Drug info - triazolo-benzodiazepines

[Politicalchalk]

last time swim was at his neurologist, among the medications we discussed was xanax, or, alprazolam if you prefer. Now, alprazolam, as well triazolam (Halcion), and Swim is sure there's others. Swim's read a bit about them, they were discovered later than "classic" benzos (diazepam et al.), and are considered to have rather different events or experiences with it.

Here's what Swim know: they have a shorter half-life, so I'm assuming they're aren't as long lasting as the classics. They are more addictive, relatively speaking, probably due to the short half-life. Finally, I believe they have anti-depressant properties (alprazolam).

One doesn't seem to come across them as much.

So swim asks: does anyone have CLINICAL information about the differences? Anyone with notable experiences? What about it's relation to diazepam or clonazepam...they're good "refrence points" for studies and theory, how might the triazolo's do comparatively ? Are they used for mainly anxiety and panic attacks, sleep, muscle relaxation, adjunct in some way to an anesthetic? With a short half-life, it seems like a good choice to add to the cocktail. Are there others? It seems like sedative/hypnotic research has died down and moved to the "nonbenzodiazepines/ "Z" drugs. Any specific information that's relevant but not listed?

Sorry this was so long, I hope it stimulates discussions!


PS -- FREE TIBET! A lot of terrible things are happening there right now, they deserve to be free of Communist China's rule! They deserve their liberty! their democracy! their right to self-determination!

[moda00]

Swim will check for more research, but for now she can answer one question and say that in her area, triazolam is most commonly utilized for partial/conscious sedation for minor dental procedures ("sleep dentistry"), minor surgeries, etc., although Medline states its more common/proper usage is for short term relief of sleep problems- insomnia, 7-10 days in a row max. Alprazolam seems to be most often prescribed for acute anxiety/panic attacks, and clonazepam seems to be also frequently utilized for anxiety, but often is taken for longer periods, daily, often even several times a day. Will this be used sporadically/as needed or daily/multiple daily doses? That could influence choice of half life, but there are such varied figures on that anyways..

Swim's experience has been that alprazolam come on a bit quicker/stronger and lasts a bit shorter as far as the duration (compared to clonazepam/diazepam), seems to mak her a bit "drunker" and less coherent than clonazepam or diazepam, that's not combined with alcohol or anything.. but for that to really be helpful it would take equivalent dosing and adequate reporting on efects, which swim unfortunately hasn't done, this is just her general/overall impression.. will try to find something more useful for ya, but hope that helps a little for now..