only useful info Swiy has added to this thread and it really isnt too relative to what KB posted since he did a lil seroquel and and Adderall not Seroquel and Meth containing who knows what, cooked up in a garage or factory in mexico. Now that sounds like a lame pseudo Speedball. Im not saying it should be taken lightly but its really only used as an anti-psychotic in high doses, at low doses its prescribed to lil kids with add to help them sleep. I never understood how adderall or seroquel worked until i read "Seroquel can make you brain dead, and adderall can make your brain alive" so thank you for that. If you think a speedball being bad for you has nothing to do with it being that Coke is bad and Herion is bad for you then you really dont know anything about stimulants and depressants. Since you can combine many types of stimulants and depressants without any bad effects ie coffee and Oxycontin. You cant generalize by saying mixing stimulants and depressants is bad when mixing meth and cocaine is worse then adderall and seroquel. Or even 2 depressants like Xanax and alcohol is way worse then seroquel and Adderall could ever be. Mixing uppers and Downers is no different then mixing hallucinogens with uppers, downers or any combo of those three. You think its sad for people to abuse Seroquel? Well thats you cause I wouldnt pass judgemnet on other peoples choice of drugs especially if i had abused meth before but thats me. If Seroquel and Adderall were so dangerous why would docs all over the country prescribe to be used just hours apart. If it was so bad they wouldnt take a chance of giving it to lil kids just 5-6 hours after a dose of adderall.
Thenightwatch: "It brings SWIY from a state of fatigue and sleepiness to being really sped out and hyper, back and forth and back and forth. It's quite entertaining" -Kbsuperstar. Sounds like it feels similiar to that.

[thenightwatch]

Originally Posted by OhCasey

Thenightwatch: "It brings SWIY from a state of fatigue and sleepiness to being really sped out and hyper, back and forth and back and forth. It's quite entertaining" -Kbsuperstar. Sounds like it feels similiar to that.

Apologies, my mind has apparently left me, it's late. =)

That description confuses me. I'm unsure of why this combination would create that effect based on the pharmacology of the two drugs. I would be concerned about an irregular heartbeat in this occasion...

Next time SWIY (any of swiy) does this combination, could you keep track of your heart rate? For me, this is past the point of trying to convince of the ill-advised nature of this combination, and evolved purely into interest in the unique properties of this chemical chimera that I would never personally divulge in.

Its like a catecholamine tug-of-war. Kind of fascinating, really. =)

[kbsuperstar]

First off, thanks OhCasey for backing me up and contributing your information to this thread.

Secondly, I think the big misconception being perceived by those who think seroquel is significantly dangerous has to do with the fact that it's classified as an anti-psychotic. As I've stated before, seroquel has no chemical properties that combat psychosis in low doses. Doctors prescribe seroquel to people who take amphetamines for ADD/ADHD because it helps them sleep at night, and it can alleviate mania, aggression and irritability - which are side-effects experienced by many people who are on adderall and other ADD/ADHD medication.

Also, doctor's prescribe seroquel at low doses to people who experience anxiety and/or depression. This is usually done in conjunction with an anti-depressant (especially if someone has switched from one anti-depressant to another) because seroquel aids the body's absorption of a drug it's unfamiliar with - though, this characteristic is only seen when used with anti-depressants (which is a good thing!). Seroquel boosts the effectiveness of anti-depressants by allowing more dopamine, norepinephrine, and serotonin to be disinhibited in the brain.

On another quick note, when I last spent time in a psych ward, the main doctor (who worked with both children and adults throughout the hospital) always started off newly admitted patients on wellbutrin and seroquel. The wellbutrin is meant to increase dopamine and norepinephrine levels in the brain, and the seroquel is used simply to help the body become used to the drug more quickly.

Thanks to everyone who has contributed information to this thread. I hope you all find it useful!

[Matt The Funk]

I don't think you have any idea what the fuck you're talking about. Mixing uppers and downers strains your heart. Listen, SWIM has had major heart problems because of uppers and downers. The combo ruined his heart beat. So if you want to live in denial land go ahead. Feel free for SWIY to die from heart related problems. Yes also mixing downers is a bad idea, same with mixing stimulants.
Also see, the thing is THEY WOULD TAKE A CHANCE. THEY DON'T GIVE A FUCK. It's safe in a certain sense, but something I wouldn't recommend to anyone. At all. Your logic makes sense, you just don't understand what I'm saying about how straining it is. SWIM has been prescribed uppers in the morning, with downers at night. That is relatively safe. The whole idea of Seroquel has SWIM baffled though as to why someone would want this. Also SWIM's amphetamine's were picked up directly from a known cook in the area, who has since disappeared.

And yes the anti-psychotic properties may be at higher doses, SWIM just really dis-believes in seroquel and hates it, it bias's his opinion.

SWIM would appreciate it if O casey didn't reply to this (simply because he is very manic and may suddenly fly into rage at the rate he is going), but he respects his opinion.

It's sad to abuse Seroqeul because of what kind of drug it is. SWIM has abused it before. There is no real high. You get sedated and brain dead. Thats about it.

As I said earlier look up what psuedo-speedball reports are like and it would be something like that, with less euphoria and most likely more uncomfortable.

SWIM has plenty of experience with seroquel and adderall, mostly XR.
SWIM knows that seroquel is prescribed for anxiety and insomnia in low doses (has taken it after and before anti-psychotic doses for these reasons).

If SWIY does this combo, SWIM suggests just using an opiod or benzo instead. Or saving that seroquel for night to help ease the comdown.